Each year thousands of patients face life-long losses in sensation and motor function from spinal cord injury and related conditions in which axons are badly damaged or severed. New research in mice shows, however, that gains in functional recovery from these injuries may be possible, thanks to a molecule known as Lin28, which regulates cell growth.
четверг, 30 апреля 2020 г.
Children who have difficult relationships with their moms are clingy towards teachers
Children who experience 'dependent' or clingy relationships with their preschool teachers tend to also have difficulties in their relationships with their mothers finds researchers. They went even further to find that later in elementary school, these children were prone to being anxious, withdrawn, and overly shy.
Better understanding of nature's nanomachines may help in design of future drugs
Many of the drugs and medicines that we rely on today are natural products taken from microbes like bacteria and fungi. Within these microbes, the drugs are made by tiny natural machines known as nonribosomal peptide synthetases (NRPSs). A research team has gained a better understanding of the structures of NRPSs and the processes by which they work. This improved understanding of NRPSs could potentially lead to the creation of new potent antibiotics, immunosuppressants and other modern drugs.
Ten Clinical Tips on COVID-19 for Healthcare Providers Involved in Patient Care
Ten Clinical Tips on COVID-19 for Healthcare Providers Involved in Patient Care
COVID-19 Contact Tracing Training Guidance and Resources
COVID-19 Contact Tracing Training Guidance and Resources
High cost of cancer drugs not always justified
Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices? An international study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clinical benefit of drugs to be better reflected in pricing.
Mind-controlled arm prostheses that 'feel' are now a part of everyday life
For the first time, people with arm amputations can experience sensations of touch in a mind-controlled arm prosthesis that they use in everyday life. A study reports on three Swedish patients who have lived, for several years, with this new technology -- one of the world's most integrated interfaces between human and machine.
Reduced obesity for weighted-vest wearers
Scientists have found a new method of reducing human body weight and fat mass using weighted vests. The new study indicates that there is something comparable to built-in bathroom scales that contributes to keeping our body weight and, by the same token, fat mass constant.
Double bubbles pierce with less trouble
Two microscopic bubbles penetrate soft materials better than one, concludes a new study by engineers. Optical cavitation uses a laser to form bubbles in a liquid that expand rapidly then collapse. The new article shows two bubbles produce long, fine jets that penetrate far enough with only five pulses to make cavitation potentially suitable for transfection or needle-free injections.
Protein mystery of three brain diseases unraveled
The accumulation of one particular protein in the brain is at the basis of three very different age-related conditions. Until recently, nobody understood how this was possible. Research now reveals that the shape of the protein determines the clinical picture.
среда, 29 апреля 2020 г.
COVID-19 Staffing Guidance for State, Tribal, Local, and Territorial Health Departments
This web page contains COVID-19 staffing guidance for state, tribal, local, and territorial health departments.
Computational techniques explore 'the dark side of amyloid aggregation in the brain'
As physicians and families know too well, though Alzheimer's disease has been intensely studied for decades, too much is still not known about molecular processes in the brain that cause it. Now researchers say new insights from analytic theory and molecular simulation techniques offer a better understanding of amyloid fibril growth and brain pathology.
Ultra-precision nano-sensor could detect iron disorders
Scientists have developed a hypersensitive nano-sensor to detect harmful 'free' iron disorders. The test could lead to earlier, more accurate disease diagnosis.
COVID-19 crisis: Millions of US workers at risk of infections on the job
New research shows that 14.4 million workers face exposure to infection once a week and 26.7 million at least once a month in the workplace, pointing to an important population needing protection as the novel coronavirus disease, COVID-19, continues to break out across the US.
Novel imaging application illuminates processes in cancer, COVID-19
Medical images for a wide range of diseases can be more easily viewed, compared, and analyzed using a breakthrough open source web-based imaging platform developed by Massachusetts General Hospital (MGH) and collaborating researchers.
Navigating the clean energy transition during the COVID-19 crisis
In a Commentary published April 29 in the journal Joule, energy and climate policy researchers in Switzerland and Germany provide a framework for responsibly and meaningfully integrating policies supporting the clean energy transition into the COVID-19 response in the weeks, months, and years to come.
Implant-free optogenetics minimizes brain damage during neuronal stimulation
A minimally invasive optogenetic technique that does not require brain implants successfully manipulated the activity of neurons in mice and monkeys, researchers report. The researchers first genetically engineered neurons to produce a newly developed, extremely light-sensitive protein called SOUL. They then demonstrated that it is possible to shine light through the skull to alter neuronal responses throughout the entire mouse brain, and to reach superficial regions of the macaque brain.
Bone proteomics could reveal how long a corpse has been underwater
When a dead body is found, one of the first things a forensic pathologist tries to do is estimate the time of death. There are several ways to do this, including measuring body temperature or observing insect activity, but these methods don't always work for corpses found in water. Now, researchers are reporting a mouse study showing that certain proteins in bones could be used for this determination.
Feeling burned out? The contributors could be more related to depression than you think
Researchers found that similar factors cause both medical intern burnout and depression. These findings can be used to identify and treat burnout as well as mitigate the risk of burnout by modifying workplace factors.
Model can predict hospital resilience for natural disasters, pandemics
Researchers have created a modeling tool that could help cities understand the full functionality and recovery of a healthcare system in the wake of a natural disaster. The model has wider implications for use in pandemics.
Molecular switch plays crucial role in learning from negative experiences
Neurobiologists have discovered how the signalling molecule Neuromedin U plays a crucial role in our learning process. The protein allows the brain to recall negative memories and, as such, learn from the past.
Arteries respond in opposite ways for males and females
A protein known to expand blood vessels -- key to controlling conditions like high blood pressure -- actually has different functions in males and females, new UC Davis Health research shows. Conducted using arterial cells from mice, the study is the first to identify sex-based distinctions in how the protein -- Kv2.1 -- works.
Schizophrenia related to abnormal fatty metabolism in the brain
Researchers have discovered a deficiency in the brains of people with schizophrenia that could lead to the development of new drug therapies. A postmortem comparison revealed that schizophrenia was associated with lower than normal levels of S1P, a type of fatty molecule found in the white matter of the brain.
Major trial shows breast cancer drug can hit prostate cancer Achilles heel
A drug already licensed for the treatment of breast and ovarian cancers is more effective than targeted hormone therapy at keeping cancer in check in some men with advanced prostate cancer, a major clinical trial reports. Olaparib, a pill lacking the side effects of chemotherapy, can target an Achilles heel in prostate cancers with a weakness in their ability to repair damaged DNA.
Study accurately tracks COVID-19 spread with big data
Researchers have developed a new method to accurately track the spread of COVID-19 using population flow data, and establishing a new risk assessment model to identify high-risk locales of COVID-19 at an early stage, which serves as a valuable toolkit to public health experts and policy makers in implementing infectious disease control during new outbreaks.
Sensitive new test detects antibodies against SARS-CoV-2 in only 10 minutes
A proof-of-concept study describes a quick, sensitive test for antibodies against the coronavirus in human blood. The test could help doctors track a person's exposure to the disease, as well as confirm suspected COVID-19 cases that tested negative by other methods.
Stark disparities in COVID-19 hospitalization and death rates among New York
Researchers found that COVID-19 hospitalization and death rates varied across New York City boroughs. The Bronx -- with the highest proportion of racial/ethnic minorities, the most poverty, and lowest educational attainment -- had higher rates of hospitalization and death related to COVID-19 than all other boroughs. These rates were lowest in affluent Manhattan, comprised of a predominately white population. COVID-19 deaths per 100,000 persons was nearly two times greater in the Bronx than in Manhattan.
Offspring may inherit legacy of their father's Toxoplasma infection
Researchers have revealed for the first time that males infected with the Toxoplasma parasite can impact their offspring's brain health and behavior. Studying mice infected with the common parasite Toxoplasma, the team discovered that sperm of infected fathers carried an altered 'epigenetic' signature which impacted the brains of resulting offspring. Molecules in the sperm called 'small RNA' appeared to influence the offspring's brain development and behavior.
Link identified between dietary selenium and outcome of COVID-19 disease
Researchers have identified a link between the COVID-19 cure rate and regional selenium status in China.
Children and Coronavirus Disease 2019 (COVID-19): Tips to keep children healthy while school's out
Children and Coronavirus Disease 2019 (COVID-19): Tips to keep children healthy while school's out
NIH clinical trial shows remdesivir accelerates recovery from advanced COVID-19
Hospitalized patients with advanced COVID-19 and lung involvement who received remdesivir recovered faster than similar patients who received placebo, according to a preliminary data analysis from a randomized, controlled trial involving 1063 patients.
First randomized trial of remdesivir suggests antiviral drug is not associated with significant clinical benefits, more research needed
Treatment with the antiviral drug remdesivir does not speed recovery from COVID-19 compared with placebo in hospitalized patients who are critically ill, according to the first randomized trial of its kind involving 237 adults from 10 hospitals in Wuhan, China.
Researchers help give robotic arms a steady hand for surgeries
Steady hands and uninterrupted, sharp vision are critical when performing surgery on delicate structures like the brain or hair-thin blood vessels. While surgical cameras have improved what surgeons see during operative procedures, the 'steady hand' remains to be enhanced -- new surgical technologies, including sophisticated surgeon-guided robotic hands, cannot prevent accidental injuries when operating close to fragile tissue.
To prevent antimicrobial resistance, vaccinate the world's kids
Childhood vaccination may be a powerful tool in the fight against antimicrobial resistance in low- and middle-income countries, finds a new analysis. The study found that immunization with two common vaccines -- the pneumococcal conjugate and rotavirus vaccines -- significantly reduces the rates of acute respiratory infections and diarrhea among small children in these settings. And, with fewer children getting sick or severely sick, fewer are receiving antibiotic treatment.
Simple 'sniff test' reliably predicts recovery of severely brain injured patients
The ability to detect smells predicts recovery and long-term survival in patients who have suffered severe brain injury, a new study has found. A simple, inexpensive 'sniff test' could help doctors to accurately diagnose and determine treatment plans for patients with disorders of consciousness.
Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens from Persons for Coronavirus Disease 2019 (COVID-19)
Health care providers should contact their local/state health department immediately to notify them of patients with fever and lower respiratory illness who they suspect may have COVID-19.
Contact Tracing : Part of a Multipronged Approach to Fight the COVID-19 Pandemic
Contact Tracing : Part of a Multipronged Approach to Fight the COVID-19 Pandemic
Reopening Guidance for Cleaning and Disinfecting Public Spaces, Workplaces, Businesses, Schools, and Homes
Reopening Guidance for Cleaning and Disinfecting Public Spaces, Workplaces, Businesses, Schools, and Homes
Higher thrombus risk in men with obesity in adolescence
Men with a history of obesity in their late teens are, in adult life are more at risk of a blood clot (thrombus) in a leg or lung, according to a new study. The risk rises successively and is highest in those who were severely obese in adolescence.
вторник, 28 апреля 2020 г.
Scientists recreate DNA damage caused by toxins from smoking
Researchers have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking. The causes of bladder cancer remain largely unknown, however smoking is seen as the main risk factor for the disease.
Open access hardware and 3D printing can help tackle demand for health supplies
Free open source hardware and 3D printing could help to alleviate the burden of Covid-19 on global health systems, according to scientists.
Urban slums are uniquely vulnerable to COVID-19: Here's how to help
Government-enforced social isolation can be devastating for the nearly 1 billion people around the globe currently dwelling in urban slums, where physical space is scarce and many rely on daily wage labor for survival. A new report, authored by a team of public health experts and epidemiologists working in collaboration with community leaders and non-governmental organizations, provides eight urgent recommendations for reducing the impact of COVID-19 on people living in poverty.
Making sense of the viral multiverse
Researchers propose a new classification system, capable of situating coronaviruses like SARS-CoV-2 within the enormous web of viruses across the planet, known as the virosphere.
Experts successfully treat severe case of COVID-19 in 3-week-old infant
In one of the first reported cases of its kind, a 3-week-old infant in critical condition recovered from COVID-19 due to rapid recognition and treatment by physicians from McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).
Work-related stress linked to increased risk for peripheral artery disease
People who reported work-related stress were more likely to be hospitalized for treatment of peripheral artery disease compared to those who did not report work-related stress. Work-related stress, or job strain, refers to psychological and social stress at work, often from high expectations combined with lower levels of personal control.
New type of immune cell discovered in breast ducts
Breast cancer researchers have discovered a new type of immune cell that helps to keep breast tissue healthy by regulating a vital process within mammary ducts - the sites where milk is produced and transported, but also where most breast cancers arise.
A child's home environment can impact the risk of developing depression
New research finds that children's rearing environment has a meaningful impact on their risk for major depression later in life, and notes the importance supporting of nurturing environments when children are at risk.
Gut microbes influence how rat brains react to opioids
Antibiotic treatment -- which depletes gut microbes -- drastically changes the parts of a rat's brain that are activated during opioid addiction and withdrawal.
Spinal cord gives bio-bots walking rhythm
Miniature biological robots are making greater strides than ever, thanks to the spinal cord directing their steps. Researchers developed the tiny walking 'spinobots,' powered by rat muscle and spinal cord tissue on a soft, 3D-printed hydrogel skeleton. While previous generations of biological robots, or bio-bots, could move forward by simple muscle contraction, the integration of the spinal cord gives them a more natural walking rhythm.
How mistakes help us recognize things
When we look at the same object in quick succession, our second glance always reflects a slightly falsified image of the object. Guided by various object characteristics such as motion direction, color and spatial position, our short-term memory makes systematic mistakes. Apparently, these mistakes help us to stabilize the continually changing impressions of our environment.
How the heart affects our perception
When we encounter a dangerous situation, signals from the brain make sure that the heart beats faster. When we relax the heart slows down. But the heartbeat also affects the brain but the underlying mechanisms are unclear. Researchers have now identified two mechanisms underpinning how the heart influences our perception, the brain, and how these mechanisms differ between individuals.
Researchers' method holds promise for brain study, better tests for viruses
Researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases.
Light-based deep brain stimulation relieves symptoms of Parkinson's disease
Biomedical engineers have used light-based deep brain stimulation to treat motor dysfunction in an animal model of Parkinson's disease. Succeeding where earlier attempts have failed, the method promises to provide new insights into why deep brain stimulation works and ways in which it can be improved on a patient-by-patient basis.
Early high school start times adversely affect attendance
A new study finds that earlier high school start times can have significant adverse consequences for students, including increased rates of tardiness and absenteeism.
Key Strategies to Prepare for COVID-19 in Long-term Care Facilities (LTCFs)
Key Strategies to Prepare for COVID-19 in Long-term Care Facilities (LTCFs)
Immune-regulating drug improves gum disease in mice
A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study.
Smart contact lenses that diagnose and treat diabetes
Medical researchers have develops wireless smart contact lenses for diagnosis and treatment of diabetes.
Hugs and kisses: Research connects affection, attachment style and marriage satisfaction
Go ahead: Give your partner a hug or cuddle while you catch some Netflix. According to recently published research, it just might build a stronger relationship.
People with brown fat may burn 15% more calories
Short-term cold exposure may help people with brown fat burn 15% more calories than those without, according to a small study.
Visual-spatial learning disorder is more common than thought, finds study
Researchers estimate non-verbal learning disorder may affect up to 3 million children in the United States.
Red-flagging misinformation could slow the spread of fake news on social media
A new study on the spread of disinformation reveals that pairing headlines with credibility alerts from fact checkers, the public, news media and even AI, can reduce peoples' intention to share. However, the effectiveness of these alerts varies with political orientation and gender.
понедельник, 27 апреля 2020 г.
Testing for COVID-19
If you are a close contact of someone with COVID-19 or you are a resident in a community where there is ongoing spread of COVID-19 and develop symptoms of COVID-19, call your healthcare provider and tell them about your symptoms and your exposure.
Evaluating and Reporting Persons Under Investigation (PUI)
Evaluating and Reporting Persons Under Investigation (PUI)
COVID-19 Guidance for Shared or Congregate Housing
COVID-19 Guidance for Shared or Congregate Housing
Global case numbers are reported by the World Health Organization (WHO)
Global case numbers are reported by the World Health Organization (WHO) in their coronavirus disease 2019 (COVID-19) situation report. For U.S. information, visit CDC's COVID-19 in the U.S.
Coupled magnetic materials show interesting properties for quantum applications
Researchers have uncovered a novel way in which the excitations of magnetic spins in two different thin films can be strongly coupled to each other through their common interface.
Eye pupil an indicator of effective decision making
Researchers are investigating how eye-pupil size changes can indicate a person's cognitive state as a means to enable teaming with autonomous agents.
New understanding of asthma medicines could improve future treatment
New research has revealed new insights into common asthma aerosol treatments to aid the drug's future improvements which could benefit hundreds of millions of global sufferers.
Interim Guidance for Implementing Home Care of People Not Requiring Hospitalization for Coronavirus Disease 2019 (COVID-19)
Guidance for staff at local and state health departments, infection prevention and control professionals, and healthcare personnel who are coordinating the home care and isolation1 of people with confirmed or suspected COVID-19 infection, including persons under investigation.
Antibiotic exposure can 'prime' single-resistant bacteria to become multidrug-resistant
Researchers report that, for a bacterial pathogen already resistant to an antibiotic, prolonged exposure to that antibiotic not only boosted its ability to retain its resistance gene, but also made the pathogen more readily pick up and maintain resistance to a second antibiotic and become a dangerous, multidrug-resistant strain.
New tool measures quality of life in people with dementia
University of Queensland researchers say a new tool to measure of the quality of life of people with dementia will result in better targeted care for those living with the condition.
Smart interventions reduce malaria transmission by 75%
Mass drug administration and vector control can help eliminate malaria. A vector refers to an organism that transmits infection, as mosquitoes infected with parasites transmit malaria to people.
Scientists unveil how general anesthesia works
The discovery of general anesthetics -- compounds which induce unconsciousness, prevent control of movement and block pain -- helped transform dangerous operations into safe surgery. But scientists still don't understand exactly how general anesthetics work. Now, researchers have revealed how a general anesthetic called isoflurane weakens the transmission of electrical signals between neurons, at junctions called synapses.
Disappearance of animal species takes mental, cultural and material toll on humans
The research reveals that hunter-gatherer societies expressed a deep emotional and psychological connection with the animal species they hunted, especially after their disappearance. The study will help anthropologists and others understand the profound environmental changes taking place in our own lifetimes.
Herpes virus decoded
The genome of the herpes simplex virus 1 was decoded using new methods. Hundreds of previously unknown gene products were found. The virus causes lip herpes, but can also be life-threatening.
воскресенье, 26 апреля 2020 г.
Traffic officer protein governs speed of sugar/fat conversion pathway
Scientists have identified a protein sensor that restricts how much sugar and fat our cells convert into energy during periods of starvation. It is possible, the scientists say, that the sensor could be fine-tuned to prompt more sugar and fat conversion in people with metabolic conditions.
Structure of biocatalysts depends on whether they are in cells or test tubes
The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable 'hinges.' The shape of enzymes can depend on whether their structure is measured in the test tube or in the living cell. This is what physicochemists discovered about YopO, an enzyme of the plague pathogen.
Holistic approach best for tackling nonmedical drug use, study finds
Health practitioners are constantly developing new ways to help those with drug and alcohol addictions wean themselves from their substance of choice. Most such programs have limited success, however. A new study finds that interventions that take a multidimensional approach -- tackling the biological, social, environmental and mental health obstacles to overcome while also addressing a person's substance use -- work best for those hoping to stop using drugs.
Syphilis eludes immune attack by altering a single gene
Shuffling of DNA in a single gene might be why the syphilis bacteria can evade the immune system. The change alters a protein on its cell surface to create a distraction. People can become re-infected several times with syphilis because they can't develop immunity, Untreated syphilis can hide in the body for decades. Genomic findings on these evasive strategies may point to designs for vaccines to outwit syphilis' defenses.
Meat and Poultry Processing Workers and Employers
Guidance for Meat and Poultry Processing Workers and Employers
Boosting the immune system's appetite for cancer
A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission.
Breakthrough discovery in HIV research opens path to new, better therapies
Cells infected with HIV make two forms of the virus's RNA. A new article finds a single nucleotide controls which version of viral RNA an infected cell makes; both forms are necessary for HIV to replicate. The critical nucleotide happens to be in a region of the HIV genome with low mutation rates. That placement makes it a promising target for new therapies, because the virus is less likely to develop resistance.
3D face photos could be a sleep apnea screening tool
Facial features analyzed from 3D photographs could predict the likelihood of having obstructive sleep apnea, according to a new study.
A new therapeutic target turns the immune system against lymphoma
Scientists have identified a key mechanism that tumor cells use to take advantage of and avoid detection from the immune system. Targeting this mechanism offers a new therapeutic strategy for cancers like Non-Hodgkin lymphoma.
Good news for the wheat-sensitive among us
New research has revealed key insights about the proteins causing two of the most common types of wheat sensitivity - non-celiac wheat sensitivity and occupational asthma (baker's asthma).
How hearing loss in old age affects the brain
If your hearing deteriorates in old age, the risk of dementia and cognitive decline increases. So far, it hasn't been clear why. A team of neuroscientists has examined what happens in the brain when hearing gradually deteriorates: key areas of the brain are reorganized, and this affects memory.
Falling visibility shows African cities suffering major air pollution increases
Falling visibility in three major African cities reveals that air pollution has increased significantly over the last 45 years - leaving citizens facing further short-term increases in human-made pollution due to increasing urbanization and economic development, a new study reveals.
Eye contact activates the autonomic nervous system even during video calls
A new study found that eye contact during video calls can elicit similar psychophysiological responses than those in genuine, in-person eye contact.
суббота, 25 апреля 2020 г.
Information for Clinicians on Therapeutic Options for COVID-19 Patients
Information for Clinicians on Therapeutic Options for COVID-19 Patients
Dietary counselling introduced in infancy leads to better cardiovascular health in adults
Scientists investigated the long-term effects of dietary counseling on cardiovascular health. The individuals, who had participated in the trial between ages 7 months and 20 years, were invited to a follow-up study at the age of 26. The results show that the intervention group who received dietary counseling had lower serum cholesterol level and better insulin sensitivity than those in the control group.
пятница, 24 апреля 2020 г.
U.S. State and Local Public Health Laboratories Reporting to CDC
U.S. State and Local Public Health Laboratories Reporting to CDC
Percentage of Visits for ILI by Age Group Reported by A Subset of ILINet Providers
Percentage of Visits for ILI by Age Group Reported by A Subset of ILINet Providers
Emergency Department Visits Percentage of Visits for COVID-19-Like Illness (CLI) or Influenza-like Illness (ILI)
Emergency Department Visits Percentage of Visits for COVID-19-Like Illness (CLI) or Influenza-like Illness (ILI)
U.S. Clinical Laboratories Reporting SARS-CoV-2 Test Results to CDC
U.S. Clinical Laboratories Reporting SARS-CoV-2 Test Results to CDC
U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet): Overall Percentage of Visits for ILI
U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet): Overall Percentage of Visits for ILI
After a heart attack, physical activity makes you feel better
Heart attack patients who take part in a lifestyle improvement program feel better -- especially when they do additional physical activity.
A cellular mechanism protecting against cancer
Researchers have discovered a natural protective mechanism that leads to the programmed death of potentially diseased cells. It protects from cancer that can develop as a result of irregular distribution of genetic information to daughter cells. The enzyme separase plays a central role in these processes.
New research highlights blood clot dangers of COVID-19
A special report published today in the journal Radiology outlines prevention, diagnosis and treatment of complications stemming from blood clots in patients with COVID-19. The journal also published two research letters and a case study on this topic.
The most promising strategies for defeating coronavirus: A review study
Experts from UNC Chapel Hill review possible clinical approaches from antivirals to gene therapy against the virus responsible for COVID-19 and related diseases.
The best material for homemade face masks may be a combination of two fabrics
Researchers report that a combination of cotton with natural silk or chiffon can effectively filter out aerosol particles -- if the fit is good.
Simple 'do it yourself' circuit to ventilate two patients at once is technically feasible
A simple 'do it yourself' breathing circuit, using accessories that are readily available in intensive care, can be used to ventilate two critically ill patients at once, should clinicians be faced with equipment shortages, new research suggests.
CDC in Action
CDC is aggressively responding to the global outbreak of COVID-19 and preparing for the potential of community spread in the United States.
Two steps closer to flexible, powerful, fast bioelectronic devices
Researchers have designed biocompatible ion-driven soft transistors that can perform real-time neurologically relevant computation and a mixed-conducting particulate composite that allows creation of electronic components out of a single material. These have promise for bioelectronic devices that are fast, sensitive, biocompatible, soft, and flexible, with long-term stability in physiological environments such as the human body. In particular, they could facilitate diagnosis and monitoring of neurological disease.
Nursing homes prepared for pandemics, but COVID-19 reveals gaps
New data suggests that Michigan nursing homes that responded to a survey were far better prepared for the COVID-19 pandemic than they were for the last one. The study includes responses from 130 nursing homes to a survey during the week that the state announced its first documented case of COVID-19.
COVID-19: The downside of social distancing
When faced with danger, humans draw closer together. Social distancing thwarts this impulse. Researchers argue that this dilemma poses a greater threat to society than overtly antisocial behavior.
'Bursty' email communication helps groups convert resources into results
A new study looked at more than 1,300 retail banking sales teams in a large regional bank to explore whether groups vary in how they convert resources into performance. The study found that resources are generally helpful, but groups differ in the results they achieve. The variation is also largely associated with the group's coordinated attention - specifically, their patterns of email communication. The findings have implications for how firms can operate more efficiently.
Coronavirus Disease 2019 Information for Travel (New Travel Alerts)
This page includes information about Coronavirus Disease 2019 (COVID-19) for travelers and travel-related industries.
Resources for State, Local, Territorial and Tribal Health Departments
Resources for State, Local, Territorial and Tribal Health Departments
Electronic skin fully powered by sweat can monitor health
Electronic skin monitors body's vitals signs while being powered by sweat.
New systematic review captures what makes a positive post-birth experience for new mothers
A new qualitative systematic review conducted to inform the scope of a new World Health Organization (WHO) post-birth (postnatal) guideline identifies four clear themes for a positive experience in mothers across 15 different countries and cultures.
Human uterus colonized by clones with cancer-driving mutations that arise early in life
Many cells in the inner lining of the uterus carry 'cancer-driving' mutations that frequently arise early in life, report scientists. The research team conducted whole-genome sequencing of healthy human endometrium, providing a comprehensive overview of the rates and patterns of DNA changes in this tissue.
четверг, 23 апреля 2020 г.
Guidance for U.S. Healthcare Facilities about Coronavirus (COVID-19)
Guidance for U.S. Healthcare Facilities about Coronavirus (COVID-19)
Clinical Care Guidance for Healthcare Professionals about Coronavirus (COVID-19)
Clinical Care Guidance for Healthcare Professionals about Coronavirus (COVID-19)
Interim Guidance for Reopening Employers with Vulnerable Workers
Interim Guidance for Reopening Employers with Vulnerable Workers
Assessing Risk Factors for Severe COVID-19 Illness
Assessing Risk Factors for Severe COVID-19 Illness
COVID-19 in Racial and Ethnic Minority Groups
The effects of COVID-19 on the health of racial and ethnic minority groups is still emerging; however, current data suggest a disproportionate burden of illness and death among racial and ethnic minority groups. Studies are underway to understand and potentially reduce the impact of COVID-19 on the health of racial and ethnic minorities.
Key nose cells identified as likely COVID-19 virus entry points
Two specific nose cell types have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells, which could help explain the high rate of transmission. The study with Human Cell Atlas Lung Biological Network found cells in the eye and some other organs also contain the viral-entry proteins.
Children who hold 'benevolent' sexist views are also likely to possess 'hostile' ones
Children who hold seemingly positive, 'benevolent' views about women are also likely to hold negative ones, a team of psychology researchers has found. Their results also show differences between boys and girls in how these views change over time.
How to make the healthiest coffee
What's the healthiest way to make a fresh cup of coffee? A new study examining links between coffee brewing methods and risks of heart attacks and death has concluded that filtered brew is safest.
Promising MERS coronavirus vaccine trial in humans
Scientists have now conducted a first-in-human trial with a vaccine against MERS (Middle East Respiratory Syndrome). The MVA-MERS-S vaccine was tolerated well and triggered the development of antibodies and T cell immunity.
DNA may not be life's instruction book -- just a jumbled list of ingredients
The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But one research suggests this might not be so. In two new papers, he argues DNA is just the ingredient list, not the set of instructions used to build and maintain a living organism. The instructions, he says, are stored in the molecules that regulate a cell's DNA and other functioning systems.
'Designer virus' is first new oral polio vaccine in 50 years
Virologists report promising Phase 1 clinical results for the first new oral polio vaccine in 50 years, which they have designed to be incapable of evolving the ability to cause disease in humans.
Researchers restore injured man's sense of touch using brain-computer interface technology
Researchers have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system. The technology harnesses neural signals that are so minuscule they can't be perceived and enhances them via artificial sensory feedback sent back to the participant, resulting in greatly enriched motor function.
Very low-dose Avastin effective for preventing blindness in preterm infants
Babies born prematurely who require treatment to prevent blindness from retinopathy of prematurity (ROP) could be treated with a dose of Avastin (bevacizumab) that is a fraction of the dose commonly used for ROP currently.
New test for COVID-19 may deliver faster results to more people
Scientists have developed a novel assay capable of detecting the causative viral pathogen of COVID-19 that can be run in decentralized test facilities, according to a new report.
Coronaviruses and bats have been evolving together for millions of years
Scientists compared the different kinds of coronaviruses living in 36 bat species from the western Indian Ocean and nearby areas of Africa. They found that different groups of bats have their own unique strains of coronavirus, revealing that bats and coronaviruses have been evolving together for millions of years. Developing a better understanding of how coronaviruses evolved can help us create better public health programs for the future.
Specialized nerve cells increase the appetite for high-fat foods
Fat activates nociceptin neurons in the hypothalamus of mice.
Decontamination and Reuse of Filtering Facepiece Respirators using Contingency and Crisis Capacity Strategies
Decontamination and Reuse of Filtering Facepiece Respirators using Contingency and Crisis Capacity Strategies
Spinal cord injury increases risk for mental health disorders
A new study finds adults with traumatic spinal cord injury are at an increased risk of developing mental health disorders and secondary chronic diseases compared to adults without the condition.
Effects of rapid-acting antidepressants consolidated in sleep?
Ketamine alleviates depressive symptoms within hours, with the most significant change typically seen a day after its administration. However, the symptoms often reappear within a week. According to researchers, neural connections strengthened by the quick treatment of depression are consolidated in the brain during the deep sleep periods of the following night. To prevent the circle of negative thoughts regaining supremacy, depressed patients also need therapy.
New heart attack testing protocol expedites treatment in ER
A new protocol using highly sensitive blood tests to determine whether someone is having a heart attack.
Which foods do you eat together? How you combine them may raise dementia risk
It's no secret that a healthy diet may benefit the brain. However, it may not only be what foods you eat, but what foods you eat together that may be associated with your risk of dementia, according to a new study.
From Voldemort to Vader, fictional villains may draw us to darker versions of ourselves
People may find fictional villains surprisingly likeable when they share similarities with the viewer or reader.
среда, 22 апреля 2020 г.
Communication Toolkit for Transportation Partners to Inform Road Travelers
Communication Toolkit for Transportation Partners to Inform Road Travelers
Contact Tracing : Part of a Multipronged Approach to Fight the COVID-19 Pandemic
Contact Tracing : Part of a Multipronged Approach to Fight the COVID-19 Pandemic
Frequently Asked Questions and Answers: Coronavirus Disease-2019 (COVID-19) and Children
Most confirmed cases of COVID-19 reported from China have occurred in adults.
Organic memory devices show promise for flexible, wearable, personalized computing
The advent of artificial intelligence, machine learning and the internet of things is expected to change modern electronics. The pressing question for many researchers is how to handle this technological revolution. Brain-inspired electronics with organic memristors could offer a functionally promising and cost- effective platform. Since memristors are functionally analogous to the operation of neurons, the computing units in the brain, they are optimal candidates for brain-inspired computing platforms.
Ultrasound-assisted molecule delivery looks to preserve blood for years
Blood can typically be stored for only six weeks after donation, but a potential solution attempts to dry blood by using a sugar-based preservative. New work in ultrasound technology looks to provide a path to inserting these sugars into human red blood cells, allowing the molecule trehalose to enter the cells and prevent their degradation when dried for preservation.
What helps couples weather financial storms
In financially challenging times, it's especially important to show your partner love and support, says researchers, who studied what contributes to couples' success in financially stressful times.
Cost-effective canopy protects health workers from COVID infection during ventilation
Researchers have designed a cost-effective, plastic canopy system that can help to protect healthcare workers who are at risk of airborne coronavirus infection while delivering noninvasive ventilation or oxygen via high flow nasal canula (HFNC). Noninvasive ventilation or HFNC is often used to support breathing following respiratory failure, which is a common symptom of severe coronavirus disease.
Low-cost, easy-to-build ventilator performs similarly to high-quality commercial device
A low-cost, easy-to-build non-invasive ventilator aimed at supporting the breathing of patients with respiratory failure performs similarly to conventional commercial devices. Researchers say the prototype ventilator could support treatment of coronavirus and other severe respiratory diseases in low income regions or where ventilator supplies are limited. The research paper provides a free to replicate, open source description for how to build the ventilator.
New application of machine learning and image analysis to help distinguish a rare subtype of kidney cancer
Despite significant obstacles presented by COVID-19, Regenstrief Institute Affiliated Scientist Jie Zhang, PhD, Regenstrief Institute Research Scientist Kun Huang, PhD, both Indiana University School of Medicine faculty members, and Jun Cheng, PhD of Shenzhen University conducted a study applying machine learning and image analysis to distinguish a rare subtype of kidney cancer (tRCC) while Dr. Cheng was quarantined in Wuhan.
Interim Operational Considerations for Public Health Management of Healthcare Workers Exposed to or Infected with COVID-19: non-US Healthcare Settings
Interim Operational Considerations for Public Health Management of Healthcare Workers Exposed to or Infected with COVID-19: non-US Healthcare Settings
A new biosensor for the COVID-19 virus
Researchers have developed a novel sensor for detecting the new coronavirus. In future, it could be used to measure the concentration of the virus in the environment -- for example, in places where there are many people or in hospital ventilation systems.
Scientists explore using 'own' immune cells to target infectious diseases including COVID-19
The engineering of specific virus-targeting receptors onto a patient's own immune cells is now being explored by scientists as a potential therapy for controlling infectious diseases, including the COVID-19-causing virus, SARS-CoV-2.
Segregation and local funding gaps drive disparities in drinking water
The fragmentation of water service in the US among thousands of community systems, most of which are small and rely on local funding, leaves many households vulnerable to water contamination or loss of service as droughts become more frequent, a new analysis finds. Households in low-income or predominantly minority neighborhoods face the highest risks. Making sure their taps don't run dry will require a fundamental re-evaluation of how water systems are managed and funded.
Virtual reality makes empathy easier
Virtual reality activates brain networks that increase your ability to identify with other people, according to new research published in eNeuro. The technology could become a tool in the treatment of violent offenders to empathize more with others.
Almost half of all postpartum psychosis are isolated cases
A new research result shows that 40% of the women who suffer a psychosis after giving birth -- known as postpartum psychosis - do not subsequently become ill again.
Link between obesity and sleep loss
Can staying up late make you fat? Researchers found the opposite to be true when they studied sleep in worms: It's not the sleep loss that leads to obesity, but rather that excess weight can cause poor sleep.
Researchers develop new microneedle array combination vaccine delivery system
In parallel to their current work on a potential coronavirus vaccine, researchers have developed a new vaccine delivery system for vaccines using live or attenuated viral vectors: a finger-tip sized patch that contains 400 tiny needles, each just half of one millimeter.
Novel class of specific RNAs may explain increased depression susceptibility in females
Researchers have found that a novel class of genes known as long non-coding RNAs (lncRNAs) expressed in the brain may play a pivotal role in regulating mood and driving sex-specific susceptibility versus resilience to depression.
Interim guidance for homeless service providers to plan and respond to coronavirus disease 2019 (COVID-19)
Interim guidance for homeless service providers to plan and respond to coronavirus disease 2019 (COVID-19)
вторник, 21 апреля 2020 г.
Considerations for Optimizing the Supply of Powered Air-Purifying Respirators (PAPRs)
Considerations for Optimizing the Supply of Powered Air-Purifying Respirators (PAPRs)
Operational Considerations for Personal Protective Equipment in the Context of Global Supply Shortages for Coronavirus Disease 2019 (COVID-19) Pandemic: non-US Healthcare Settings
Operational Considerations for Personal Protective Equipment in the Context of Global Supply Shortages for Coronavirus Disease 2019 (COVID-19) Pandemic: non-US Healthcare Settings
Human pregnancy is weird -- new research adds to the mystery
Scientists set out to investigate the evolution of a gene that helps women stay pregnant: the progesterone receptor gene. The results come from an analysis of the DNA of 115 mammalian species.
Pulse oximetry monitoring overused in infants with bronchiolitis
Monitoring blood oxygen levels with continuous pulse oximetry is being overused in infants with bronchiolitis who do not require supplemental oxygen, according to a new study. The researchers found the use of continuous pulse oximetry occurred frequently and varied widely among hospitals in their sample, despite national recommendations advising against the practice.
How the brain recognizes change
A research team revealed in an animal study a previously unknown role of a presynaptic adhesion molecule to tell the new change by regulating postsynaptic NMDA-type receptor responses at excitatory synapses.
CRISPR helps identify potential Alzheimer's-related protein
Experts have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the 'molecular scissors' of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease. Researchers tested a total of 19,150 individual genes for their effect on amyloid beta levels and ruled out all but one: calcium and integrin-binding protein 1 (CIB1).
Scientists identify cause of leakiness in eye diseases
Scientists have identified a key step in the process that leads to leaky vessels and harmful swelling in eye diseases.
Milestone for the early detection of sepsis
Researchers are developing a ground-breaking method that uses biomarkers to detect sepsis 2 to 3 days before the first clinical symptoms appear. This can significantly increase the chances of survival in cases of blood poisoning by bacteria or fungi.
Screening clients for respiratory infection symptoms at entry to homeless shelters
Screening clients for respiratory infection symptoms at entry to homeless shelters
Got seasonal allergies? Beetles could help
Allergies caused by the common ragweed, Ambrosia artemisiifolia, impact millions, and in Europe alone, around 13.5 million people suffer with symptoms, resulting in 7.4 billion Euros worth of health costs per year, according to the research. The study suggests the leaf beetle, Ophraella communa, could reduce the number of people affected by the pollen and the associated economic impacts, since the beetle -- itself a recent arrival in Europe -- loves to munch on the invasive plant.
Glaucoma could be successfully treated with gene therapy
A new study has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients.
Heavy cost of excessive drinking on people's decision making
A new study highlights how hangover inhibits individuals' 'core executive functions' with knock-on impacts for those currently working from home.
Antibodies could provide new treatment for OCD
Mental health conditions such as obsessive compulsive disorder could be treated in a new way using drugs that target the immune system, research suggests.
AI to make dentists' work easier
Researchers have developed a new automatized way to localize mandibular canals.
Information for Laboratories
This page includes interim guidance and resources for laboratory professionals working with specimens from persons under investigation (PUI) for coronavirus disease 2019 (COVID-19).
Continued CO2 emissions will impair cognition
New research finds that an anticipated rise in carbon dioxide concentrations in our indoor living and working spaces by the year 2100 could lead to impaired human cognition.
Age matters: Paternal age and the risk of neurodevelopmental disorders in children
It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.
понедельник, 20 апреля 2020 г.
What Mail and Parcel Delivery Drivers Need to Know about COVID-19
What Mail and Parcel Delivery Drivers Need to Know about COVID-19
Infant temperament predicts personality more than 20 years later
Researchers investigating how temperament shapes adult life-course outcomes have found that behavioral inhibition in infancy predicts a reserved, introverted personality at age 26. For those individuals who show sensitivity to making errors in adolescence, the findings indicated a higher risk for internalizing disorders (such as anxiety and depression) in adulthood. The study provides robust evidence of the impact of infant temperament on adult outcomes.
Origins of human language pathway in the brain at least 25 million years old
The human language pathway in the brain has been identified by scientists as being at least 25 million years old -- 20 million years older than previously thought.
Finding leukemia's weakness using genome-wide CRISPR technology
Researchers have used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia.
Stabilizing brain-computer interfaces
New research will drastically improve brain-computer interfaces and their ability to remain stabilized during use, greatly reducing or potentially eliminating the need to recalibrate these devices during or between experiments.
Unprecedented single-cell studies in virtual embryo
Researchers have created the first complete description of early embryo development, accounting for every single cell in the embryo. This 'virtual embryo' will help to answer how the different cell types in an organism can originate from a single egg cell.
Turning on the 'off switch' in cancer cells
A team of scientists has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer. The discovery marks a critical step toward developing a potential new class of anti-cancer drugs that enhance the activity of a prevalent family of tumor suppressor proteins, the authors say.
Interim Guidance for Implementing Safety Practices for Critical Infrastructure Workers Who May Have Had Exposure to a Person with Suspected or Confirmed COVID-19
Interim Guidance for Implementing Safety Practices for Critical Infrastructure Workers Who May Have Had Exposure to a Person with Suspected or Confirmed COVID-19
Households Living in Close Quarters
This guidance is intended for people living together in close quarters, such as people who share a small apartment, or for people who live in the same household with large or extended families.
Aquaculture at the crossroads of global warming and antimicrobial resistance
Antimicrobial resistance is responsible for some 700,000 deaths each year worldwide. In relation to this phenomenon, researchers have raised the alarm regarding the development of antimicrobial-resistant bacteria in aquaculture, which is affecting fish production and human health worldwide. Their study established for the first time a link between global warming and an increased risk of antimicrobial resistance, and warned against inappropriate use of antibiotics.
Male-female cardiac repair differences in heart failure survival after heart attack
A new study investigated the molecular and cellular processes underlying cardiac repair in male and female mice after a severe heart attack. The researchers discovered that heart repair happened faster in the female mice than the males after heart attack, and that improved survival and delayed cardiac failure.
Support for States, Tribes, Localities and Territories
Support for States, Tribes, Localities and Territories
New decision model shapes strategies for dealing with public health emergencies
The efficient allocation of medical resources can be modelled mathematically. The study, which started a few years before coronavirus appeared, offers timely insights for governments and organizations who are faced with an unprecedented healthcare crisis. Specifically, it presents a comprehensive decision model for optimizing the use of alternative tests and treatments on specific population groups, and suggests that even less-than-perfect tests can help improve effective spending limited healthcare resources.
Unprecedented 3D images of live cells plus details of molecules inside
The insides of living cells can be seen in their natural state in greater detail than ever before using a new technique. This advance should help reveal the complex and fragile biological interactions of medical mysteries, like how stem cells develop or how to deliver drugs more effectively.
Frequently Asked Questions on COVID-19 Testing at Laboratories
Frequently Asked Questions on COVID-19 Testing at Laboratories
Type 2 diabetes: Too much glucagon?
Patients with type 2 diabetes secrete not only too little insulin but also too much glucagon, which contributes to poor blood glucose control.
People may know the best decision -- and not make it
When faced with a decision, people may know which choice gives them the best chance of success, but still take the other option, a new study suggests. People may choose based on a ''gut feeling'', a habit, or what worked for them last time, rather than on what they have learned will work most often.
Electronics that mimic the human brain in efficient learning
Only 10 years ago, scientists working on what they hoped would open a new frontier of neuromorphic computing could only dream of a device using miniature tools called memristors that would function/operate like real brain synapses. But now a team has discovered, while on their way to better understanding protein nanowires, how to use these biological, electricity conducting filaments to make a neuromorphic memristor, or 'memory transistor,' device.
Maternal hypertensive disorders may lead to mental health disorders in children
Hypertensive pregnancy disorders, especially preeclampsia -- may increase the risk of psychological development disorders and behavioral and emotional disorders in children. This is the first study to show that preeclampsia predicts increased offspring risk of any childhood mental disorder, regardless of mental disorders in the parents and other conditions.
воскресенье, 19 апреля 2020 г.
Novel technology aims to improve treatment of neurological diseases
Researchers are developing new 'gene promoters' - which act like switches to turn genes on - for use with gene therapy, the delivery of new genes to replace ones that are faulty. The new promoters work especially well for brain and other neurological disorders and provide longer-lasting functionality compared to other promoters.
Researchers achieve remote control of hormone release
Using magnetic nanoparticles, scientists stimulate the adrenal gland in rodents to control release of hormones linked to stress.
From watching reruns to relationships, there are many ways of feeling connected
New research suggests that non-traditional social strategies, which can include so-called ''guilty pleasures,'' are just as effective at fulfilling critical social needs as family connections, romantic relationships or strong social support systems. The study represents the first time researchers have empirically combined the traditional and non-traditional for comparative purposes to simultaneously test their relative effectiveness.
A key brain region for controlling binge drinking has been found
A team of researchers has found that turning off a stress signaling system in a single specific brain area can reduce harmful binge drinking. This finding brings researchers one step closer to understanding which signals in the brain drive individuals to consume alcohol excessively and put them at risk for developing an alcohol use disorder.
Relying on 'local food' is a distant dream for most of the world
A recent study shows that less than one-third of the world's population could currently meet their demand for food produced in their local vicinity.
Simulations show how to make gene therapy more effective
Diseases with a genetic cause could be treated by supplying a correct version of the faulty gene. However, in practice, delivering new genetic material to human cells is difficult. A promising method for the delivery of such genes involves the use of DNA/lipid complexes (lipoplexes). Scientists have now used advanced simulations to investigate how these lipoplexes deliver DNA fragments into cells. The results can be used to improve their efficiency.
Stem cells in human embryos commit to specialization surprisingly early
The point when human embryonic stem cells irreversibly commit to becoming specialized has been identified by researchers.
Cancer drug resistance study raises immune red flags
Once a cancer patient's tumors develop resistance to chemotherapy, the prognosis can be poor. However, inhibiting a key gene involved in multidrug resistance, MDR1, has not improved outcomes. A new study offers a reason, revealing unintended downstream effects on immune system cells.
Under pressure: New bioinspired material can 'shapeshift' to external forces
Inspired by how human bone and colorful coral reefs adjust mineral deposits in response to their surrounding environments, researchers have created a self-adapting material that can change its stiffness in response to the applied force. This advancement can someday open the doors for materials that can self-reinforce to prepare for increased force or stop further damage.
Nasal smear as an allergy screening test
In the world of allergy diagnostics, the familiar blood samples and unpleasant skin prick procedures for testing allergen tolerance may soon be a thing of the past. A team of researchers has demonstrated that sufficient quantities of allergy antibodies for a diagnosis can be effectively measured in nasal secretions.
New chemical tools can control the concentration of lipids in living cells
So far, it has been difficult to analyze the functions of lipid molecules in living cells. Researchers have now developed chemical tools that can be activated by light and used to influence lipid concentration in living cells. This approach could enable medical doctors to work with biochemists to identify what molecules within a cell do.
Lighting the way to safer heart procedures
In the first study of its kind, researchers provide evidence that an alternative imaging technique could someday replace current methods that require potentially harmful radiation.
Neural circuits mapped: Now we understand vision better
Researchers have discovered the function of a special group of nerve cells which are found in the eye and which sense visual movement. The findings give us a completely new understanding of how conscious sensory impressions occur in the brain.
New universal Ebola vaccine may fight all four virus species that infect humans
Infectious disease scientists report early development of a potential universal vaccine for Ebola viruses that preclinical tests show might neutralize all four species of these deadly viruses infecting people in recent outbreaks, mainly in Africa. Although still in early preclinical testing, researchers report that their data indicate that the prospective vaccine has potential to be a stand-alone protection from Ebola.
COVID-19 Forecasts
State level forecasts show observed and forecasted state level cumulative COVID-19 deaths in the US.
COVID-19 Forecasts for the United States
CDC works with partners to bring together weekly forecasts for COVID-19 deaths in one place. These forecasts have been developed independently and shared publicly. It is important to bring these forecasts together to help understand how they compare with each other and how much uncertainty there is about what may happen in the upcoming four weeks.
What Food and Grocery Pick-up and Delivery Drivers Need to Know about COVID-19
What Food and Grocery Pick-up and Delivery Drivers Need to Know about COVID-19
What Rideshare, Taxi, Limo, and other Passenger Drivers-for-Hire Need to Know about COVID-19
What Rideshare, Taxi, Limo, and other Passenger Drivers-for-Hire Need to Know about COVID-19
COVID-19 Infection Prevention and Control in Healthcare Settings: Questions and Answers
Information supports healthcare personnel who may care for patients who are confirmed with or under investigation for COVID-19.
суббота, 18 апреля 2020 г.
Mysterious tuft cells found to play role in pancreatitis
Scientists have uncovered the formation of tuft cells during pancreatitis and the surprising role of these cells in immunity, using mouse models of pancreatitis. The findings could lead to the development of new biomarkers to test for pancreatitis and pancreatic cancer.
Micro-device to detect bacteria, viruses
Scientists designed a next-generation miniature lab device that uses magnetic nano-beads to isolate minute bacterial particles that cause diseases. This new technology improves how clinicians isolate drug-resistant strains of bacterial infections and difficult-to-detect micro-particles such as those making up Ebola and coronaviruses.
пятница, 17 апреля 2020 г.
Genomics used to estimate Samoan population dynamics over 3,000 years
A new study estimating the size of the Samoan population using contemporary genomic data found that the founding population remained low for the first 1,500 years of human settlement, contributing to understanding the evolutionary context of the recent rise in obesity and related diseases.
Peer-review: Modernizing a time-intensive process
Astronomer have found that a new process of evaluating proposed scientific research projects is as effective -- if not more so -- than the traditional peer-review method.
четверг, 16 апреля 2020 г.
New clues to predict the risks astronauts will face from space radiation on long missions
Researchers used a novel approach to test assumptions in a model used by NASA to predict health risks for astronauts.
How exercise supports your mental fitness: Current recommendations
Sporting activities can bring about a long-term improvement in cognitive performance across all age groups. However, the effects differ between men and women, and not all sports provide the same impact. Researchers have provided recommendations based on a comprehensive analysis of previous studies.
New 'toolbox' for urological cancer detection
Researchers have developed a new method for biomarker discovery of urological cancers. The method enables timely diagnosis and treatment of cancer. Urological cancers include e.g. prostate, bladder and kidney cancers.
Importance of mitochondrial small proteins in energy production
A small mitochondrial protein is necessary for energy production and its malfunction could be behind a range of degenerative diseases, according to new study.
Insight into the synapses
'Distance keeping' is not exactly the motto of the glutamate receptors: Using super-resolution microscopy, it now was discovered that the receptors usually appear in small groups at the synapses and are in contact with other proteins.
Genetic variation not an obstacle to gene drive strategy to control mosquitoes
New research from entomologists clears a potential obstacle to using CRISPR-Cas9 'gene drive' technology to control mosquito-borne diseases such as malaria, dengue fever, yellow fever and Zika.
Scents regulate fat storage without affecting eating behavior
Researchers discovered that, in the lab worm C. elegans, certain scents dynamically regulate fat mobilization by interacting with specific olfactory neurons through specific receptors.
Solving the puzzle of Mitchell disease
Researchers discovered that ACOX1 is involved in two distinct neurodegenerative disorders.
Study finds evidence for existence of elusive 'metabolon'
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or 'metabolons,' in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers, for the first time, have directly observed functional metabolons involved in generating purines, the most abundant cellular metabolites. The findings could lead to the development of novel therapeutic strategies that disrupt the progression of cancer.
Researchers get important glimpse into microbiome development in early life
A team of researchers has characterized how the gut microbiome develops in the first hours of infancy, providing a critical baseline for how changes in this environment can impact health and disease later in life.
Whole genome sequencing reveals genetic structural secrets of schizophrenia
Scientists have conducted the largest-ever whole genome sequencing study of schizophrenia to provide a more complete picture of the role the human genome plays in this disease.
A non-invasive way of monitoring diabetes
Saliva could be used instead of blood to monitor diabetes in a new method.
Treatment for spasticity in mice, following spinal cord injuries discovered
In experiments with mice, researchers have studied neuronal mechanisms and found a way to by and large prevent spasticity from developing after spinal cord injuries. A new study shows that the researchers have done this by using already approved medicine for high blood pressure.
Psychedelic compound from magic mushrooms produced in yeast
Scientists prove that psilocybin, a potential drug for treating depression and other psychological conditions can be produced in yeast.
Proteins may halt the severe cytokine storms seen in COVID-19 patients
A team of researchers has developed specialized antibody-like receptor proteins that they believe could soak up the excess cytokines produced during a cytokine storm. This excessive immune response, sometimes seen in Covid-19 patients, can be fatal.
Could shrinking a key component help make autonomous cars affordable?
A team led by Stanford electrical engineer Jelena Vuckovic is working on shrinking the mechanical and electronic components in a rooftop lidar down to a single silicon chip that she thinks could be mass produced for as little as a few hundred dollars.
Genetics linked to childhood emotional, social and psychiatric problems
Emotional, social and psychiatric problems in children and adolescents have been linked to higher levels of genetic vulnerability for adult depression.
Influenza: researchers show that new treatment reduces spread of virus
Researchers have shown that a new antiviral drug for influenza can treat the infection at the same time as reducing the risk of transmission to others, offering powerful potential to change the way we manage influenza outbreaks -- particularly in vulnerable groups.
What is an individual? Information Theory may provide the answer
Despite the near-universal assumption of individuality in biology, there is little agreement about what individuals are and few rigorous quantitative methods for their identification. A new approach may solve the problem by defining individuals in terms of informational processes.
Lung-heart super sensor on a chip tinier than a ladybug
This Lilliputian chip's detection bandwidth is enormous -- from sweeping body motions to faint sounds of the heartbeat, pulse waves traversing body tissues, respiration rate, and lung sounds.
Bile metabolite of gut microbes boosts immune cells
A new study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.
Aspirin linked to reduction in risk of several cancers of the digestive tract
The largest and most comprehensive analysis to date of the link between aspirin and cancers of the digestive tract has shown that it is associated not only with a significant reduction in the risk of developing bowel cancer but also of several other cancers that almost invariably fatal, such as pancreatic and liver cancers.
Obesity is a critical risk factor for type 2 diabetes, regardless of genetics
Obesity increases the risk of developing type 2 diabetes by at least 6 times, regardless of genetic predisposition to the disease.
Low-cost imaging system poised to provide automatic mosquito tracking
Mosquito-transmitted diseases such as malaria, dengue and yellow fever are responsible for hundreds of thousands of deaths every year. A new low-cost imaging system could make it easier to track mosquito species that carry disease, enabling a more timely and targeted response.
Prescribing an overdose: A chapter in the opioid epidemic
Research indicates that widespread opioid overprescribing contributed to the opioid epidemic. New research shows that this dangerous trend has apparently been coupled with another: inappropriate use of high-potency opioids.
Подписаться на:
Комментарии (Atom)