CDC is aggressively responding to the global outbreak of COVID-19 and preparing for the potential of community spread in the United States.
воскресенье, 31 мая 2020 г.
суббота, 30 мая 2020 г.
Benefits of social networks to disaster response questioned
Faced with a common peril, people delay making decisions that might save lives, fail to alert each other to danger and spread misinformation. Those may sound like behaviors associated with the current pandemic, but they actually surfaced in experiments on how social networks function in emergencies.
The fight goes on: Clinical trial shows promising new treatment for rare blood cancer
Although lymphoma is one of the most common types of blood cancer, it has a rare subtype for which no effective treatment regimens are known. For the first time, researchers have conducted clinical trials for a new treatment protocol and report it to be quite promising.
Key player in hepatitis A virus infection
Researchers designed experiments using gene-editing tools to discover how molecules called gangliosides serve as de facto gatekeepers to allow the virus entry into liver cells and trigger disease.
Adolescent exposure to anesthetics may cause alcohol use disorder, new research shows
Early exposure to anesthetics may make adolescents more susceptible to developing alcohol use disorder (AUD), according to new research.
'Single pixel' vision in fish helps scientists understand how humans can spot tiny details
Recently discovered 'single-pixel vision' in fish could help researchers understand how humans are able to spot tiny details in their environment -- like stars in the sky.
Study charts developmental map of inner ear sound sensor in mice
A team of researchers has generated a developmental map of a key sound-sensing structure in the mouse inner ear. Scientists analyzed data from 30,000 cells from mouse cochlea, the snail-shaped structure of the inner ear. The results provide insights into the genetic programs that drive the formation of cells important for detecting sounds and the underlying causes for some forms of inner ear hearing loss.
пятница, 29 мая 2020 г.
Fearful Great Danes provide new insights to genetic causes of fear
Researchers have identified a new genomic region and anxiety-related candidate genes associated with fearfulness in dogs. Findings support their hypothesis that fearfulness and anxiety are hereditary traits in dogs, and there may be shared factors underlying anxiety in both humans and dogs.
How toxic protein spreads in Alzheimer's disease
Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer's disease. A new study shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.
Anesthesia's effect on consciousness solved, settling century-old scientific debate
How does general anesthesia cause loss of consciousness? Despite its 175-year-history of use by the U.S. medical system, science has been unable to definitively answer that question, until now. The lipid-based answer could open other brain mysteries.
Solution to century-old math problem could predict transmission of infectious diseases
An academic has achieved a milestone in statistical/mathematical physics by solving a 100-year-old physics problem -- the discrete diffusion equation in finite space.
Meat and Poultry Processing Facility Assessment Toolkit
Tools and resources for occupational safety and health professionals and state and local public health officials assessing meat and poultry processing facilities.
Anuncios de servicio público (PSA, por sus siglas en inglés)
Anuncios de servicio público (PSA, por sus siglas en inglés)
New method to map cholesterol metabolism in brain
Researchers have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new treatments.
Wildfires can alter Arctic watersheds for 50 years
Climate change has contributed to the increase in the number of wildfires in the Arctic and can dramatically shift stream chemistry. Researchers at the University of New Hampshire have found that some of the aftereffects, like decreased carbon and increased nitrogen, can last up to five decades and could have major implications on vital waterways like the Yenisei River and the Arctic Ocean
New technology enables fast protein synthesis
Chemists have developed a protocol to rapidly produce protein chains up to 164 amino acids long. The flow-based technology could speed up drug development and allow scientists to design novel protein variants incorporating amino acids that don't occur naturally in cells.
Gold mining with mercury poses health threats for miles downstream
Small-scale gold mining in the Peruvian Amazon poses a health hazard not only to the miners and communities near where mercury is used to extract gold from ore, but also to downstream communities hundreds of kilometers away where people eat mercury-contaminated river fish as part of their diet. Downstream children under 12 with the highest levels of mercury in their bodies were found to have lost IQ points and become anemic.
Researchers identify mechanisms that make skin a protective barrier
A research team has identified one of the mechanisms that establish the skin as a protective barrier, a breakthrough that is critical to understanding and treating common skin conditions including eczema and psoriasis, according to a new study.
Using riboflavin, UV light reduces SARS-CoV-2 pathogens in plasma, whole blood
Researchers used existing technologies to show that exposing the coronavirus to riboflavin and ultraviolet light reduces blood-borne pathogens in human plasma and whole-blood products.
Growing evidence that minority ethnic groups in England may be at higher risk of COVID-19
Evidence available to date suggests that minority ethnic groups in England, particularly black and south Asian people, may be at increased risk of testing positive for Covid-19, compared to people from white British backgrounds, according to a new study.
'Watcher' tracks coronavirus in Cincinnati and beyond
As cases of COVID-19 soar, two University of Cincinnati students develop an interactive dashboard that shows cases and deaths related to the novel coronavirus throughout the nation.
New model predicts the peaks of the COVID-19 pandemic
Researchers describe a single function that accurately describes all existing available data on active COVID-19 cases and deaths -- and predicts forthcoming peaks.
Frequently Asked Questions and Answers: Coronavirus Disease-2019 (COVID-19) and Children
Most confirmed cases of COVID-19 reported from China have occurred in adults.
New gut-brain link: How gut mucus could help treat brain disorders
Gut bacterial imbalance is linked with many neurological disorders. Now researchers have identified a common thread: changes in gut mucus. It's a new gut-brain connection that opens fresh paths for scientists searching for ways to treat brain disorders by targeting our 'second brain' -- the gut.
Survey identifies learning opportunities related to health impacts of climate change
An international survey of Global Consortium on Climate and Health Education (GCCHE) membership found that the majority of members -- health professions schools and programs, including medical, nursing, and public health -- offer learning opportunities related to the health impacts of climate change, yet many also encountered challenges in instituting or developing curricula. The results of the survey provide a baseline assessment of the state of climate-health education internationally among health professions institutions.
Considerations When Preparing for COVID-19 in Assisted Living Facilities
Considerations When Preparing for COVID-19 in Assisted Living Facilities
Discontinuation of Home Isolation for Persons with COVID-19 (Interim Guidance)
Limited information is available to characterize the spectrum of clinical illness, transmission efficiency, and the duration of viral shedding for persons with novel coronavirus disease (COVID-19). This guidance is based on available information about COVID-19 and subject to change as additional information becomes available.
Communication Toolkit for Airlines to inform Travelers and Crew
Communication Toolkit for Airlines to inform Travelers and Crew
United States Coronavirus (COVID-19) Death Toll Surpasses 100,000
Today the number of people in the United States who have died from COVID-19 surpassed 100,000. Families, friends, coworkers, loved ones and community members are grieving for each person who has been lost to this disease.
Restoring nerve-muscle communication in ALS
A new study finds that restoring the protein SV2 in a genetic form of ALS can correct abnormalities in transmission and even prevent cells from dying, providing a new target for future therapies.
Molecular effects of exercise detailed
A simple blood test may be able to determine how physically fit you are, according to a new study.
Users of high-potency cannabis four times more likely to report associated problems
Users of high-potency cannabis are four times more likely to report associated problems, and twice as likely to report anxiety disorder, than users of lower-potency strains, according to new research.
Beyond the garnish: Will a new type of produce get the microgreen light?
Microgreens. They're leafy green vegetables that are relatively new to the dining room, but a new study indicates that they will be welcome company at the table.
четверг, 28 мая 2020 г.
Antibody Testing At-A-Glance Recommendations for Professionals
Antibody Testing At-A-Glance Recommendations for Professionals
Guidance for Direct Service Providers, Caregivers, Parents, and People with Developmental and Behavioral Disorders
This guidance is intended to inform Direct Service Providers, caregivers, parents, and people with developmental and behavioral disorders on accommodations, modifications, and assistance related to COVID-19 preparation and response.
People with Developmental and Behavioral Disorders
People with Developmental and Behavioral Disorders
Key components of proteins are twisted to boost reactions useful to medicine
In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity or alkalinity. Certain medicines make use of reactions involving amide bonds, but the bonds are so strong they actually slow down reactions, impeding the effectiveness of the medicines. Researchers devised a way to modify amide bonds with a twist to their chemical structure that speeds up reactions by 14 times.
Low vaccination rates and 'measles parties' fueled 2019 measles outbreak in NYC
An analysis of the 2018-2019 measles outbreak in New York City identifies factors that made the outbreak so severe: delayed vaccination of young children combined with increased contact among this age group, likely through 'measles parties' designed to purposely infect children.
Domestic violence reports on the rise as COVID-19 keeps people at home, study shows
Researchers have found an increase in domestic violence reports in Los Angeles and Indianapolis since the stay-at-home restrictions were implemented in March.
Guidance for Direct Service Providers
CDC has published guidance to support Direct Service Providers (DSPs), including personal care attendants, direct support professionals, paraprofessionals, therapists, and others as they support people with disabilities for COVID-19.
Previously claimed memory boosting font 'Sans Forgetica' does not actually boost memory
It was previously claimed that the font Sans Forgetica could enhance people's memory for information, however researchers have found after carrying out numerous experiments that the font does not enhance memory.
Standard Operating Procedure (SOP) for Triage of Suspected COIVD-19 Patients in non-US Healthcare Settings
Standard Operating Procedure (SOP) for Triage of Suspected COIVD-19 Patients in non-US Healthcare Settings
Information for Sanitation and Wastewater Workers on COVID-19
Informational web page with links to provide relevant COVID-19 information for sanitation and wastewater workers
Screening clients for respiratory infection symptoms at entry to homeless shelters
Screening clients for respiratory infection symptoms at entry to homeless shelters
Considerations for Pharmacies during the COVID-19 Pandemic
Considerations for Pharmacies during the COVID-19 Pandemic
COVID-19 Forecasts for the United States
CDC works with partners to bring together weekly forecasts for COVID-19 deaths in one place. These forecasts have been developed independently and shared publicly. It is important to bring these forecasts together to help understand how they compare with each other and how much uncertainty there is about what may happen in the upcoming four weeks.
Guidance for Group Homes for Individuals with Disabilities
CDC has guidance for administrators of group homes (GHs) for people with disabilities. GH administrators may consider implementing several strategies to encourage behaviors that reduce the spread of COVID-19.
Sugars could be the key to an earlier, more accurate test for prostate cancer
A new type of test that uses complex sugars to detect prostate cancer earlier and with greater accuracy.
Interim Additional Guidance for Outpatient and Ambulatory Care Settings: Responding to Community Transmission of COVID-19 in the United States
Interim Additional Guidance for Outpatient and Ambulatory Care Settings: Responding to Community Transmission of COVID-19 in the United States
New technique offers higher resolution molecular imaging and analysis
A new approach could help researchers understand more complicated biomolecular interactions and characterize cells and diseases at the single-molecule level.
The death marker protein cleans up your muscles after exercise
Researchers have demonstrated that physical activity prompts a clean-up of muscles as the protein ubiquitin tags onto worn-out proteins, causing them to be degraded. This prevents the accumulation of damaged proteins and helps keep muscles healthy.
Human growth hormone treatment after ACL injury may prevent loss of muscle strength
A new study finds the use of HGH treatment in patients that have undergone ACL reconstructive surgery may prevent the loss of muscle strength and weakness.
Exploring the use of 'stretchable' words in social media
An investigation of Twitter messages reveals new insights and tools for studying how people use stretched words, such as 'duuuuude,' 'heyyyyy,' or 'noooooooo.'
среда, 27 мая 2020 г.
Exposure to 'good bacteria' during pregnancy buffers risk of autism-like syndrome
Giving beneficial bacteria to stressed mothers during the equivalent of the third trimester of pregnancy prevents an autism-like disorder in their offspring, according to a new animal study.
New understanding of RNA movements can be used to treat cancer
New research shows that an RNA molecule involved in preventing tumor formation can change its structure and thereby control protein production in the cell. The finding can have important clinical implications as it opens for new strategies to treat different types of cancer.
New linguistic findings on the prevalence of 'LOL'
A new study involving a scientific analysis of the prevalence of 'LOL' in students' text messages demonstrates important potential applications for classroom learning.
вторник, 26 мая 2020 г.
Evidence shows cloth masks may help against COVID-19
Researchers examined a century of evidence including recent data, and found strong evidence showing that cloth and cloth masks can reduce contamination of air and surfaces.
Remdesivir for COVID-19 improves time to recovery, peer-reviewed data shows
Remdesivir is superior to the standard of care for the treatment of COVID-19, according to a preliminary analysis based on data from a randomized, controlled trial. Researchers found that the antiviral was most beneficial for hospitalized patients with severe disease who required supplemental oxygen.
Public disclosure of COVID-19 cases is more effective than lockdowns, study shows
New research shows South Korea's tech and privacy laws effectively protect the vulnerable while preserving economic stability during the pandemic.
Dementia gene raises risk of severe COVID-19
Having a faulty gene linked to dementia doubles the risk of developing severe COVID-19, according to a large-scale study.
Data Management for Assigning and Managing Investigations
Data Management for Assigning and Managing Investigations
Evaluating Case Investigation and Contact Tracing Success
Evaluating Case Investigation and Contact Tracing Success
Interim Guidance on Developing a COVID-19 Case Investigation & Contact Tracing Plan: Overview
Interim Guidance on Developing a COVID-19 Case Investigation & Contact Tracing Plan: Overview
Scaling Up Staffing Roles in Case Investigation and Contact Tracing
Scaling Up Staffing Roles in Case Investigation and Contact Tracing
When to Initiate Case Investigation and Contact Tracing Activities
When to Initiate Case Investigation and Contact Tracing Activities
Beware of false negatives in diagnostic testing of COVID-19
Researchers have found that the chance of a false negative result -- when a virus is not detected in a person who actually is, or recently has been, infected -- is greater than 1 in 5 and, at times, far higher.
Countering COVID-19 impacts on children from low-income households
The COVID-19 pandemic has magnified the social, educational and health care disparities already plaguing the nearly 40 million Americans the US Census Bureau estimates are living in poverty. Perhaps the hardest hit members of that population, say pediatricians, are children from low-income households.
New drug combination being tested to conquer COVID-19
Researchers hope giving Remdesivir along with a powerful anti-inflammatory could be the key to treating the most severe COVID-19 cases.
Can copying your friends help you achieve your goals?
Consumers often struggle to achieve self-set life improvement goals, but what if deliberately emulating the successful strategies used by their friends could help them?
High-strain exercise linked to very early pregnancy loss
In women with a history of miscarriage, higher levels of physical activity were associated with a greater risk of subclinical, or very early, pregnancy loss, according to new research. Among women with confirmed pregnancy, physical activity and miscarriage risk were unrelated.
Running Essential Errands
As communities across the United States take steps to slow the spread of COVID-19 by limiting close contact, people are facing new challenges and questions about how to meet basic household needs, such as buying groceries and medicine, and completing banking activities. The following information provides advice about how to meet these household needs in a safe and healthy manner.
Immune molecule's complex role in Huntington's disease
Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice and affects neural connection genes, a new study finds.
How a protein can inhibit cancer development in mice
In a new study, researchers have discovered how the protein PP2A can inhibit tumor growth in mice. The protein turns off an enzyme that stimulates cell growth, thus inhibiting the development of cancer.
Novel electric impulses relieve the pain
Chronic pain can be reduced by stimulating the vagus nerve in the ear with electrodes. In a microanatomic study, the human ear has now been analyzed on a micrometer scale. A computer model was created, allowing scientists to find optimal spots and optimal pulse shapes for electric stimulation. The results have now been successfully tested on patients.
Similar to humans, chimpanzees develop slowly
Researchers have systematically investigated developmental milestones in wild chimpanzees of the Taï National Park (Ivory Coast) and found that they develop slowly, requiring more than five years to reach key motor, communication and social milestones. This timeframe is similar to humans, suggesting slow maturation of the brain.
A child's brain activity reveals their memory ability
A child's unique brain activity reveals how good their memories are, according to new research.
Unique insight into development of the human brain: Model of the early embryonic brain
Stem cell researchers have designed a model of an early embryonic brain. The model will increase our understanding of how the human brain develops and can thereby help to accelerate the development of stem cell treatments for brain disorders such as Parkinson's disease, epilepsy and dementia.
A new law in laser physics could make eye surgery simpler
Revisiting simple soliton lasers and their relationship to light dispersion has allowed scientists to ramp up their power. They hope these quartic-soliton lasers could have uses in eye and heart surgery and in the engineering of delicate materials.
Women with Neanderthal gene give birth to more children
One in three women in Europe inherited the receptor for progesterone from Neanderthals -- a gene variant associated with increased fertility, fewer bleedings during early pregnancy and fewer miscarriages.
Increased usability and precision in vascular imaging
Researchers have developed a new X-ray contrast agent. The contrast agent is easier to use and distributes into all blood vessels more reliably, increasing the precision of vascular imaging. This reduces the number of animals required in research experiments.
Even natural products can be harmful for the unborn child
Plant products ingested by pregnant women through their diet are broken down by the intestinal microbiota into chemical substances, some of which can cross the placental barrier and reach the fetus. These foreign substances can harm the unborn child, even if they are of 'natural origin'.
New approach to some mental disorders
Depression, anxiety and PTSD might not be disorders at all, according to biological anthropologists. In the paper, the researchers propose a new approach to mental illness that would be informed by human evolution, noting that modern psychology, and in particular its use of drugs like antidepressants, has largely failed to reduce the prevalence of mental disorders.
Rejuvenated fibroblasts can recover the ability to contract
A recent study has shown that rejuvenated fibroblasts can recover their ability to self-contract. This encouraging discovery holds great potential for applications in regenerative medicine and stem cell engineering.
New method reveals where DNA is at risk in the cell
Researchers have developed a new sequencing method that makes it possible to map how DNA is spatially organized in the cell nucleus -- revealing which genomic regions are at higher risk of mutation and DNA damage.
Inexpensive retinal diagnostics via smartphone
Retinal damage due to diabetes is now considered the most common cause of blindness in working-age adults. In low- and middle-income countries, an eye examination via smartphone could help to detect changes at an early stage.
Babies know when you imitate them -- and like it
Six-month old infants recognize when adults imitate them, and perceive imitators as more friendly, according to a new study. The babies looked and smiled longer at an adult who imitated them, as opposed to when the adult responded in other ways. Babies also approached them more, and engaged in imitating games.
Travelers Prohibited from Entry to the United States
Travelers Prohibited from Entry to the United States
понедельник, 25 мая 2020 г.
Problems with alcohol? 29 gene variants may explain why
A genome-wide analysis of more than 435,000 people has identified 29 genetic variants linked to problematic drinking, researchers report.
Interim Guidance for Administrators of US Institutions of Higher Education
Institutions of higher education (IHE), working together with local health departments, have an important role in slowing the spread of diseases, and protecting vulnerable students, staff, and faculty to help ensure a safe and healthy learning environment.
New double-contrast technique picks up small tumors on MRI
Early detection of tumors is extremely important in treating cancer. A new technique offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue.
Evaluating and Reporting Persons Under Investigation (PUI)
Evaluating and Reporting Persons Under Investigation (PUI)
Immunity to coronaviruses: What do we know so far?
A new article discusses the existing knowledge about immune responses to SARS-CoV-2 and other coronaviruses, and how this could be used to inform virus control strategies.
Study reveals first evidence inherited genetics can drive cancer's spread
Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. New research implicates own pre-existing genetics.
Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens from Persons for Coronavirus Disease 2019 (COVID-19)
Health care providers should contact their local/state health department immediately to notify them of patients with fever and lower respiratory illness who they suspect may have COVID-19.
воскресенье, 24 мая 2020 г.
High stress related to coronavirus is the new normal for many parents, says new APA survey
Nearly half of parents of children under age 18 say their stress levels related to the coronavirus pandemic are high, with managing their kids' online learning a significant source of stress for many, according to a new survey by the American Psychological Association.
Social isolation linked to more severe COVID-19 outbreaks
Regions of Italy with higher family fragmentation and a high number of residential nursing homes experienced the highest rate of COVID-19 infections in people over age 80, according to a new study.
Patients with COVID-19 may develop thyroid infection
COVID-19 infection may cause subacute thyroiditis, according to a new case study.
Stroke rates among COVID-19 patients are low, but cases are more severe
The rate of strokes in COVID-19 patients appears relatively low, but a higher proportion of those strokes are presenting in younger people and are often more severe compared to strokes in people who do not have the novel coronavirus, while globally rates for stroke hospitalizations and treatments are significantly lower than for the first part of 2019, according to new research.
A replaceable, more efficient filter for N95 masks
Researchers have developed a membrane that can be attached to a regular N95 mask and replaced when needed. The filter has a smaller pore size than normal N95 masks, potentially blocking more virus particles.
Higher fiber saves lives, but food processing may remove benefits
Eating more fiber can improve life expectancy for those with diabetes, researchers say. Type 2 diabetes has reached epidemic proportions worldwide, is associated with serious medical complications, and increases the risk of dying from COVID-19.
No evidence blanket 'do-not-resuscitate' orders for COVID-19 patients are necessary; investigators urge caution
It's inappropriate to consider blanket do-not-resuscitate orders for COVID-19 patients because adequate data is not yet available on US survival rates for in-hospital resuscitation of COVID-19 patients and data from China may not relate to US patients, according to a new article.
New technology can detect anti-virus antibody in 20 minutes
Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a suitable reagent is developed, this technology could be used to detect antibodies against SARS-CoV-2, the causative virus of COVID-19.
If You Are Sick
If you are sick with COVID-19 or suspect you are infected with the virus that causes COVID-19, you should take steps to help prevent the disease from spreading to people in your home and community.
FAQs for Administrators and Leaders at Community- and Faith-Based Organizations
FAQs for Administrators and Leaders at Community- and Faith-Based Organizations
Get Your Community- and Faith-Based Organizations Ready for Coronavirus Disease 2019
This interim guidance is to help community- and faith-based organizations (CFBOs), whose members may include vulnerable populations, plan for community transmission of coronavirus disease (COVID-19) in the United States.
Information for Laboratories
This page includes interim guidance and resources for laboratory professionals working with specimens from persons under investigation (PUI) for coronavirus disease 2019 (COVID-19).
Blood flow recovers faster than brain in micro strokes
Neurobiologists show that increased blood flow to the brain is not an accurate indicator of neuronal recovery after a microscopic stroke.
Cell reproduction dogma challenged
Meiosis is essential to sexual reproduction. For almost 15 years, it has been commonly held that retinoic acid, a molecule derived from vitamin A, triggers meiosis in mammalian germ cells. Yet new research demonstrates that meiosis in mice begins and proceeds normally even in the absence of retinoic acid. These findings set the stage for new research in the field of reproductive biology.
суббота, 23 мая 2020 г.
About Cloth Face Coverings
COVID-19 spreads mainly from person to person through respiratory droplets produced when an infected person coughs, sneezes, or talks. These droplets can land in the mouths or noses of people who are nearby or possibly be inhaled into the lungs.
How to Wear Cloth Face Coverings
Cloth face coverings are an additional step to help slow the spread of COVID-19 when combined with every day preventive actions and social distancing in public settings.
How to Wash Cloth Face Coverings
Cloth face coverings should be washed after each use. It is important to always remove face coverings correctly and. Wash your hands after handling or touching a used face covering.
Towable sensor free-falls to measure vertical slices of ocean conditions
Towable sensor free-falls to measure vertical slices of ocean conditions.
Use of Cloth Face Coverings to Help Slow the Spread of COVID-19
Use of Cloth Face Coverings to Help Slow the Spread of COVID-19
пятница, 22 мая 2020 г.
Key Information to Collect During a Case Interview
Key Information to Collect During a Case Interview
A 'switch' that turns autoimmunity drugs into powerful anti-cancer treatments
Scientists have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular 'switch'.
Sex bias in pain research
Most pain research remains overwhelmingly based on the study of male rodents, continuing to test hypotheses derived from earlier experiments on males. This points to an important blind spot in pain research, particularly as it relates to advancing research into new pain medications.
New urine testing method holds promise for kidney stone sufferers
An improved urine-testing system for people suffering from kidney stones inspired by nature may enable patients to receive results within 30 minutes instead of the current turnaround time of a week or more.
New mobile health tool measures hemoglobin without drawing blood
Researchers have developed a way to use smartphone images of a person's eyelids to assess blood hemoglobin levels. The ability to perform one of the most common clinical lab tests without a blood draw could help reduce the need for in-person clinic visits, make it easier to monitor patients who are in critical condition, and improve care in low- and middle-income countries where access to testing laboratories is limited.
Scientists find evidence of link between diesel exhaust, risk of Parkinson's
A new study in zebrafish identified the process by which air pollution can damage brain cells, potentially contributing to Parkinson's disease.
The self-synthesizing ribosome
As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything from understanding how life develops to designing new methods of drug production.
Surging numbers of first-generation learners being left behind in global education
'First-generation learners' -- a substantial number of pupils around the world who represent the first generation in their families to receive an education - are also significantly more likely to leave school without basic literacy or numeracy skills, a study suggests.
Unconscious: 'Sniff test' predicts recovery of consciousness
If an unconscious person responds to smell through a slight change in their nasal airflow pattern -- they are likely to regain consciousness. This is the conclusion from a new study.
New insight into allergies could improve diagnosis and treatment
Results from a new study may help to improve the diagnosis and treatment of allergies, pointing to a potential marker of these conditions and a new therapeutic strategy.
T-cells could be made into better cancer killers by increasing their protein production
Researchers have developed a technique to quantify protein production in immune cells known as T-cells, which typically target and kill cancer cells. However, when near a tumor, most T cells produce little protein and lose their cancer-fighting ability, and the new technique could help clarify why. Interventions could then be developed to restore protein production and allow T cells in the vicinity of tumors to become better cancer killers.
Steps Healthcare Facilities Can Take Now to Prepare for Coronavirus Disease 2019 (COVID-19)
Steps that healthcare facilities can take to prepare for an outbreak of coronavirus disease (COVID-19) among patients and staff.
Get Your Clinic Ready for Coronavirus Disease 2019 (COVID-19)
Get ready! Steps you take to prepare your clinic for flu also can help protect your patients and healthcare workers from COVID-19.
Placentas from COVID-19-positive pregnant women show injury
In the largest study to examine health of placentas in women who tested positive for COVID-19, findings show placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth.
No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 patients, study finds
A new study finds that the use of chloroquine or hydroxychloroquine is linked to increased rates of mortality and heart arrhythmias among hospital patients with COVID-19. The authors suggest that these drug regimens should not be used to treat COVID-19 outside of clinical trials and urgent confirmation from randomised clinical trials is needed.
First human trial of COVID-19 vaccine finds it is safe and induces rapid immune response
A study of 108 adults finds that the vaccine produced neutralizing antibodies and T-cell response against SARS-CoV-2, but further research is needed to confirm whether the vaccine protects against SARS-COV-2 infection.
Algal genome provides insights into first land plants
Cornell researchers have sequenced and analyzed the genome of a single-celled alga that belongs to the closest lineage to terrestrial plants and provides many clues to how aquatic plants first colonized land.
Brain's 'updating mechanisms' may create false memories
New research is one of the first comprehensive characterizations of poorly formed memories and may offer a framework to explore different therapeutic approaches to fear, memory and anxiety disorders. It may also have implications for accuracy of some witness testimony.
четверг, 21 мая 2020 г.
Rodent Control
Environmental health practitioners and rodent control programs: rodent activity is increasing in some jurisdictions. Rodent control and surveillance are critical for protecting public health during responses to natural disasters and public health emergencies. Learn how to address community-wide rodent activity in your area.
Preventing 'cytokine storm' may ease severe COVID-19 symptoms
A clinical trial in people with the new coronavirus is testing a drug that may halt an overactive immune response before it ramps up.
Heating poppy seeds, but not baking them in muffins, reduces opiate levels
You might have heard the advice to avoid eating a poppy seed bagel or muffin before a drug screen, lest you test positive for opiates. This urban legend is rooted in truth because the tiny black seeds contain small amounts of morphine and codeine that can show up in a drug test. Now, researchers have studied how different treatments affect levels of opiates in poppy seeds.
Inspiring stories from women like themselves helped these moms improve their diet
When researchers asked prospective study participants who they would like to see in videos promoting healthy lifestyle behaviors, the answer was unequivocal: They wanted to see themselves -- that is, other mothers living in low-income households who were overweight or obese. The researchers obliged. And the intervention they designed produced the desired results when it came to improving participants' diet.
Obesity not related to how close you live to fast food or gyms
A new study has shown no correlation between obesity and how close you live to fast food restaurants or gyms. Studies from other countries have previously indicated that these factors may be important in adult obesity.
Measuring blood damage
Red blood cells sometimes rupture when blood is sent through faulty equipment, such as a dialysis machine. This is called hemolysis. Hemolysis also can occur during blood work when blood is drawn too quickly through a needle, leading to defective laboratory samples. Researchers have now developed a method to monitor blood damage in real-time.
Adding a blend of spices to a meal may help lower inflammation
Researchers found that adding six grams of spices to a meal high in fat and carbohydrates resulted in lower inflammation markers hours later.
Legal cannabis hemp oil effectively treats chronic neuropathic pain
Researchers examine the effectiveness of consuming hemp oil extracted from the whole cannabis plant using a chronic neuropathic pain animal model. Researchers showed that legal cannabis hemp oil reduced mechanical pain sensitivity 10-fold for several hours in mice with chronic post-operative neuropathic pain.
Communication Toolkit for Transportation Partners to Inform Road Travelers
Communication Toolkit for Transportation Partners to Inform Road Travelers
Scientists identify gene linked to thinness that may help resist weight gain
Researchers used a genetic database of more than 47,000 people in Estonia to identify a gene linked to thinness that may play a role in resisting weight gain in metabolically healthy thin people. They show that knocking out this gene results in thinner flies and mice and find that expression of it in the brain may be involved in regulating energy expenditure.
Environmental contaminants alter gut microbiome, health
The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants. Scientists review the research linking dozens of environmental chemicals to changes in the gut microbiome and associated health challenges.
Genetic barcodes can ensure authentic DNA fingerprints
Engineers have demonstrated a method for ensuring that an increasingly popular method of genetic identification called ''DNA fingerprinting'' remains secure against inadvertent mistakes or malicious attacks in the field. The technique relies on introducing genetic ''barcodes'' to DNA samples as they are collected and securely sending information crucial to identifying these barcodes to technicians in the laboratory.
When is reading your partner's emotions beneficial, and when harmful?
Are you good at reading your partner's emotions? Your perceptiveness may very well strengthen your relationship. Yet when anger or contempt enter the fray, little is to be gained and the quality of your relationship tanks, researchers found.
Key Strategies to Prepare for COVID-19 in Long-term Care Facilities (LTCFs)
Key Strategies to Prepare for COVID-19 in Long-term Care Facilities (LTCFs)
Parents with degrees give their children significant advantage in math
Children of parents with a degree are almost a year of schooling ahead in math by the age 11 than peers whose parents have just GCSEs, a new study has discovered.
Not all multiple sclerosis-like diseases are alike
Scientists say some myelin-damaging disorders have a distinctive pathology that groups them into a unique disease entity.
Hearts that drum together beat together
Researchers have found that in a structured group drumming task aspects of participants' heart function synchronized. In a subsequent improvisational drumming task, groups with high physiological synchrony in the structured task showed more coordination in drumming. The data show that behavioral synchronization and enhanced physiological synchronization while drumming each uniquely predicts a heightened experience of group cohesion. Additionally, higher physiological synchrony predicts enhanced group performance in a subsequent, different group task.
среда, 20 мая 2020 г.
Identify the Primary Components of COVID-19 Case Investigation and Contact Tracing
Identify the Primary Components of COVID-19 Case Investigation and Contact Tracing
Identify Time Management Practices for Case Investigation and Contact Tracing Leads
Identify Time Management Practices for Case Investigation and Contact Tracing Leads
What Construction Workers Need to Know about COVID-19
What Construction Workers Need to Know about COVID-19
Potential drug treatment targets for alcohol-related liver disease
A team of researchers has uncovered key molecular step stones in ALD that may provide targets for drug therapy development.
Landmark recommendations on development of artificial intelligence and the future of global health
A landmark review of the role of artificial intelligence (AI) in the future of global health calls on the global health community to establish guidelines for development and deployment of new technologies and to develop a human-centered research agenda to facilitate equitable and ethical use of AI.
Cooperation can be contagious particularly when people see the benefit for others
Seeing someone do something good for someone else motivates witnesses to perform their own helpful acts, an insight that could help drive cooperative behavior in communities navigating through the health crisis.
Field courses boost student success, support STEM diversity efforts
The challenge of diversifying STEM fields may get a boost from the results of a new study that show field courses help build self-confidence among students -- especially those from underrepresented groups.
Scientists eliminate drug side effects by manipulating molecular chirality
Scientists have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.
вторник, 19 мая 2020 г.
Performing Facility-wide SARS-CoV-2 Testing in Nursing Homes
Performing Facility-wide SARS-CoV-2 Testing in Nursing Homes
Subcellular chatter regulates longevity
As people get older, they often feel less energetic, mobile or active. This may be due in part to a decline in mitochondria, the tiny powerhouses inside of our cells, which provide energy and regulate metabolism. In fact, mitochondria decline with age not only in humans, but in many species. Why they do so is not well understood. Scientists set out to understand how mitochondrial function is diminished with age and to find factors that prevent this process. They found that communication between mitochondria and other parts of the cell plays a key role.
Comedy club performances provide insights on how robots, humans connect via humor
A robot comic is more funny when it has good timing.
How to improve the pneumococcus vaccine
Pneumococcus kills 1 million children annually according to the World Health Organization. The key to the pathogen's virulence is its thick sugar capsule, which is also the active ingredient in vaccines. Different strains have different capsules. Researchers just identified a new capsule for the pneumococcus -- the 100th to be found after more than a century of research on the pathogen.
Dairy-rich diet linked to lower risks of diabetes and high blood pressure
Eating at least two daily servings of dairy is linked to lower risks of diabetes and high blood pressure, as well as the cluster of factors that heighten cardiovascular disease risk (metabolic syndrome), finds a large international study.
Location, location, location: The cell membrane facilitates RAS protein interactions
Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS. Now, scientists have uncovered details into how normal RAS interacts with mutated RAS and other proteins in living cells for the first time. The findings could aid in the development of better RAS-targeted cancer therapeutics.
Cavity-causing bacteria assemble an army of protective microbes on human teeth
It's not just the presence of bacteria that can lead to disease; their spatial arrangement also matters. When scientists examined the bacteria that causes tooth decay, they found it 'shields' itself under blankets of sugars and other bacteria in a crown-like arrangement, helping it evade antimicrobials and concentrate its tooth-damaging acids.
How experiencing traumatic stress leads to aggression
Traumatic stress can cause aggression by strengthening two brain pathways involved in emotion, according to new research. Targeting those pathways via deep brain stimulation may stymie aggression associated with post-traumatic stress disorder.
The brain's facial recognition area doesn't differentiate outgroup members
A quirk in how the brain processes faces makes it harder to tell members of a racial outgroup apart, according to new research.
Communities, Schools, Workplaces, and Events
Preventing COVID-19 spread in schools, workplaces, and communities.
Early visual experience drives precise alignment of cortical networks for binocular vision
Researchers identify three distinct cortical representations that develop independent of visual experience but undergo experience-dependent reshaping, an essential part of cortical network alignment and maturation.
Considerations for Youth and Summer Camps
CDC offers considerations for ways in which camp administrators can help protect campers, staff, and communities, and slow the spread of COVID-19.
Protein shapes matter in Alzheimer's research
Even a small change may cause long-term consequences. For amyloid beta peptides, a major hallmark of Alzheimer's disease, a common chemical modification at a particular location on the molecule has a butterfly effect that leads to protein misfolding, aggregation and cellular toxicity.
Observing the freely behaving brain in action
Scientists working at Caesar have developed a small head-mounted microscope that allows access to the inner workings of the brain. The new system enables measurement of activity from neuronal populations located in the deep cortical layer with single-cell resolution, in an animal that is freely behaving.
Considerations for Schools
CDC offers considerations for ways in which schools can help protect students, teachers, administrators, and staff and slow the spread of COVID-19.
Maintaining heart health may protect against cognitive decline
People with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers of Alzheimer's disease, suggesting that monitoring and controlling for heart disease may be key to maintaining and improving cognitive health later in life.
Found: Brain structure that controls our behavior
Solving problems, planning one's own actions, controlling emotions -- these executive functions are fundamental processes for controlling our behavior. Despite numerous indications, there has not yet been any clear evidence to support which brain areas process these abilities. A study has now succeeded in identifying the crucial region -- with the help of a unique patient and the not-so-rare dys-executive syndrome.
Artificial pieces of brain use light to communicate with real neurons
Researchers have created a way for artificial neuronal networks to communicate with biological neuronal networks. The new system converts artificial electrical spiking signals to a visual pattern than is then used to entrain the real neurons via optogenetic stimulation of the network. This advance will be important for future neuroprosthetic devices that replace damages neurons with artificial neuronal circuitry.
COVID-19: Study reports 'staggering' death rate in U.S. among those infected who show symptoms
A new study finds the national U.S. rate of death among people infected with the novel coronavirus -- SARS-CoV-2 -- that causes COVID-19 and who show symptoms is 1.3 percent, the study found. The comparable rate of death for the seasonal flu is 0.1 percent.
Gestures heard as well as seen
Gesturing with the hands while speaking is a common human behavior, but no one knows why we do it. Now, a group of researchers reports that gesturing adds emphasis to speech -- but not in the way researchers had thought.
Technology makes brain and other tissues elastic and lasting for easier imaging
By making brain and other tissues reversibly stretchable or compressible, a new technology called 'ELAST' allows labeling probes to infuse more quickly.
Climate change threatens progress in cancer control
Climate change threatens prospects for further progress in cancer prevention and control, increasing exposure to cancer risk factors and impacting access to cancer care, according to a new commentary.
Protect Yourself and Others from COVID-19 When Visiting Parks and Recreational Facilities
Protect Yourself and Others from COVID-19 When Visiting Parks and Recreational Facilities
O que trabalhadores e empregadores podem fazer para gerir a fadiga no local de trabalho durante a COVID-19
O que trabalhadores e empregadores podem fazer para gerir a fadiga no local de trabalho durante a COVID-19
Was Arbeitnehmer und Arbeitgeber tun können, um mit der Müdigkeit am Arbeitsplatz während COVID-19 umzugehen
Was Arbeitnehmer und Arbeitgeber tun können, um mit der Müdigkeit am Arbeitsplatz während COVID-19 umzugehen
What Workers and Employers Can Do to Manage Workplace Fatigue during COVID-19
What Workers and Employers Can Do to Manage Workplace Fatigue during COVID-19
What Long-haul Truck Drivers Need to Know about COVID-19
What Long-haul Truck Drivers Need to Know about COVID-19
понедельник, 18 мая 2020 г.
HHS Delivers Funding to Expand Testing Capacity for States, Territories, Tribes
The Department of Health and Human Services (HHS) is delivering $11 billion in new funding to support testing for COVID-19. The Centers for Disease Control and Prevention (CDC) will provide $10.25 billion to states, territories, and local jurisdictions through CDC's existing Epidemiology and Laboratory Capacity for Prevention and Control of Emerging Infectious Diseases (ELC) cooperative agreement.
Interim Infection Prevention and Control Recommendations for Patients with Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) in Healthcare Settings
Guidance for healthcare professionals who have the potential for direct or indirect exposure to patients or infectious materials.
Aluminum may affect lead levels in drinking water
Until recently, researchers have not inspected the interplay between three common chemicals found in drinking water. Research has now found they all affect each other and a closer look is needed.
Scientists inject proteins into eukaryontic cells
When bacteria such as Salmonella or Yersinia cause fever, diarrhea or abdominal pain, tiny "injection needles" are at work: their type 3 secretion system, or T3SS for short, shoots bacterial virulence proteins directly into the eukaryotic host cells. Researchers have thought of using bacterial injection devices to introduce proteins into eukaryotic cells. A research team has now succeeded in controlling the injection system optogenetically, i.e. with light. In the future this will enable to use the system in biotechnological or medical applications.
Brain-to-gut connections traced
Using rabies virus injected into the stomach of rats, researchers trace the nerves back to the brain and find distinct 'fight or flight' and 'rest and digest' circuits. These results explain how mental states can affect the gut, and present new ways to treat gastrointestinal problems.
Releasing molecular 'brake' kick-starts immune cell function
The immune system's ability to marshal specialized cells to fight off infection relies in part on tiny molecules called microRNAs, which act as a release for the 'brakes' that keep cells dormant until needed, according to a new study.
A new tool to map the flow of info within living cells
Researchers created a way to study the intricacies of intercellular signaling -- when, where, and how tiny parts of cells communicate -- to make cells move. The work provides insights into the movement mechanisms in healthy cells and what these change might look like disease states, such as cancer metastasis.
Global study confirms influential theory behind loss aversion
A new global study offers a powerful confirmation of one of the most influential frameworks in all of behavioral sciences and behavioral economics: prospect theory, which when introduced in 1979 led to a sea change in understanding the irrational and paradoxical ways individuals make decisions and interpret risk. The new study in 19 countries and 13 languages replicates the original study that provided the empirical basis for prospect theory.
Chinese to rise as a global language
With the continuing rise of China as a global economic and trading power, there is no barrier to prevent Chinese from becoming a global language like English, according to new research.
Scientists find brain center that 'profoundly' shuts down pain
A research team has found a small area of the brain in mice that can profoundly control the animals' sense of pain. Somewhat unexpectedly, this brain center turns pain off, not on. It's located in an area where few people would have thought to look for an anti-pain center, the amygdala, which is often considered the home of negative emotions and responses, like the fight or flight response and general anxiety.
Engineers develop low-cost, high-accuracy GPS-like system for flexible medical robots
Roboticists have developed an affordable, easy to use system to track the location of flexible surgical robots inside the human body. The system performs as well as current state of the art methods, but is much less expensive. Many current methods also require exposure to radiation, while this system does not.
Identify the Primary Components of COVID-19 Contact Tracing
Identify the Primary Components of COVID-19 Contact Tracing
Identify Jurisdiction-Specific Contact Tracing Tools and Protocols
Identify Jurisdiction-Specific Contact Tracing Tools and Protocols
Identify Jurisdiction-Specific Case Investigation Tools
Identify Jurisdiction-Specific Case Investigation Tools
Analyze Contact Tracing Encounters for Continuous Quality Improvement
Analyze Contact Tracing Encounters for Continuous Quality Improvement
Apply COVID-19 Contact Tracing Protocol to Realistic Scenarios
Apply COVID-19 Contact Tracing Protocol to Realistic Scenarios
Aging neurons accumulate DNA damage
Neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. HDAC1 is often diminished in both Alzheimer's patients and in normally aging adults, and the study suggests restoring it could have positive benefits for both groups.
Study on body posture: Can powerful poses improve self-confidence in children?
A dominant body posture may help children to feel more confident in school. These are the findings of a new study by psychologists. The study provides initial evidence that simple poses can help students feel better at school.
воскресенье, 17 мая 2020 г.
CDC Activities and Initiatives Supporting the COVID-19 Response and the President's Plan for Opening America Up Again
This document briefly summarizes CDC's initiatives, activities, and tools in support of the Whole-of-Government response to COVID-19.
Support for States, Tribes, Localities and Territories
Support for States, Tribes, Localities and Territories
суббота, 16 мая 2020 г.
Recommendation Regarding the Use of Cloth Face Coverings, Especially in Areas of Significant Community-Based Transmission
Recommendation Regarding the Use of Cloth Face Coverings, Especially in Areas of Significant Community-Based Transmission
Foolproof new test to track the fats we eat
A team of researchers has developed a reliable and accurate blood test to track individual fat intake, a tool that could guide public health policy on healthy eating.
Binge drinkers beware, Drunkorexia is calling
Mojito, appletini or a simple glass of fizz -- they may take the edge off a busy day, but if you find yourself bingeing on more than a few, you could be putting your physical and mental health at risk according new research.
New bone-graft biomaterial gives patients a nicer smile and less pain
A new recipe for a bone-graft biomaterial that is supercooled before application should make it easier to meet dental patients' expectation of a good-looking smile while eliminating the pain associated with harvesting bone from elsewhere in their body.
Retinal texture could provide early biomarker of Alzheimer's disease
Biomedical engineers have devised a new imaging device capable of measuring both the thickness and texture of the various layers of the retina. The advance could be used to detect a biomarker of Alzheimer's disease, potentially offering a widespread early warning system for the disease.
Designing vaccines from artificial proteins
Scientists have developed a new computational approach to create artificial proteins, which showed promising results in vivo as functional vaccines. This approach opens the possibility to engineer safer and more effective vaccines.
'Metabolic signature' can determine adherence to Mediterranean diet, help predict CVD risk
A newly identified 'metabolic signature' can evaluate an individual's adherence and metabolic response to the Mediterranean diet and help predict future risk of developing cardiovascular disease.
New research into stem cell mutations could improve regenerative medicine
Research has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring.
Mouse and human eye movements share important similarity
Scientists have used a lightweight eye-tracking system composed of miniature video cameras and motion sensors to record head and eye movements in mice without restricting movement or behavior. Measurements were made while the animals performed naturalistic visual behaviors including social interactions with other mice and visual object tracking.
New ways to nudge the brain
For army scientists, the goal of neuroscience research is pursuing the inner workings of the human brain to advance scientific understanding and improve soldier performance.
Decoding the massively complex gut microbiome
For something that has evolved with us over millions of years, and remains part of our physiology over our entire lives, our gut microbiome, oddly, remains somewhat of a mystery. Comprised of trillions of microbes of at least a thousand different species, this community of bacteria, viruses, protozoa and fungi in our gastrointestinal tracts is unique to each individual and has been found to be intimately connected to various fundamental aspects of our fitness, from our immunity to our metabolism and mental health.
Repurposed drug helps obese mice lose weight, improve metabolic function
An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized body weight and reversed metabolic damage in obese middle-aged mice of both sexes.
One-two punch may help fight against Salmonella
Researchers found that dephostatin does not kill Salmonella or stop it from growing. Instead, dephostatin prevents Salmonella from causing infection in two ways: it blocks its ability to resist being killed by immune cells and it enhances its sensitivity to colistin.
Vitamin B3 revitalizes energy metabolism in muscle disease
Scientists have reported that vitamin B3, niacin, has therapeutic effect in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments.
Checklist for Homeless Service Providers During Community Re-opening
Checklist for Homeless Service Providers During Community Re-opening
пятница, 15 мая 2020 г.
COVID-19 Contact Tracing Training Guidance and Resources
COVID-19 Contact Tracing Training Guidance and Resources
COVID-19 infection control, radiographer protection in CT exam areas
Radiologists from Shanghai discuss modifying exam process and disinfecting exam room, while outlining personal protection measures during the coronavirus disease outbreak.
Blood clotting abnormalities reveal COVID-19 patients at risk for thrombotic events
A new article highlights early research on blood clotting evaluation work that may help identify and treat dangerous complications of the infection.
Heart attacks, heart failure, stroke: COVID-19's dangerous cardiovascular complications
A new guide from emergency medicine doctors details the potentially deadly cardiovascular complications COVID-19 can cause.
Antiviral drug can speed up recovery of COVID-19 patients, study shows
Research shows for the first time that interferon-alpha2b improves virus clearance and decreases levels of inflammatory markers in COVID-19 patients.
SARS lessons for COVID-19 vaccine design
Important lessons learned from the Severe Acute Respiratory Syndrome (SARS) outbreak of 2002-2003 could inform and guide vaccine design for COVID-19, according to a new article.
Communities, Schools, Workplaces, and Events
Preventing COVID-19 spread in schools, workplaces, and communities.
The dreaming brain tunes out the outside world
Scientists have shown that the brain suppresses information from the outside world, such as the sound of a conversation, during the sleep phase linked to dreaming. This ability could be one of the protective mechanisms of dreams.
Communication Toolkit for Transportation Partners to Inform Road Travelers
Communication Toolkit for Transportation Partners to Inform Road Travelers
Factors to Consider When Planning to Purchase Respirators from Another Country
Factors to Consider When Planning to Purchase Respirators from Another Country
Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)
Learn about hospital surveillance (rates) and how that information helps find who is most at risk for severe illness and death, including important demographic information
Standard Operating Procedure (SOP) for Triage of Suspected COIVD-19 Patients in non-US Healthcare Settings
Standard Operating Procedure (SOP) for Triage of Suspected COIVD-19 Patients in non-US Healthcare Settings
Malaria parasite ticks to its own internal clock
Researchers have long known that all of the millions of malaria parasites within an infected person's body move through their cell cycle at the same time. They multiply in sync inside red blood cells, then burst out in unison every few days. But how the parasites keep time was unclear. Now, a study finds that malaria has its own internal clock that causes thousands of genes to ramp up and down at regular intervals.
четверг, 14 мая 2020 г.
If You Are Immunocompromised, Protect Yourself From COVID-19
If You Are Immunocompromised, Protect Yourself From COVID-19
Misleading information in 1 in 4 most viewed YouTube COVID-19 videos in English, study finds
More than one in four of the most viewed COVID-19 videos on YouTube in spoken English contains misleading or inaccurate information, reveals the first study of its kind.
Infecting the mind: Burnout in health care workers during COVID-19
Doctors and nurses across the country are experiencing occupational burnout and fatigue from the increased stress caused by the COVID-19 pandemic. A team of researchers and medical professionals are working together to fight two afflictions: COVID-19 and the mental strain experienced by medical professionals.
In victory over polio, hope for the battle against COVID-19
Medicine's great triumph over polio holds out hope we can do the same for COVID-19, two researchers say.
Surplus antioxidants are pathogenic for hearts and skeletal muscle
Oxidative stress can be pathological. Now researchers report that the other end of the redox spectrum, reductive stress, is also pathological. Reductive stress causes pathological heart enlargement and diastolic dysfunction in a mouse model.
Discovery of malaria parasite's clock could pave way to new treatments
The parasite that causes malaria has its own internal clock, explaining the disease's rhythmic fevers and opening new pathways for therapeutics.
Dynamic stimulation of the visual cortex allows blind and sighted people to 'see' shapes
A team of investigators has described an approach in which implanted electrodes are stimulated in a dynamic sequence, essentially 'tracing' shapes on the surface of the visual cortex that participants were able to 'see.'
The exposome: When our environment drives health and disease
The exposome is the sum of all the environmental drivers of health and diseases: a combination of external factors such as chemicals contained in the air, water or food, and of internal components produced by our organism in response to various stress factors. This very complex set of elements is continually evolving, and to map it fully is a challenging undertaking.
Cases & Latest Updates
CDC is aggressively responding to the global outbreak of COVID-19 and preparing for the potential of community spread in the United States.
New guidance related to COVID-19 and stroke care
Researchers have published more than 40 new recommendations for evaluating and treating stroke patients based on international research examining the link between stroke and novel coronavirus (COVID-19).
Unlocking the gate to the millisecond CT
Researchers have developed a new multi-beam method for conducting CT scans that improve image quality whilst drastically cutting the required time to one millisecond.
Can COVID-19 spread through fecal matter?
Early studies show evidence of COVID-19 genetic material in fecal matter, but more work is needed to determine if the virus can be spread through stool, according to a new review paper.
Study confirms cats can become infected with and may transmit COVID-19 to other cats
Scientists report that in the laboratory, cats can readily become infected with SARS-CoV-2, the virus that causes COVID-19, and may be able to pass the virus to other cats.
Coffee linked to lower body fat in women
Women who drink two or three cups of coffee a day have been found to have lower total body and abdominal fat than those who drink less, according to a new study.
Arthritis drug may improve respiratory function in some patients with severe COVID-19
A small study in Greece found that the clinically approved anti-inflammatory drug anakinra, used to treat rheumatoid arthritis, improved respiratory function in patients with severe coronavirus disease 2019 (COVID-19).
'Cell pores' discovery gives hope to millions of brain and spinal cord injury patients
Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year.
People Who are at Higher Risk
COVID-19 is a new disease and there is limited information regarding risk factors for severe disease. Based on currently available information and clinical expertise, older adults and people of any age who have serious underlying medical conditions might be at higher risk for severe illness from COVID-19.
COVID-19 Forecasts for the United States
CDC works with partners to bring together weekly forecasts for COVID-19 deaths in one place. These forecasts have been developed independently and shared publicly. It is important to bring these forecasts together to help understand how they compare with each other and how much uncertainty there is about what may happen in the upcoming four weeks.
среда, 13 мая 2020 г.
Signs of fetal alcohol syndrome detected in womb
New images reveal the earliest impairments to nonhuman primate fetal brain development due to alcohol ingested by the mother, in a study involving rhesus macaques. Magnetic resonance imaging showed impairments to brain growth during the third trimester of pregnancy, even though the fetus was exposed to alcohol only during the first trimester.
Low proportion of individuals with autism receive recommended genetic tests, study finds
A new study found that only 3 percent of individuals diagnosed with autism spectrum disorder reported having fully received clinical genetic tests recommended by medical professional societies.
Is video game addiction real?
A recent six-year study, the longest study ever done on video game addiction, found that about 90% of gamers do not play in a way that is harmful or causes negative long-term consequences. A significant minority, though, can become truly addicted to video games and as a result can suffer mentally, socially and behaviorally.
Aerobics may be a smart workout for your brain at any age
It's never too late to lace up some sneakers and work up a sweat for brain health, according to a new study. The study suggests older adults, even couch potatoes, may perform better on certain thinking and memory tests after just six months of aerobic exercise.
Biomechanics: 'Off-road' mode enables mobile cells to move freely
Cancer cells and leukocytes are able to move through tissue and organs quickly. However, it is not fully understood how these mobile cells manage to travel and survive far away from their place of origin. Scientists have now revealed a general biomechanical principle of cell migration that allows cells to move freely, especially in rough terrain.
Not all psychopaths are violent; a new study may explain why some are 'successful' instead
Psychopathy is widely recognized as a risk factor for violent behavior, but many psychopathic individuals refrain from antisocial or criminal acts. Understanding what leads these psychopaths to be 'successful' has been a mystery. A new study conducted by researchers at Virginia Commonwealth University sheds light on the mechanisms underlying the formation of this 'successful' phenotype.
Interim Operational Considerations for Public Health Management of Healthcare Workers Exposed to or Infected with COVID-19: non-US Healthcare Settings
Interim Operational Considerations for Public Health Management of Healthcare Workers Exposed to or Infected with COVID-19: non-US Healthcare Settings
Clean & Disinfect
Guidance on the cleaning and disinfection of households where persons under investigation (PUI) or those with confirmed COVID-19 reside or may be in self-isolation.
Durable, washable textile coating can repel viruses
Researchers have created a textile coating that can not only repel liquids like blood and saliva but can also prevent viruses from adhering to the surface.
Protein that helps cancer cells to survive
In a new study, researchers have discovered two important functions of a protein called RTEL1 during cell division. The researchers hope that the new knowledge will help to find new cancer treatments.
Celiac disease linked to common chemical pollutants
Elevated blood levels of toxic chemicals found in pesticides, nonstick cookware, and fire retardants have been tied to an increased risk for celiac disease in young people, new research shows.
Interim Guidance for Responding to Coronavirus Disease 2019 (COVID-19) among People Experiencing Unsheltered Homelessness
Guidance intended to provide key actions that local and state health departments, homelessness service systems, housing authorities, emergency planners, healthcare facilities, and homeless outreach services can take to protect people experiencing homelessness from the spread of COVID-19.
Meat and Poultry Processing Workers and Employers
Guidance for Meat and Poultry Processing Workers and Employers
Missing component of innate immune signaling identified
Scientists have identified a new key element of the multi-component machinery responsible for sorting out the nature and severity of the pathogen challenge. The new protein, named TASL, is indispensable for the signaling of so-called Toll-like receptors (TLR) in the endosomes leading to activation of the gene-activator IRF5 in certain immune cells.
Most powerful gene variant for height known to date
Newly discovered gene variant in Peruvian populations is powerfully linked with height. Five percent of Peruvians carry the variant, which originates exclusively from Native American populations. The variant occurs on a gene that, when mutated, causes Marfan syndrome, a condition marked by connective tissue abnormalities, including serious cardiovascular problems. The newly discovered variant is not associated with disease and may confer adaptive evolutionary advantage to populations that carry it.
Special Considerations for Patients on Home Dialysis
Special Considerations for Patients on Home Dialysis
Brain signal measurement using printed tattoo electrodes
Researchers have developed ultra-light tattoo electrodes that are hardly noticeable on the skin and make long-term measurements of brain activity cheaper and easier.
Team shares blueprint for adapting academic research center to SARS-CoV-2 testing lab
In a new article, researchers describe how they adapted their lab to test patient samples for SARS-CoV-2, and they provide a blueprint for other labs that want to do the same thing.
Scientists show MRI predicts the efficacy of a stem cell therapy for brain injury
Scientists have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury -- a first-ever 'biomarker' for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve efficacy.
Frequently Asked Questions and Answers: Coronavirus Disease 2019 (COVID-19) and Pregnancy
We do not have information from published scientific reports about the susceptibility of pregnant women to COVID-19.
Interim Infection Prevention and Control Guidance for Veterinary Clinics During the COVID-19 Response
Interim Infection Prevention and Control Guidance for Veterinary Clinics During the COVID-19 Response
Why visual perception is a decision -making process
A popular theory in neuroscience called predictive coding proposes that the brain produces all the time expectations that are compared with incoming information. Errors arising from differences between actual input and prediction are then iteratively minimized along a hierarchical processing scheme. It is assumed that such stepwise iteration leads to updating of brain predictions so that internal prediction errors are finally explained away.
New weapon identified in arsenal against disease
New research describes the structure and composition of supramolecular attack particles (SMAPs) and their role in killing targeted cells. Identified as having a core of cytotoxic proteins surrounded by a glycoprotein shell the SMAPs are released by killer T cells and can be left in the environment like a landmine to await and destroy infected and cancerous cells.
вторник, 12 мая 2020 г.
Framework for Healthcare Systems Providing Non-COVID-19 Clinical Care During the COVID-19 Pandemic
Framework for Healthcare Systems Providing Non-COVID-19 Clinical Care During the COVID-19 Pandemic
Considerations for Memory Care Units in Long-term Care Facilities
Considerations for Memory Care Units in Long-term Care Facilities
New tool helps distinguish the cause of blood clots
A new tool using cutting-edge technology is able to distinguish different types of blood clots based on what caused them, according to a new study.
Too little sleep can mean more asthma attacks in adults
A new article reveals that too little sleep, and occasionally too much sleep, can negatively impact adults with asthma.
Resources for Large Community Events & Mass Gatherings
Resources for large community events and mass gatherings
What we can't see can help us find things
Anyone who's ever tried to find something in a hurry knows how helpful it is to think about the lost item's color, size and shape. But surprisingly, traits of an object that you can't see also come into play during a search, researchers found.
Communication Toolkit for Airlines to inform Travelers and Crew
Communication Toolkit for Airlines to inform Travelers and Crew
Information for Healthcare Professionals
Resources for Healthcare Professionals Caring for COVID-19 Patients
Public Health Recommendations for People in U.S. Communities Exposed to a Person with Known or Suspected COVID-19, other than Health Workers or other Critical Infrastructure Workers
Public Health Recommendations for People in U.S. Communities Exposed to a Person with Known or Suspected COVID-19, other than Health Workers or other Critical Infrastructure Workers
Coronavirus disease 2019 (COVID-19) Checklist: Older Persons
Coronavirus disease 2019 (COVID-19) Checklist: Older Persons
Protect your home
You can plan and make decisions now that will protect you and your family during a COVID-19 outbreak. Learn what you can do to prepare your home and family.
Presence of spouse alters how parents' brains react to children stimuli
A study has revealed how the physical presence of spouses who are co-parenting can alter each other's brain activity.
World-first saliva test detects hidden throat cancer
A series of saliva HPV tests detected an asymptomatic throat cancer during a trial of a new saliva diagnostic. Further validation studies are needed to confirm this finding. It is a world-first discovery, previously there was no screening test for HPV-DNA oropharyngeal cancers. The patient had surgery in which a 2 mm cancer was removed and has had no recurrence of HPV-DNA in his saliva.
Link between blood vessel inflammation, malfunctioning cellular powerhouses
Scientists have uncovered a novel mechanism by which abnormalities in mitochondrial fission in endothelial cells contribute to inflammation and oxidative stress in the cardiovascular system. They further show how the fission-fusion balance can be stabilized to lower inflammation using salicylate, the main active ingredient in everyday pain-relieving drugs like aspirin.
понедельник, 11 мая 2020 г.
Infection Prevention and Control Assessment Tool for Nursing Homes Preparing for COVID-19
Infection Prevention and Control Assessment Tool for Nursing Homes Preparing for COVID-19
Multitasking in the workplace can lead to negative emotions
From writing papers to answering emails, it's common for office workers to juggle multiple tasks at once. But those constant interruptions can actually create sadness and fear and eventually, a tense working environment, according to a new study aimed at understanding what shapes the emotional culture of a workplace.
Street smarts required in heat mitigation
Researchers investigated how solar reflective coatings on select Los Angeles city streets affected radiant heat and, in turn, pedestrians' comfort on a typical summer day. The idea is, if you coat a street with a lighter color than traditional pavement black, it will actually lower the surrounding temperatures. But researchers wanted to measure what effect reflective coating had on pedestrians.
Polymer composite could serve as lighter, non-toxic radiation shielding
A new study suggests that a polymer compound embedded with bismuth trioxide particles holds tremendous potential for replacing conventional radiation shielding materials, such as lead.
Researchers ID target for colorectal cancer immunotherapy
Researchers have identified a target for colorectal cancer immunotherapy.
Single-cell RNA seq developed to accurately quantify cell-specific drug effects in pancreatic islets
Researchers have developed a method to accurately assess the effect of specific drugs in isolated pancreatic tissue by using a refined single-cell RNA sequencing method. Their study describes their technique to overcome the problem of contaminating RNA molecules in single-cell transcriptomics, allowing for accurate results of dynamic drug responses in pancreatic cells.
Antihistamines may help patients with malignant melanoma
Can a very common allergy medicine improve survival among patients suffering from the serious skin cancer, malignant melanoma? A new study indicates that this may be the case.
New HIV vaccine strategy strengthens, lengthens immunity in primates
Investigators have shown that a new type of vaccination can substantially enhance and sustain protection from HIV.
How is COVID-19 affecting the global economic order?
COVID-19 has triggered a global financial crisis and is forcing states to develop rescue packages on a scale not seen before. The crisis has called into question the US dollar's hegemony and could redefine the global monetary system. Researchers have developed four scenarios that show how political decisions will shape the post-Corona world.
Even animals benefit from social distance to prevent disease, research shows
Researchers have uncovered evidence about the importance of maintaining physical distance to minimize the spread of microbes among individuals. Monkeys were observed in the wild to understand what role genetics, diet, social groupings and distance in a social network play when it comes to the microbes found inside an animal's gut.
Men's blood contains greater concentrations of enzyme that helps COVID-19 infect cells
Evidence from a large study of several thousand patients in 11 European countries shows that men have higher concentrations of angiotensin-converting enzyme 2 (ACE2) in their blood than women. Since ACE2 enables the coronavirus to infect healthy cells, this may help to explain why men are more vulnerable to COVID-19 than women.
Pediatric coronavirus disease (COVID-19) X-ray, CT in review of new lung disorders
Although the clinical symptoms of SARS, H1N1, MERS, EVALI, and COVID-19 may be nonspecific, some characteristic imaging findings are emerging, according to a new article. Careful evaluation of the distribution, lung zone preference, and symmetry of the abnormalities with an eye for a few unique differentiating imaging features can allow radiologists to offer a narrower differential diagnosis in pediatric patients, leading to optimal patient care.
New AI diagnostic can predict COVID-19 without testing
Researchers have developed an artificial intelligence diagnostic that can predict whether someone is likely to have COVID-19 based on their symptoms.
Artificial synapses on design
Memristive devices behave similarly to neurons in the brain. Researchers have now discovered how to systematically control the functional behaviour of these elements. The smallest differences in material composition are found crucial: differences so small that until now experts had failed to notice them.
Factors to Consider When Planning to Purchase Respirators from Another Country
Factors to Consider When Planning to Purchase Respirators from Another Country
COVID-19 Infection Prevention and Control in Healthcare Settings: Questions and Answers
Information supports healthcare personnel who may care for patients who are confirmed with or under investigation for COVID-19.
Emotional well-being while home gardening similar to other popular activities, study finds
Researchers found that gardening at home had a similar effect on emotional well-being (or happiness) as biking, walking or dining out. The benefits were similar across racial boundaries and between urban and suburban residents, and it was the only activity out of the 15 studied for which women and people with low incomes reported the highest emotional well-being. The results suggest that household gardens could be key to providing food security in urban areas and making cities more sustainable and livable.
COVID-19 lockdowns significantly impacting global air quality
Levels of two major air pollutants have been drastically reduced since lockdowns began in response to the COVID-19 pandemic, but a secondary pollutant -- ground-level ozone -- has increased in China, according to new research.
CDC's role in helping cruise ship travelers during the COVID-19 pandemic
CDC's role in helping cruise ship travelers during the COVID-19 pandemic
Interim Laboratory Biosafety Guidelines for Handling and Processing Specimens Associated with Coronavirus Disease 2019 (COVID-19)
Until more information becomes available, precautions should be taken in handling specimens that are suspected or confirmed for SARS-CoV-2.
A close relative of SARS-CoV-2 found in bats offers more evidence it evolved naturally
Researchers describe a recently identified bat coronavirus that contains insertions of amino acids at the junction of the S1 and S2 subunits of the virus's spike protein in a manner similar to SAR-CoV-2. While it's not a direct evolutionary precursor of SARS-CoV-2, this new virus, RmYN02, suggests that these types of seemingly unusual insertion events can occur naturally in coronavirus evolution.
Are our brains hard-wired for longing?
A new brain imaging study of prairie voles -- which are among only about 5% of mammalian species besides humans who are monogamous -- found that when it comes to forming bonds, longing may be as important as being together. The study also sheds light on why it's so hard to social distance, and could lead to new therapies for conditions like autism and depression.
Children face risk for severe complications and death from COVID-19
Children, teens and young adults are at greater risk for severe complications from COVID-19 than previously thought and those with underlying health conditions are at even greater risk, according to a new study.
Coordinated strategy to accelerate COVID-19 vaccine candidates is key, experts say
A harmonized and collaborative approach to the clinical testing, scale-up and distribution of candidate vaccines to prevent COVID-19 is essential, scientific leaders say in a new article.
Imaging reveals bowel abnormalities in patients with COVID-19
Patients with COVID-19 can have bowel abnormalities, including ischemia, according to a new study.
COPD and smoking associated with higher COVID-19 mortality
Current smokers and people with chronic obstructive pulmonary disease (COPD) have an increased risk of severe complications and higher mortality with COVID-19 infection, according to a new study.
Sex, genes and vulnerability
Study offers molecular explanation for long-standing observation that certain diseases occur more often or more severely in different sexes. Complement component 4 (C4) genes protect against the autoimmune disorders lupus and Sjögren's syndrome while raising risk of severe schizophrenia.
Caring for someone at home
Most people who get sick with COVID-19 will have only mild illness and should recover at home. Care at home can help stop the spread of COVID-19 and help protect people who are at risk for getting seriously ill from COVID-19.
Healthy eating behaviors in childhood may reduce the risk of adult obesity and heart disease
Encouraging children to make their own decisions about food, within a structured environment focused on healthy food choices, has been linked to better childhood nutrition and healthier lifelong eating behaviors. Parents and caregivers can play a significant role in creating an environment that helps children develop healthier eating behaviors early in life, which can reduce the risk for overweight, obesity and cardiovascular disease as adults.
воскресенье, 10 мая 2020 г.
суббота, 9 мая 2020 г.
Support for States, Tribes, Localities and Territories
Support for States, Tribes, Localities and Territories
Information for Laboratories
This page includes interim guidance and resources for laboratory professionals working with specimens from persons under investigation (PUI) for coronavirus disease 2019 (COVID-19).
SPHERES
With extensive participation from US clinical and public health laboratories, academic institutions, and the private sector, the SPHERES consortium aims to generate information about the virus that will strengthen COVID-19 mitigation strategies.
Frequently Asked Questions on COVID-19 Testing at Laboratories
Frequently Asked Questions on COVID-19 Testing at Laboratories
Frequently Asked Questions and Answers: Coronavirus Disease-2019 (COVID-19) and Children
Most confirmed cases of COVID-19 reported from China have occurred in adults.
пятница, 8 мая 2020 г.
Considerations for Public Pools, Hot Tubs, and Water Playgrounds During COVID-19
Considerations for Public Pools, Hot Tubs, and Water Playgrounds During COVID-19
COVID-19 Contact Tracing Training Guidance and Resources
COVID-19 Contact Tracing Training Guidance and Resources
Individualized mosaics of microbial strains transfer from the maternal to the infant gut
Researchers have used a microbiome 'fingerprint' method to report that an individualized mosaic of microbial strains is transmitted to the infant gut microbiome from a mother giving birth through vaginal delivery. They detailed this transmission by analyzing existing metagenomic databases of fecal samples from mother-infant pairs, as well as analyzing mouse dam and pup transmission in a germ-free, or gnotobiotic, mouse model, where the dams were inoculated with human fecal microbes.
Newly discovered cell type plays crucial role in immune response to respiratory infections
With a discovery that could rewrite the immunology textbooks, an international group of scientists have identified a new type of antigen-presenting immune cell.
Promising study offers hope for Menkes disease patients
A research team has good news for patients with copper-deficiency disorders, especially young children diagnosed with Menkes disease.
To err is human, to learn, divine
New research describes a new model for how the brain interprets patterns in complex networks. They found that the ability to detect patterns stems in part from the brain's desire to represent things in the simplest way possible and that the brain is constantly weighing the pressures of complexity and simplicity when making decisions.
Plasma medicine research highlights antibacterial effects and potential uses
As interest in the application of plasma medicine -- the use of low-temperature plasma (LTP) created by an electrical discharge to address medical problems -- continues to grow, so does the need for research advancements proving its capabilities and potential impacts on the health care industry. Across the world, many research groups are investigating plasma medicine for applications including cancer treatment and the accelerated healing of chronic wounds, among others.
How does the brain link events to form a memory? Study reveals unexpected mental processes
The brain has a powerful ability to remember and connect events separated in time. And now, in a new study in mice, scientists have shed light on how the brain can form such enduring links.
Cases & Latest Updates
CDC is aggressively responding to the global outbreak of COVID-19 and preparing for the potential of community spread in the United States.
More selective elimination of leukemia stem cells and blood stem cells
Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. Researchers have now shown how human healthy and cancerous hematopoietic stem cells can be more selectively eliminated using immunotherapy instead of chemotherapy in mice. The aim is to test the new immunotherapy in humans as soon as possible.
What Waste Collectors and Recyclers Need to Know about COVID-19
What Waste Collectors and Recyclers Need to Know about COVID-19
Canadian study finds temperature, latitude not associated with COVID-19 spread
A new study finds that temperature and latitude do not appear to be associated with the spread of coronavirus disease 2019 (COVID-19), but school closures and other public health measures are having a positive effect.
What Long-haul Truck Drivers Need to Know about COVID-19
What Long-haul Truck Drivers Need to Know about COVID-19
Newly discovered mechanism can explain increased risk of dementia
Millions of people around the world use acid suppressants called proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that how the long-term use of these drugs could increase the risk of developing dementia. Their results are published in the journal Alzheimer's & Dementia.
четверг, 7 мая 2020 г.
Clean & Disinfect
Guidance on the cleaning and disinfection of households where persons under investigation (PUI) or those with confirmed COVID-19 reside or may be in self-isolation.
Get Your Mass Gatherings or Large Community Events Ready
This interim guidance is intended for organizers and staff responsible for planning mass gatherings or large community events in the United States. A mass gathering is a planned or spontaneous event with a large number of people in attendance that could strain the planning and response resources of the community hosting the event, such as a concert, festival, conference, or sporting event.
Environmental Cleaning and Disinfection Recommendations
Environmental Cleaning and Disinfection Recommendations
Olanzapine may help control nausea, vomiting in patients with advanced cancer
Olanzapine, a generic drug used to treat nervous, emotional and mental conditions, also may help patients with advanced cancer successfully manage nausea and vomiting unrelated to chemotherapy.
Blood thinners may improve survival among hospitalized COVID-19 patients
Treating hospitalized COVID-19 patients with anticoagulants -- blood thinners that slow down clotting -- may improve their chances of survival, researchers report. The study could provide new insight on how to treat and manage coronavirus patients once they are admitted to the hospital.
Key mechanism of cytokine storm in Castleman disease
Researchers discover what is happening at the cellular level when Castleman patients experience a cytokine storm.
A role reversal for the function of certain circadian network neurons
A new study y reveals surprising findings about the function of circadian network neurons that undergo daily structural change. The research could lead to a better understanding of how to address circadian rhythm disruptions in humans and facilitate preventing a host of associated health problems, including increased risk for cancer and metabolic syndrome.
Accurate 3D imaging of sperm cells moving at top speed could improve IVF treatments
Researchers have developed a safe and accurate 3D imaging method to identify sperm cells moving at a high speed. The new method has the potential to significantly improve IVF treatments.
The feeling a limb doesn't belong is linked to lack of brain structure and connection
People with body integrity dysphoria (BID) often feel as though one of their healthy limbs isn't meant to be a part of their bodies. They may act as though the limb is missing or even seek its amputation 'to feel complete.' Now, researchers have found that these feelings that a limb doesn't belong are mirrored in the brains of people with this condition.
See a 3D mouse brain with single-cell resolution
A manually constructed 3D atlas offers a cellular-level view of the entire mouse brain. This reference brain, called the Allen Mouse Brain Common Coordinate Framework (CCFv3), is derived from serial two-photon tomography images of 1,675 mice.
Fighting autoimmunity and cancer: The nutritional key
Scientists have revealed a novel mechanism through which the immune system controls autoimmunity and cancer. In the special focus of the researchers were regulatory T cells -- a type of white blood cells that act as a brake on the immune system.
Lipid metabolism controls brain development
A lipid metabolism enzyme controls brain stem cell activity and lifelong brain development. If the enzyme does not work correctly, it causes learning and memory deficits in humans and mice, as researchers have discovered. Regulating stem cell activity via lipid metabolism could lead to new treatments for brain diseases.
Safely relaxing social distancing comes down to numbers
Your house number could be the key to the safe relaxation of COVID-19-related restrictions if governments follow a new exit strategy, which proposes the use of an 'odds-and-evens' approach to allowing people to head back to work and enjoy other activities after weeks of lockdown.
Vitamin D linked to low virus death rate, study finds
A new study has found an association between low average levels of vitamin D and high numbers of COVID-19 cases and mortality rates across 20 European countries.
Vitamin D levels appear to play role in COVID-19 mortality rates
Researchers analyzed patient data from 10 countries. The team found a correlation between low vitamin D levels and hyperactive immune systems. Vitamin D strengths innate immunity and prevents overactive immune responses. The finding could explain several mysteries, including why children are unlikely to die from COVID-19.
Sleep difficulties linked to altered brain development in infants who later develop autism
New research finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis, but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
Position statement addresses difficult issue: allocating scare resources in COVID-19 era
The COVID-19 pandemic has placed unprecedented pressure on societies worldwide, given the pandemic's rapid, often deadly spread. In health care, the pandemic has raised the pressing question of how society should allocate scarce resources during a crisis.
Most critically ill patients with COVID-19 survive with standard treatment, study reveals
Clinicians from two hospitals in Boston report that the majority of even the sickest patients with COVID-19 -- those who require ventilators in intensive care units -- get better when they receive existing guideline-supported treatment for respiratory failure.
Survey: Half of Americans concerned about new moms, babies being in public amid COVID-19
A new national U.S. survey finds that nearly 80 percent of respondents would be concerned about themselves or an expectant mother in their life in the midst of the current COVID-19 outbreak, with almost half expressing fear of going to a scheduled prenatal appointment.
Clay layers and distant pumping trigger arsenic contamination in Bangladesh groundwater
To avoid arsenic contamination, many Bangladeshi households access water via private wells drilled to 300 feet or less, beneath impermeable clay layers. Such clay layers have been thought to protect groundwater in the underlying aquifers from the downward flow of contaminants. However, a new study suggests that such clay layers do not always protect against arsenic, and could even be a source of contamination in some wells.
Police stop fewer black drivers at night when a 'veil of darkness' obscures their race
After analyzing 95 million traffic stop records, filed by officers with 21 state patrol agencies and 35 municipal police forces from 2011 to 2018, researchers concluded that 'police stops and search decisions suffer from persistent racial bias.'
Repurposing existing drugs for COVID-19 offers a more rapid alternative to a vaccine
Repurposing existing medicines focused on known drug targets is likely to offer a more rapid hope of tackling COVID-19 than developing and manufacturing a vaccine, argue an international team of scientists.
Middle age may be much more stressful now than in the '90s
A new study found that life may be more stressful now than it was in the 1990s, especially for people between the ages of 45 and 64.
Regularly attending religious services associated with lower risk of deaths of despair, study finds
People who attended religious services at least once a week were significantly less likely to die from 'deaths of despair,' including deaths related to suicide, drug overdose, and alcohol poisoning, according to new research.
Novel way to treat snakebite
Scientists demonstrate a completely new way of treating snakebites. The team have shown that the repurposing of an existing medicine, commonly used to treat mercury poisoning, is an effective oral therapy for the treatment of certain hemotoxic snakebites.
For better migraine treatment, try adding some downward dogs
Adding yoga to your regularly prescribed migraine treatment may be better than medication alone, according to a new study. The new research suggests yoga may help people with migraines have headaches that happen less often, don't last as long and are less painful.
Certain foods common in diets of US adults with inflammatory bowel disease
Foods, such as French fries, cheese, cookies, soda, and sports and energy drinks, are commonly found in the diets of United States adults with inflammatory bowel disease, according to a new study.
Unique 3D-images reveal the architecture of nerve fibers
Researchers have used synchrotron light to study what happens to the nerves in diabetes. The technique shows the 3D-structure of nerve fibers in very high resolution.
Tiny devices promise new horizon for security screening and medical imaging
Miniature devices that could be developed into safe, high-resolution imaging technology, with uses such as helping doctors identify potentially deadly cancers and treat them early, have been created.
среда, 6 мая 2020 г.
COVID-19 Critical Infrastructure Sector Response Planning
COVID-19 Critical Infrastructure Sector Response Planning
Could hotel service robots help the hospitality industry after COVID-19?
A new research study, investigating how service robots in hotels could help redefine leadership and boost the hospitality industry, has taken on new significance in the light of the seismic impact of the Covid-19 outbreak on tourism and hospitality.
Blueprint to protect the mental health of frontline medical workers
Researchers have developed a set of recommendations to manage the mental health of frontline medical workers during viral outbreaks, such as COVID-19.
Ultraviolet light exposes contagion spread from improper PPE use
In a new study, researchers vividly demonstrate how aerosol-generating procedures can lead to exposure of the contagion with improper PPE use. The most common error made by the health care workers was contaminating the face or forearms during PPE removal.
Mutations in SARS-CoV-2 offer insights into virus evolution
By analyzing virus genomes from over 7,500 people infected with COVID-19, researchers have characterized patterns of diversity of SARS-CoV-2 virus genome, offering clues to direct drugs and vaccine targets. The study identified close to 200 recurrent genetic mutations in the virus, highlighting how it may be adapting and evolving to its human hosts.
Neurology: Study finds 'volume dial' for turning neural communication up or down
Neuroscientists find that the protein Synaptotagmin 7 limits the supply of neurotransmitter-containing vesicles for release at synapses.
Metrics of cost-effective screening for type 1 diabetes
Health screenings can catch conditions early, helping patients avoid a condition's worst consequences or even preventing it from developing altogether. Think of mammograms to catch breast cancer early or high blood pressure screening before a person has a stroke. Screening helps pre-symptomatic patients take actions to reduce their risk of a catastrophic outcome.
Epidemiologists develop new tool for measuring the pace of aging across the life course
A study is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year. The tool - DunedinPoAm -- offers a unique measurement for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by changes to the environment.
Interim Guidance on Management of Coronavirus Disease 2019 (COVID-19) in Correctional and Detention Facilities
Guidance on preparing for, preventing, and managing the spread of COVID-19 in correctional and detention facilities.
Editing selfies is counter productive
Girls and young women shouldn't spend a lot of time editing selfies for social media because it negatively influences their thoughts about their looks, according to a new publication.
Operational Considerations for Personal Protective Equipment in the Context of Global Supply Shortages for Coronavirus Disease 2019 (COVID-19) Pandemic: non-US Healthcare Settings
Operational Considerations for Personal Protective Equipment in the Context of Global Supply Shortages for Coronavirus Disease 2019 (COVID-19) Pandemic: non-US Healthcare Settings
вторник, 5 мая 2020 г.
Healthcare Personnel and First Responders: How to Cope with Stress and Build Resilience During the COVID-19 Pandemic
Healthcare Personnel and First Responders: How to Cope with Stress and Build Resilience During the COVID-19 Pandemic
Employees: How to Cope with Job Stress and Build Resilience During the COVID-19 Pandemic
Employees: How to Cope with Job Stress and Build Resilience During the COVID-19 Pandemic
Factors to Consider When Planning to Purchase Respirators from Another Country
Factors to Consider When Planning to Purchase Respirators from Another Country
Small red blood cells could indicate cancer
Having abnormally small red blood cells - a condition known as microcytosis - could indicate cancer, according to new research.
Grandfamilies: New study uncovers common themes and challenges in kinship care
The opioid crisis and other social issues have left millions of US grandparents raising their grandchildren. A new study offers a framework to help social workers develop best practices for grandfamilies, addressing the relationship, situational, and emotional complexities of kinship care.
Genetic variation in a brain-cleansing water channel affects human sleep
The reason why we sleep remains an unresolved question of the 21st century. Research now shows that the depth of non-rapid-eye-movement (nonREM) sleep in humans is associated with different genetic versions of a gene that encodes a water channel involved in fluid flow in the brain.
Researchers develop chemistry needed to create marijuana breathalyzer
Chemists report the key chemical discovery necessary for the creation of a small, electronic marijuana breathalyzer.
Unraveling one of prion disease's deadly secrets
A professor of biochemistry and molecular biology report an unanticipated role for prion nucleation seeds that enhances their ability to appear and resist curing.
Genetic study ties higher alcohol consumption to increased stroke and PAD risk
Using genetic analysis, researchers found higher alcohol consumption increased risks for stroke and peripheral artery disease (PAD). Studies using genetic analysis don't rely on observational data, which often use self-reported data and could be subject to unreported risk factors.
Overlapping versions of our genetic history complicate precision medicine
The promise of personalized medicine has not fully materialized, say researchers, because the full sophistication of the genetic blueprint has a more complex and far-reaching influence on human health than scientists had first realized.
Long-term risks of hypertensive disorders during pregnancy impact more women
Twice as many women who experienced a hypertensive disorder during any of their pregnancies were at increased risk of developing heart or kidney diseases earlier in life based on incidence per woman versus per pregnancy, according to a new study.
Activating an estrogen receptor can stop pancreatic cancer cells from growing
Activating the G protein-coupled estrogen receptor (GPER) -- a receptor found on the surface of many normal and cancer tissues -- has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy. Researchers observed the effects of GPER activation in human and mouse pancreatic cancer models.
Sky-high surprise bills from air ambulance flights possible for many patients
When an emergency dispatcher calls for a helicopter to fly a critically ill patient to a hospital, they don't have time to check whether they take the patient's insurance. But after those patients land, 72% of them could face a potential 'surprise bill' because their ambulance provider isn't 'in network' with their insurance, a new study of people with private insurance finds. So could 79% of those transported via ground ambulance.
Extinguishing fearful memories depends on the flexibility of your DNA
New research shows that the ability to extinguish fearful memories relies on a change in DNA structure: from Z-DNA to B-DNA. The findings suggest that the more easily you can switch between DNA these structures, the more plastic your memory is.
Saving energy and lives: How a solar chimney can boost fire safety
Built as part of the sustainable features of a new Australian building, the specially-designed solar chimney radically boosts safe evacuation time in a fire - from 2 minutes to over 14 minutes.
понедельник, 4 мая 2020 г.
What to Do if Your Pet Tests Positive for the Virus that Causes COVID-19
What to Do if Your Pet Tests Positive for the Virus that Causes COVID-19
Riding the first wave of CDC's COVID-19 response at ports of entry
Riding the first wave of CDC's COVID-19 response at ports of entry
Ten Ways Healthcare Systems Can Operate Effectively during the COVID-19 Pandemic
Ten Ways Healthcare Systems Can Operate Effectively during the COVID-19 Pandemic
COVID-19 has unmasked significant health disparities in the U.S.
The COVID-19 pandemic has unmasked longstanding racial and ethnic health-related disparities, according to a new article. The essay notes higher rates of COVID-19 hospitalizations, deaths or positive cases among blacks, Hispanic/LatinX and Native Americans are being reported at local and national levels.
Two drugs show promise against COVID-19
Korean researchers have screened 48 FDA-approved drugs against SARS-CoV-2, and found that two, that are already FDA-approved for other illnesses, seem promising. The FDA approval for other uses would greatly reduce the time needed to gain FDA approval of use in COVID-19.
Study to determine incidence of novel coronavirus infection in U.S. children begins
A study to help determine the rate of novel coronavirus infection in children and their family members in the United States has begun enrolling participants. The study also will help determine what percentage of children infected with SARS-CoV-2, the virus that causes COVID-19, develop symptoms of the disease.
Activation of the SARS coronavirus 2 revealed
A viral spike protein mediates entry of SARS-CoV-2 into host cells and harbors an unusual activation sequence. This sequence is cleaved by the cellular enzyme furin and the cleavage is important for the infection of lung cells. These results define new starting points for therapy and vaccine research. In addition, they provide information on how coronaviruses from animals need to change in order to be able to spread in the human population.
Coronavirus SARS-CoV-2 infects cells of the intestine
Researchers have found that the coronavirus SARS-CoV-2, which causes COVID-19, can infect the cells of the intestine and multiply there. Using state-of-the-art cell culture models of the human intestine, the researchers have successfully propagated the virus in vitro, and monitored the response of the cells to the virus, providing a new cell culture model for the study of COVID-19.
Symptom-Based Strategy to Discontinue Isolation for Persons with COVID-19
Symptom-Based Strategy to Discontinue Isolation for Persons with COVID-19
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