As public aquatic venues open in some areas, CDC offers the following considerations for the safety of those who operate, manage, and use public pools, hot tubs, and water playgrounds.
четверг, 31 декабря 2020 г.
COVID-19 Vaccines and Severe Allergic Reactions
CDC has learned of reports that some people have experienced severe allergic reactions-also known as anaphylaxis-after getting a COVID-19 vaccine. As an example, an allergic reaction is considered severe when a person needs to be treated with epinephrine or EpiPen© or if they must go to the hospital. If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination site, seek immediate medical care by calling 911.
Asian tiger mosquito poses low risk for Zika virus outbreaks
The Asian tiger mosquito does not pose a major risk for Zika virus epidemics, according to a new study.
Protein twist and squeeze confers cancer drug resistance
Scientists have revealed how a transporter protein twists and squeezes compounds out of cells, including chemotherapy drugs from some cancer cells.
Returning to Work
Considerations for returning to work to make sure you protect yourself and other by practicing everyday preventive actions during the COVID-19 pandemic
Youth Sports Program FAQs
Answers to frequently asked questions about how to play sports safely during COVID-19.
Holiday Celebrations
When planning to host or attend a holiday celebration, consider the risk of getting or spreading COVID-19 during different activities.
COVID-19 Guidance for Shared or Congregate Housing
The following guidance was created to help owners, administrators, or operators of shared (also called “congregateâ€) housing facilities â€" working together with residents, staff, and public health officials â€" prevent the spread of COVID-19.
Food and Coronavirus Disease 2019 (COVID-19)
Currently, there is no evidence to suggest that handling food or consuming food is associated with COVID-19. But following good food safety practices can reduce the risk of illness from common foodborne pathogens.
Considerations for Non-emergency Vehicle Transportation for Tribal Communities During COVID-19
Precautions should be considered by tribal community members who may need to regularly share personal vehicles with members outside of their own households, including with those who are visibly sick, to minimize the risk of spreading COVID-19 when sharing non-emergency vehicle transportation.
Things to Know about the COVID-19 Pandemic
Five things that people need to know about COVID-19, including how to slow the spread, know their risk, protect themselves, what to do when sick, how to get testing, and what the symptoms are.
Considerations for Institutes of Higher Education
Explore CDC's considerations for institutes of higher education regarding COVID-19.
Social media safety messages: Pictures should match the words
When using social media to nudge people toward safe and healthy behaviors, it's critical to make sure the words match the pictures, according to a new study. After looking at social media posts, parents of young children were better able to recall safety messages such as how to put a baby safely to sleep when the images in the posts aligned with the messages in the text.
Study points the way to boost immunotherapy against breast cancer, other solid tumors
Researchers report that adding a small molecule to a chimeric antigen receptor-T (CAR-T) cell therapy can help immune system T cells to effectively attack solid tumors, such as breast cancers. The boost helps recruit more immune cells into battle at the tumor site, according to the new study.
Blood vessel cells implicated in chronic inflammation of obesity
When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity. Now, scientists have discovered a type of cell responsible, at least in mice, for triggering this inflammation in fat tissue. Their findings could eventually lead to new ways to treat obesity.
COVID-19 in Newly Resettled Refugee Populations
Refugees to the United States, especially those who are recently resettled, may be in living or working conditions that put them at higher risk of getting COVID-19.
Transfusions with higher red blood cell levels do not improve preterm baby outcomes
A randomized clinical trial is the largest study to-date to compare thresholds for blood transfusions in premature babies, offers guidance for health care providers.
How to Protect Yourself & Others
The best way to prevent COVID-19 infection is to avoid exposure to this virus and follow these everyday preventative actions.
When Vaccine is Limited, Who Gets Vaccinated First?
Because the supply of COVID-19 vaccine in the United States is expected to be limited at first, CDC recommends that initial supplies of COVID-19 vaccine be allocated to healthcare personnel and long-term care facility residents. CDC made this recommendation on December 3, 2020, and based it on recommendations from the Advisory Committee on Immunization Practices (ACIP), an independent panel of medical and public health experts.
Interim Guidance on Management of Coronavirus Disease 2019 (COVID-19) in Correctional and Detention Facilities
Guidance on preparing for, preventing, and managing the spread of COVID-19 in correctional and detention facilities.
Frequently Asked Questions
Most confirmed cases of COVID-19 reported from China have occurred in adults.
School Decision-Making Tool for Parents, Caregivers, and Guardians
Provides a tool to help parents, caregivers, and guardians weigh risks and benefits of in-person and virtual learning to decide how to send children back to school.
среда, 30 декабря 2020 г.
Cleaning And Disinfecting Your Home
As part of your everyday prevention actions clean and disinfect frequently touched surfaces and objects. For example: tables, countertops, light switches, doorknobs, and cabinet handles.
Shared and Congregate Housing
Ongoing mitigation guidance, mitigation guidance, and prevention and support for shared or congregate housing facilities.
How CDC Is Making COVID-19 Vaccine Recommendations
Learn about the CDC's COVID-19 vaccine recommendation process and the goals and principles guiding decisions if there is a limited supply at first.
Guidance for SARS-CoV-2 Point-of-Care Testing
This CDC webpage provides guidance on the regulatory requirements for SARS-CoV-2 POC testing, using POC tests safely, and information on reporting POC test results.
General Business Frequently Asked Questions
Find answers to frequently asked questions for businesses and employers of critical workers.
Information for Pediatric Healthcare Providers
Information when managing pediatric patients with confirmed or suspected COVID-19.
Potential new RX strategy for stroke
new research reports that a combination of a new drug and selected DHA derivatives is more effective in protecting brain cells and increasing recovery after stroke than a single drug.
A pursuit of better testing to sort out the complexities of ADHD
The introduction of computer simulation to the identification of symptoms in children with attention deficit/hyperactivity disorder (ADHD) has potential to provide an additional objective tool to gauge the presence and severity of behavioral problems, researchers suggest.
Living in or Visiting Retirement Communities or Independent Living Facilities
How residents living in retirement communities can protect themselves from COVID-19.
Considerations for Public Beaches
As some communities in the United States consider opening or begin to open public beaches, CDC offers the following considerations for steps beach managers can take to help protect their staff and beach visitors, both in the water and on land, and slow the spread of the virus that causes COVID-19.
Considerations for Traveling Amusement Parks and Carnivals
As traveling amusement park and carnival operations resume in some areas of the United States, CDC offers the following considerations.
Support For Teens and Young Adults
The outbreak of coronavirus disease 2019 (COVID-19) may be stressful. Teens and young adults may be feeling worried, bored, or frustrated. COVID-19 is frightening, but there are ways to manage your stress.
Interim Guidance for Case Investigation and Contact Tracing in K-12 Schools
Learn what administrators of public and private K-12 schools should know about COVID-19 case investigation and contact tracing.
вторник, 29 декабря 2020 г.
COVID-19 Published Science and Research
CDC is learning more about how COVID-19 spreads and affects people and communities. Read more about what we're finding out in our CDC publications, Morbidity and Mortality Weekly Report and Emerging Infectious Diseases.
Emerging SARS-CoV-2 Variants
Multiple SARS-CoV-2 variants are circulating globally, and several new variants emerged in the fall of 2020. Scientists are working to learn more about these variants to better understand how easily they might be transmitted and whether currently authorized vaccines will protect people against them. Currently, there is no evidence that these variants cause more severe illness or increased risk of death.
Science Briefs
CDC is learning more about how COVID-19 spreads and affects people and communities. Learn more by viewing scientific briefs and agendas.
Implications of the Emerging SARS-CoV-2 Variant VUI 202012/01
A new variant strain of SARS-CoV-2 that contains a series of mutations has been described in the United Kingdom (UK) and become highly prevalent in London and southeast England.
Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens for COVID-19
Health care providers should contact their local/state health department immediately to notify them of patients with fever and lower respiratory illness who they suspect may have COVID-19.
Considerations for Community-Based Organizations
CDC offers the following considerations for ways Community-Based Organizations (CBOs) can help protect individuals and communities and slow the spread of coronavirus disease 2019 (COVID-19).
Considerations for Events and Gatherings
Learn how to plan various size gatherings during COVID-19 to enhance the protection of individuals and communities.
Scientists develop high-throughput mitochondria transfer device
Scientists have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.
College football players underestimate risk of injury and concussion
College football players may underestimate their risk of injury and concussion, according to a new study.
Sustained cellular immune dysregulation in individuals recovering from COVID-19
Observational clinical research of COVID-19 patients can help clinicians better understand how the previously unknown SARS-CoV-2 virus acts, and findings from this research can better inform treatment and vaccine design.
General anesthesia and normal sleep affect brain in an amazingly similar way as consciousness fades
What happens in the brain when our conscious awareness fades during general anesthesia and normal sleep? Scientists studied this question with novel experimental designs and functional brain imaging. They succeeded in separating the specific changes related to consciousness from the more widespread overall effects, and discovered that the effects of anesthesia and sleep on brain activity were surprisingly similar. These novel findings point to a common central core brain network fundamental for human consciousness.
Summary for Healthcare Facilities: Strategies for Optimizing the Supply of PPE during Shortages
Summary Strategies to Optimize the Supply of PPE during Shortages
SARS-CoV-2 Viral Culturing at CDC
CDC Grows SARS-CoV-2, the virus that causes COVID-19, in Cell Culture
Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death.
A single gene 'invented' haemoglobin several times
Thanks to the marine worm Platynereis dumerilii, an animal whose genes have evolved very slowly, scientists have shown that while haemoglobin appeared independently in several species, it actually descends from a single gene transmitted to all by their last common ancestor.
Operating schools during COVID-19: CDC's Considerations
CDC offers considerations for ways in which schools can help protect students, teachers, administrators, and staff and slow the spread of COVID-19.
Suggestions for Youth and Summer Camps
CDC offers considerations for ways in which camp administrators can help protect campers, staff, and communities, and slow the spread of COVID-19.
Frequently Asked Questions about COVID-19 Vaccination
Answers to commonly asked questions about COVID-19 vaccines, including vaccine cost, availability, and types.
Brain imaging predicts PTSD after brain injury
Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder brought on by physical and/or psychological trauma. How its symptoms, including anxiety, depression and cognitive disturbances arise remains incompletely understood and unpredictable. Treatments and outcomes could potentially be improved if doctors could better predict who would develop PTSD. Now, researchers using magnetic resonance imaging (MRI) have found potential brain biomarkers of PTSD in people with traumatic brain injury (TBI).
Global trial reveals life saving drug for acute myeloid leukemia
Results from a global trial across 148 sites in 23 countries, showing a 30 per cent improvement in survival in patients with acute myeloid leukemia (AML), significantly improving survival in older patients, over the age of 55, with the disease. AML is the most acute blood cancer in adults and its incidence increases with age, with a poor prognosis.
Support for Veterans
Veterans may experience worry or anxiety about their risk for contracting COVID-19 or about their ability to get recommended care. Learn about actions veterans can take to help manage stress and anxiety.
Summary for Healthcare Facilities: Strategies for Optimizing the Supply of N95 Respirators during the COVID-19 Response
Checklist for Healthcare Facilities: Strategies for Optimizing the Supply of N95 Respirators during the COVID-19 Response
What to Expect at Your Appointment to Get Vaccinated for COVID-19
Because COVID-19 is a new disease with new vaccines, you may have questions about what happens before, during, and after your appointment to get vaccinated. These tips will help you know what to expect when you get vaccinated, what information your provider will give you, and resources you can use to monitor your health after you are vaccinated.
Common brain malformation traced to its genetic roots
Researchers have shown that Chiari 1 malformation can be caused by variations in two genes linked to brain development, and that children with large heads are at increased risk of developing the condition.
понедельник, 28 декабря 2020 г.
COVID-19 Questions and Answers: For People Who Use Drugs or Have Substance Use Disorder
People who use drugs or have substance use disorder and medical professionals can find information about drug use during the COVID-19 pandemic.
COVID-19 Parental Resources Kit - Young Adulthood
Young adults' social, emotional, or mental well-being may be impacted by the pandemic. Learn what you can do to help ensure their well-being.
COVID-19 Parental Resources Kit
Young people's social, emotional, or mental well-being may be impacted by the pandemic. Learn what you can do to help ensure their well-being.
Social Media Toolkit: COVID-19 & Mental Health
Provides messages and graphics to help ensure current, correct messaging from a trusted source, create collateral materials, and share resources regarding COVID-19.
COVID-19 Parental Resources Kit - Adolescence
Adolescents' social, emotional, or mental well-being may be impacted by the pandemic. Learn what you can do to help ensure their well-being.
Funeral Guidance for Individuals and Families
This guidance is for individuals and families as they work with funeral directors, community and religious leaders, and others to plan and safely hold funeral services and visitations during the COVID-19 pandemic.
Funeral Guidance for Individuals and Families
This guidance is for individuals and families as they work with funeral directors, community and religious leaders, and others to plan and safely hold funeral services and visitations during the COVID-19 pandemic.
Training for Healthcare Professionals
Healthcare professionals, find trainings on PPE use, nonpharmaceutical interventions, emergency preparedness and response, and more.
At-Home Testing
Learn more about how at-home testing and collection allow you to collect a specimen at home and either send it to a testing facility or perform the test at home.
Previous COVID-19 Forecasts: Hospitalizations
Learn about COVID-19 forecasts and modeling for new hospitalizations.
Discovery about how cancer cells evade immune defenses inspires new treatment approach
Researchers have learned how chromosomal instability allows cancer cells to avoid immune defenses and metastasize (spread). The discovery opens up potential new avenues for treatment.
National Wastewater Surveillance System (NWSS)
Learn about the National Wastewater Surveillance System, a new public health tool to understand COVID-19 spread in a community.
Vaping could cloud your thoughts, new studies suggest
Both adults and kids who vape were more likely to report difficulty concentrating, remembering, or making decisions than their non-vaping, non-smoking peers on two annual national surveys. Survey results also suggest that kids were more likely to experience mental fog if they started vaping before the age of 14.
Quick look under the skin
Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience. Artificial neural networks open up new possibilities: They require just seconds to interpret whole-body scans of mice and to segment and depict the organs in colors, instead of in various shades of gray. This facilitates the analysis considerably.
Music-induced emotions can be predicted from brain scans
Researchers have discovered what type of neural mechanisms are the basis for emotional responses to music. Altogether 102 research subjects listened to music that evokes emotions while their brain function was scanned with functional magnetic resonance imaging (fMRI).
Study suggests link between word choices and extraverts
Psychologists have found a link between extraverts and their word choices.
Chemists develop a new drug discovery strategy for 'undruggable' drug targets
A research team has developed a new drug discovery method targeting membrane proteins on live cells.
Switching DNA functions on and off by means of light
Biochemists have developed a new strategy for controlling the biological functions of DNA (deoxyribonucleic acid) by means of light and therefore provide a tool to investigate processes which take place in cells.
Do toddlers learning to spoon-feed seek different information from caregivers' hands and faces?
When toddlers begin to use a spoon to eat by themselves, what kind of interactions facilitate this behavior? To find out, an international research collaboration investigated the interactions between toddlers and their caregivers during mealtimes at a daycare center in Japan.
Strategies for Optimizing the Supply of Eye Protection
Purpose: This document offers a series of strategies or options to optimize supplies of eye protection in healthcare settings when there is limited supply. It does not address other aspects of pandemic planning; for those, healthcare facilities can refer to COVID-19 preparedness plans.
воскресенье, 27 декабря 2020 г.
New mammal reference genome helps ID genetic variants for human health
A new reference genome assembly identified more than 85 million genetic variants in the rhesus macaque, the largest database of genetic variation for any one nonhuman primate species to date.
суббота, 26 декабря 2020 г.
Discovery of aging mechanism for hematopoietic stem cells
By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells.
Protein tells developing cells to stick together
Scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system.
Astrocytes eat connections to maintain plasticity in adult brains
Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections -- the ones that are repeatedly introduced, such as how to avoid danger -- are nurtured and reinforced, while connections deemed unnecessary are pruned away. Adult brains undergo similar pruning, but it was unclear how or why synapses in the adult brain get eliminated. Now, a team of researchers has found the mechanism underlying plasticity and, potentially, neurological disorders in adult brains.
New research highlights the importance of a forgotten organ in ensuring healthy pregnancies
An international research team has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women.
COVID-19 Vaccination Considerations for Persons with Underlying Medical Conditions
If you have an underlying medical condition, this can help you make an informed decision about getting a COVID-19 vaccination.
пятница, 25 декабря 2020 г.
Requirement for Proof of Negative COVID-19 Test for All Air Passengers Arriving from the UK to the US
Requirement for Proof of Negative COVID-19 Test for All Air Passengers Arriving from the UK to the US
четверг, 24 декабря 2020 г.
COVID-19 severity affected by proportion of antibodies targeting crucial viral protein
COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study.
Mathematical modeling can help balance economy, health during pandemic
Using mathematical modeling, new interdisciplinary research determines the best course of action when it comes to walking the line between economic stability and the best possible health outcomes.
Breaking bad: How shattered chromosomes make cancer cells drug-resistant
Scientists describe how a phenomenon known as 'chromothripsis' breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth.
среда, 23 декабря 2020 г.
Scientists develop new gene therapy for deafness
A new study presents an innovative treatment for deafness, based on the delivery of genetic material into the cells of the inner ear. The genetic material 'replaces' the genetic defect and enables the cells to continue functioning normally. They maintain that this novel therapy could lead to a breakthrough in treating children born with various mutations that eventually cause deafness.
How our brains track where we and others go
A new study reveals how your brain navigates places and monitors someone else in the same location. The findings suggest that our brains generate a common code to mark where other people are in relation to ourselves.
Disposable surgical masks best for being heard clearly when speaking, study finds
Researchers have published the results of a new study evaluating the acoustic effects of face masks on speech. The team tested medical masks, disposable surgical masks, masks with clear plastic windows around the mouth, and homemade and store-bought cloth masks made of different fabric types and numbers of layers.
Similar factors cause health disparities in cancer, COVID-19
The same societal factors that have caused worse outcomes in cancer for some minority populations are now causing disparities in COVID outcomes. Potential policy changes could help improve outcomes for both diseases.
With COVID exacerbating superbug threat, researchers ID new weapon
Researchers have discovered a compound capable of pushing through barriers used by Gram-negative bacteria to resist antibiotics, damaging the bugs and preventing them from spreading.
Cost-effective hood reduces aerosol exposures to patients, otolaryngologists
A new study evaluates the efficacy of a prototype device that can be used during common otolaryngologic procedures that generate significant aerosols and droplets.
Why an early start is key to developing musical skill later in life
Is there, as some have suggested, a developmental period early in life when the brain is especially receptive to musical training? The answer, according to new research, is probably not.
The brain's protein factories at work
Protein synthesis is a finely tuned process in the cell by macromolecules known as ribosomes. Which regulators are responsible for controlling protein synthesis in the brain? To address this question, researchers studied the structure of the brain's ribosomal complexes in great detail. The team was able to identify a new factor which is also involved in controlling brain development.
Even after long-term exposure, bionic touch does not remap the brain
A new study by neuroscientists demonstrates that the brain does not remap itself even with long-term bionic limb use, posing challenges for the development of realistic prosthetic limbs.
When Vaccine is Limited, Who Gets Vaccinated First?
Because the supply of COVID-19 vaccine in the United States is expected to be limited at first, CDC recommends that initial supplies of COVID-19 vaccine be allocated to healthcare personnel and long-term care facility residents. CDC made this recommendation on December 3, 2020, and based it on recommendations from the Advisory Committee on Immunization Practices (ACIP), an independent panel of medical and public health experts.
Previous COVID-19 Forecasts: Cases
Forecasts show national and state level cumulative reported and predicted deaths since the beginning of the pandemic. CDC is working with partners to bring together weekly COVID-19 forecasts in one place.
Secondary bloodstream infections associated with severe COVID-19
People with severe COVID-19 and a secondary blood infection were significantly sicker upon hospital admission, had longer hospital stays and poorer outcomes, according to a new study.
Liquid bandage detects tissue oxygenation without the drawbacks of wired oximeters
A paint-on, transparent bandage containing phosphorescent materials reads the amount of oxygen reaching transplanted tissue -- a critical component of a transplant's success. Existing oximeter technology is complicated to use, restricts patients' movements, and is subject to false alarms. The first human trial of the liquid bandage in women undergoing breast reconstruction after cancer found that it performed as well as a wired oximeter device, the current clinical standard.
Increased meat consumption associated with symptoms of childhood asthma
Substances present in cooked meats are associated with increased wheezing in children, researchers report.
Controlling cardiac waves with light to better understand abnormally rapid heart rhythms
Over 300,000 people die each year in the US due to sudden cardiac death. In many cases, sudden cardiac death is caused by abnormally rapid heart rhythms called tachycardias, which means the heart cannot pump adequate blood to the body. In Chaos, researchers use mice to study tachycardias and find there are intrinsic mechanisms that exist in heart tissue that they hypothesize lead to the self-termination of rapid cardiac rhythm.
Cannabis use blunts stress reactivity in female rats
Female rats that inhaled vaporized cannabis daily for a month developed a blunted physiological response to stress, according to a new study. In contrast, male rats that were provided access to the same potency of cannabis over the same 30-day window did not experience any physiological changes in how they responded to a stressful situation.
Scientists discover mutations associated with early onset dementia
Scientists have announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition that manifests initially with psychiatric and behavioural changes in patients followed by a rapid progression of dementia in the third or fourth decade of life.
New mammogram measures of breast cancer risk could revolutionize screening
World-first techniques for predicting breast cancer risk from mammograms could revolutionize breast screening by allowing it to be tailored to women at minimal extra cost.
COVID-19 Forecasts: Hospitalizations
Learn about COVID-19 forecasts and modeling for new hospitalizations.
Previous COVID-19 Forecasts: Hospitalizations
Learn about COVID-19 forecasts and modeling for new hospitalizations.
вторник, 22 декабря 2020 г.
Model predicts where ticks, Lyme disease will appear next in Midwest states
By drawing from decades of studies, scientists created a timeline marking the arrival of black-legged ticks, also known as deer ticks, in hundreds of counties across 10 Midwestern states. They used these data - along with an analysis of county-level landscape features associated with the spread of ticks - to build a model that can predict where ticks are likely to appear in future years.
Mouse-controlled mouse helps researchers understand intentional control
Researchers have devised a brain machine interface (BMI) that allows mice to learn to guide a cursor using only their brain activity. By monitoring this mouse-controlled mouse moving to a target location to receive a reward, the researchers were able to study how the brain represents intentional control.
In shaky times, focus on past successes, if overly anxious, depressed
The more chaotic things get, the harder it is for people with clinical anxiety and/or depression to make sound decisions and to learn from their mistakes. On a positive note, overly anxious and depressed people's judgment can improve if they focus on what they get right, instead of what they get wrong, suggests a new study.
New method for imaging exhaled breath could provide insights into COVID-19 transmission
A new method for visualizing breath that is exhaled while someone is speaking or singing could provide important new insights into how diseases such as COVID-19 spread and the effectiveness of face masks.
Communication Toolkit
Translated COVID-19 prevention messages for migrants, refugees, and other limited-English-proficient populations, to reach them in their native languages.
Anti-diarrhea drug drives cancer cells to cell death
In cell culture, loperamide, a drug commonly used against diarrhea, proves effective against glioblastoma cells. A research team has now unraveled the drug's mechanisms of action of cell death induction and - in doing so - has shown how this compound could help attack brain tumors that otherwise are difficult to treat.
Neuroscientists isolate promising mini antibodies against COVID-19 from a llama
Researchers have isolated a set of promising, tiny antibodies, or 'nanobodies,' against SARS-CoV-2 that were produced by a llama named Cormac. Preliminary results suggest that at least one of these nanobodies, called NIH-CoVnb-112, could prevent infections and detect virus particles by grabbing hold of SARS-CoV-2 spike proteins. In addition, the nanobody appeared to work equally well in either liquid or aerosol form, suggesting it could remain effective after inhalation.
Evolution of a killer: How African Salmonella made the leap from gut to bloodstream
Scientists have exploited the combined power of genomics and epidemiology to understand how a type of Salmonella bacteria evolved to kill hundreds of thousands of immunocompromised people in Africa.
Implications of the Emerging SARS-CoV-2 Variant VUI 202012/01
A new variant strain of SARS-CoV-2 that contains a series of mutations has been described in the United Kingdom (UK) and become highly prevalent in London and southeast England.
New Variant of Virus that Causes COVID-19 Detected
Since November 2020, the United Kingdom (UK) has reported a rapid increase in COVID-19 cases in London and southeast England. This rapid increase in cases has been linked to a different version-or variant-of the virus that causes COVID-19 (SARS-CoV-2).
Antibiotics for C-sections effective after umbilical cord clamped
Antibiotics for cesarean section births are just as effective when they're given after the umbilical cord is clamped as before clamping - the current practice - and could benefit newborns' developing microbiomes, according to new research. The study, by far the largest of its kind, challenges current recommendations for antibiotic use. Administering antibiotics after clamping does not increase the risk of infection at the site of C-section incisions, the study concludes.
Brain tissue yields clues to causes of PTSD
A post-mortem analysis of brain tissue from people who had been diagnosed with post-traumatic stress disorder (PTSD) may help explain enduring mysteries about the disorder, such as why women are more susceptible to it and whether a dampened immune system response plays a role in dealing with stress, a team has found.
High-five or thumbs-up? New device detects which hand gesture you want to make
A new device developed by engineers can recognize hand gestures based on electrical signals detected in the forearm. The system, which couples wearable biosensors with artificial intelligence (AI), could one day be used to control prosthetics or to interact with almost any type of electronic device.
How to be happier in 2021
'If you want to make a New Year's resolution that really makes you happy, think about the ways in which you can contribute to the world, because the research shows it's not just good for the world but also really good for you,' says an international expert on motivational research.
Potential new drug target to treat cutaneous T cell lymphoma
In order to improve their understanding of how CTCL develops in hopes of developing new therapies, a team of scientists conducted a series of studies. They demonstrate that decreased expression of the protein SATB1 contributes to CTCL development and that drugs that cause SATB1 to become re-expressed may be potential treatment options for this disease.
Sex-specific Alzheimer's treatment could benefit males over females
A new study found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.
Diseased cell fragments burst from pockets in immune cells to activate response
Researchers have uncovered an important process in how our immune system detects signs of disease and activates a protective response. This understanding could improve efforts to find new and effective immunotherapy treatments for diseases like cancer.
понедельник, 21 декабря 2020 г.
COVID-19 Published Science and Research
CDC is learning more about how COVID-19 spreads and affects people and communities. Read more about what we're finding out in our CDC publications, Morbidity and Mortality Weekly Report and Emerging Infectious Diseases.
Citizens versus the internet: Confronting digital challenges with cognitive tools
Researchers recommend ways that psychological and behavioral sciences can help decrease the negative consequences of Internet use. These recommendations emphasize helping people gain greater control over their digital environments.
Gene pathway linked to schizophrenia identified through stem cell engineering
Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered.
Antigen tests -- are self-collected nasal swabs a reliable option?
Under certain conditions, antigen testing using self-collected swabs from the anterior nose may constitute a reliable alternative to antigen testing using nasopharyngeal swabs collected by health professionals.
Use of Masks to Help Slow the Spread of COVID-19
Use of Cloth Face Coverings to Help Slow the Spread of COVID-19
How one pain suppresses the other
When two painful stimuli act on us at the same time, we perceive one of them as less painful. This phenomenon is part of the body's own pain control system. A dysfunction of this inhibition is associated with chronic pain disorders.
Brain stem cells divide over months
Scientists have been able to observe the way stem cells in the adult brains of mice divide over the course of months to create new nerve cells. Their study shows that brain stem cells are active over a long period, and thus provides new insights that will feed into stem cell research.
Participate in Outdoor and Indoor Activities
Lower the likelihood of being exposed to COVID-19 by meeting people who don't live with you outdoors. Read options for indoor and outdoor activities.
New 3D maps reveal inner workings of immune cell gene expression
The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. Researchers have created 3D maps of how enhancer sequences and genes interact in several types of immune cells. Their new study opens the door to understanding individual risk for diseases from asthma to cancer.
Prostate cancer regulator plays role in COVID-19, providing a promising treatment lead
Clinical trials underway are testing whether drugs that target the androgen receptor -- successful in controlling prostate cancer -- could also work against the coronavirus.
California lockdown suppressed excess pandemic deaths
Nearly 20,000 more Californians died in the first six months of the pandemic than would have been expected to die in a normal year, with a disproportionate number of those deaths occurring among older adults, black or Latino residents, or those who had not completed high school, according to a new analysis.
Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens for COVID-19
Health care providers should contact their local/state health department immediately to notify them of patients with fever and lower respiratory illness who they suspect may have COVID-19.
Importance of COVID-19 Vaccination for Residents of Long-term Care Facilities
Vaccinating LTCF residents will save lives. Making sure LTCF residents can receive COVID-19 vaccination as soon as vaccines are available will help save the lives of those who are most at risk of dying from COVID-19. According to ACIP's recommendations, long-term care facility residents include adults who reside in facilities that provide a range of services, including medical and personal care, to persons who are unable to live independently. The communal nature of LTCFs and the population served (generally older adults often with underlying medical conditions) puts facility residents at increased risk of infection and severe illness from COVID-19
How to Wear Masks
Cloth face coverings are an additional step to help slow the spread of COVID-19 when combined with every day preventive actions and social distancing in public settings.
Cleaning and Disinfecting
Guidance for cleaning and disinfecting a public space, facility, or business to prevent the spread of COVID-19.
Learning from three centuries of smallpox epidemics in London, UK
The current COVID-19 pandemic has caused a surge of interest in the study of infectious disease transmission, and how control measures could change the course of the pandemic. New research examines the history of recorded smallpox epidemics in London.
Traditional model for disease spread may not work in COVID-19
A mathematical model that can help project the contagiousness and spread of infectious diseases like the seasonal flu may not be the best way to predict the continuing spread of the novel coronavirus, especially during lockdowns that alter the normal mix of the population.
The mechanics of the immune system
Not only chemistry plays a role in the docking of antigens to the T-cell; micromechanical effects are important too. Submicrometer structures on the cell surface act like microscopic tension springs. Tiny forces that occur as a result are likely to be of great importance for the recognition of antigens. It has now become possible to observe these forces directly using highly developed microscopy methods.
How cancers hurt themselves to hurt immune cells more
A study of melanoma cells explains a puzzling response they exhibit to ward off T cell attacks.
Difference in blood pressure between arms linked to greater early death risk
Robust evidence from a large international study confirms that a difference in blood pressure readings between arms is linked to greater risk of heart attack, stroke and death.
Exposure to metals can impact pregnancy
Exposure to metals such as nickel, arsenic, cobalt and lead may disrupt a woman's hormones during pregnancy, according to a new study.
Targeting the deadly coils of Ebola
Computer simulations of the Ebola virus structure are helping to crack its defenses. Ebola virus nucleocapsid stability conferred by RNA electrostatic interactions.
Drinking milk while breastfeeding may reduce the child's food allergy risk
Children of mothers who drink relatively more cow's milk during breastfeeding are at reduced risk of developing food allergies.
Ventilation
CDC recommends a layered strategy to reduce exposures to SARS-CoV-2, the virus that causes COVID-19. This includes using multiple mitigation strategies with several layers of safeguards to reduce the spread of disease and lower the risk of exposure.
COVID-19 in Newly Resettled Refugee Populations
Refugees to the United States, especially those who are recently resettled, may be in living or working conditions that put them at higher risk of getting COVID-19.
Medical oddity reveals unheard-of 'immunity gene' mutations and new way to screen them
Researchers baffled by an infant's rare encephalitis case unusual in children found unheard-of mutations and a new way to examine the 'immunity gene.'
воскресенье, 20 декабря 2020 г.
Long non-coding RNA may play a key role in cardiovascular disease
Through utilization of genetically modified high-risk atherosclerotic mice, researchers have identified and characterized Macrophage-Associated Atherosclerosis lncRNA Sequence (MAARS), which is expressed specifically in macrophages in atherosclerotic plaques and contributes to the progression of the disease.
Different COVID-19 Vaccines
Overview of what you should know about the different COVID-19 vaccines, including vaccine types and how they work to provide protection against COVID-19, which vaccines have been authorized and recommended in the United States, and which are in Phase 3 clinical trials.
The incredible, variable bacteria living in your mouth
Researchers have examined the human oral microbiome and discovered tremendous variability in bacterial subpopulations living in certain areas of the mouth. In many cases, the team was able to identify a handful of genes that might explain a particular bacterial group's habitat specificity.
Low-income preschoolers exposed to nurturing care have with higher IQ scores later on
Preschoolers living in impoverished communities who have access to a nurturing home environment have significantly higher intelligence quotient (IQ) scores in adolescence compared to those raised without nurturing care.
Living environment affects the microbiota and health of both dogs and their owners
In urban environments, allergic diseases are more common among dogs and their owners compared to those living in rural areas. Simultaneous allergic traits appear to be associated with the microbes found in the environment, but microbes relevant to health differ between dogs and humans.
суббота, 19 декабря 2020 г.
New insights into cholera microbe and chances of pandemic strain
Researchers have uncovered a novel way in which Vibrio cholerae, the aquatic microbe that causes cholera, may increase its competitive fitness, and the likelihood of creating pandemic strains of the bacteria.
The mask matters: How masks affect airflow, protection effectiveness
A computer model deepens our understanding of airflow while wearing face masks, where particles land in the respiratory tract and the effectiveness of three-layer surgical masks.
SARS-CoV-2-like particles very sensitive to temperature
A new study found that moderate temperature increases on glass surfaces broke down SARS-CoV-2 virus-like particles structure, while humidity had very little impact. The findings suggest that as temperatures begin to drop, particles on surfaces will remain infectious longer.
Researchers use artificial intelligence to ID mosquitoes
Rapid and accurate identification of mosquitoes that transmit human pathogens such as malaria is an essential part of mosquito-borne disease surveillance. Now, researchers have shown the effectiveness of an artificial intelligence system -- known as a Convoluted Neural Network -- to classify mosquito sex, genus, species and strain.
COVID-19 pandemic had big impact on commercial fishing in Northeast
With restaurants and supply chains disrupted due to the global coronavirus pandemic, two-fifths of commercial fishermen surveyed from Maine through North Carolina did not go fishing earlier this year, according to a new study that also documented their resilience and adaptation. Of those who kept fishing, nearly all reported a decline in income compared with previous years, according to the survey of 258 fishers in the Northeast.
Researchers create model to calculate COVID-19 health outcomes
Researchers have created a machine-learning model to predict the probability that a COVID-19 patient will need a ventilator or ICU care. The tool is free and available online for any healthcare organization to use.
At-Home Testing
Learn more about how at-home testing and collection allow you to collect a specimen at home and either send it to a testing facility or perform the test at home.
Potentially damaging surface ozone levels rose in lockdown, UK study finds
A new study finds that less traffic on the roads during the first lockdown led to a reduction in air pollution but may have caused potentially damaging surface ozone levels to rise.
COVID-19 Vaccines and Severe Allergic Reactions
CDC has learned of reports that some people have experienced severe allergic reactions-also known as anaphylaxis-after getting a COVID-19 vaccine. As an example, an allergic reaction is considered severe when a person needs to be treated with epinephrine or EpiPen© or if they must go to the hospital. If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination site, seek immediate medical care by calling 911.
What to Expect after Getting a COVID-19 Vaccine
COVID-19 vaccination will help protect you from getting COVID-19. You may have some side effects, which are a normal sign that your body is building protection. These side effects may affect your ability to do daily activities, but they should go away in a few days.
What to Expect at Your Appointment to Get Vaccinated for COVID-19
Because COVID-19 is a new disease with new vaccines, you may have questions about what happens before, during, and after your appointment to get vaccinated. These tips will help you know what to expect when you get vaccinated, what information your provider will give you, and resources you can use to monitor your health after you are vaccinated.
Researchers propose process to detect and contain emerging diseases
A global team of researchers is developing a strategy to detect and intercept diseases emerging from wildlife in Africa that could eventually infect humans.
Scientists get the most realistic view yet of a coronavirus spike's protein structure
A new study, done on a mild-mannered relative of the virus that causes COVID-19, paves the way for seeing more clearly how spike proteins initiate infections, with an eye to preventing and treating them.
Concern about loved ones might motivate people to mask up and get vaccine
In a recent survey, people who said social distancing and COVID-safety guidelines violated their personal freedoms responded more positively to these ideas when they felt a loved one might be at risk of severe illness for COVID-19.
Prenatal testing has halved the number of babies born with Down syndrome in Europe, study finds
A new study finds that the growth of prenatal screening in Europe has reduced the number of babies being born per year with Down syndrome (DS) by an average of 54 percent.
Stroke and altered mental state increase risk of death for COVID-19 patients
People hospitalized with COVID-19 and neurological problems including stroke and confusion, have a higher risk of dying than other COVID-19 patients, according to a new study. These findings have the potential to identify and focus treatment efforts on individuals most at risk and could decrease COVID-19 deaths.
How does the brain manage its learning?
Scientists reveal a critical role for a brain area called the perirhinal cortex in managing this learning process.
Nanotechnology: Nanoparticles as weapons against cancer
Researchers have developed a novel type of nanoparticle that efficiently and selectively kills cancer cells, thus opening up new therapeutic options for the treatment of tumors.
CAPTUREing Whole-Body 3D movements
Neuroscientists have made major advances in their quest to study the brain; however, there are no tools to precisely measure the brain's principal output -- behavior -- in freely moving animals. Researchers present CAPTURE, a new method for long-term continuous three-dimension motion tracking in freely behaving animals. Attaching markers to rats' head, trunk, and limbs, researchers can use CAPTURE to record the animal's natural behavior continuously for weeks.
New way to deliver DNA-based therapies for diseases
Researchers have created a new polymer to deliver DNA and RNA-based therapies for diseases. For the first time in the industry, the researchers were able to see exactly how polymers interact with human cells when delivering medicines into the body. This discovery opens the door for more widespread use of polymers in applications like gene therapy and vaccine development.
AI-supported test predicts eye disease three years before symptoms
A pioneering new eye test may predict wet AMD, a leading cause of severe sight loss, three years before symptoms develop, finds a new study.
пятница, 18 декабря 2020 г.
Frequently Asked Questions about COVID-19 Vaccination
Answers to commonly asked questions about COVID-19 vaccines, including vaccine cost, availability, and types.
8 Things to Know about Vaccine Planning
Learn the 8 things you need to know about where U.S. COVID-19 vaccination plans since a vaccine may become available before the end of the year.
Vaccines
Learn about COVID-19 vaccine planning, how vaccine recommendations will be made, and the work going into ensuring the safety of COVID-19 vaccines.
COVID-19 in Children and Teens
What you need to know about COVID-19 in children and teens, and what you can do if your child gets sick.
How CDC Is Making COVID-19 Vaccine Recommendations
Learn about the CDC's COVID-19 vaccine recommendation process and the goals and principles guiding decisions if there is a limited supply at first.
Fibrous protein finding may lead to improved bioprinting, tissue engineering
Fibrous proteins such as collagen and fibrinogen form a thin solid layer on the surface of an aqueous solution similar to the 'skin' that forms on warm milk, according to a team of Penn State Researchers, who believe this finding could lead to more efficient bioprinting and tissue engineering.
Growing human organs for transplantation with new proof-of-concept
With the number of people who suffer from organ failures and the growing need for available organs for transplant, finding a new way to provide organs and therapeutic options to transplant patients is a critical need. In a new article, researchers show for the first time that newly established stem cells from pigs could provide a solution, laying the groundwork for growing transplantable human organs.
Protein linked to progressive lung scarring in scleroderma patients
Osteopontin is discovered as the culprit behind systemic sclerosis patients' main cause of death: lung fibrosis. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.
Green revolution saved over 100 million infant lives in developing world
New research shows that since modern crop varieties were introduced in the developing world starting in 1961, they have substantially reduced infant mortality, especially for male babies and among poor households.
Exercise for low back pain beneficial but no one agrees on why
A new evidence review has found there is still no consensus between researchers about why exercise works for low back pain patients - despite decades of studies on the topic.
COVID-19 Vaccination for People Experiencing Homelessness: Frequently Asked Questions
COVID-19 vaccination FAQs for people experiencing homelessness
Interim Considerations for Institutions of Higher Education Administrators for SARS-CoV-2 Testing
Monitor and evaluate wearing masks as a community mitigation strategy for COVID-19 with CDC's action guide.
Considerations for Traveling Amusement Parks and Carnivals
As traveling amusement park and carnival operations resume in some areas of the United States, CDC offers the following considerations.
Strategies for Protecting K-12 School Staff from COVID-19
Learn strategies for protecting K-12 school staff from COVID-19 as schools reopen.
Considerations for Restaurants and Bars
CDC offers considerations for ways in which operators can protect employees, customers, and communities and slow the spread of COVID-19.
Can mammogram screening be more effective?
Economists have identified an important challenge in designing age-related guidelines for when to start breast cancer screenings: Women who start getting mammograms at age 40 may be healthier than the population of 40-year-old women as a whole, with a lower incidence of breast cancer at that age.
Errant DNA boosts immunotherapy effectiveness
DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two new studies indicate. The findings suggest that delivering radiation - which triggers DNA release from cells - before immunotherapy could be an effective way to fight cancers that are challenging to treat.
Optogenetic method can reveal how gut microbes affect longevity
Optogenetics offers a direct way to manipulate gut bacterial metabolism in a temporally, quantitatively and spatially controlled manner and enhance host fitness.
Considerations for Casinos and Gaming Operations
As some casinos and gaming operations resume in some areas of the United States, CDC offers the following considerations for ways in which casino and gaming operators can help protect staff and customers and slow the spread of COVID-19.
Guidance for Direct Service Providers
CDC has published guidance to support Direct Service Providers (DSPs), including personal care attendants, direct support professionals, paraprofessionals, therapists, and others as they support people with disabilities for COVID-19.
If You Are Immunocompromised, Protect Yourself From COVID-19
People with weakened immune systems are at higher risk of getting severely sick from SARS-CoV-2, the virus that causes COVID-19. If you are immunocompromised, the best way to prevent COVID-19 is to avoid being exposed to this virus. Learn about the steps you can take to protect your health.
People with Developmental and Behavioral Disorders
People with developmental and behavioral disorders and those who care for them can take steps to prevent illness and stay healthy during the COVID-19 pandemic.
Healthcare Personnel and First Responders: How to Cope with Stress and Build Resilience During the COVID-19 Pandemic
Healthcare personnel and first responders, learn how to cope with stress and build resilience during COVID-19.
Youth Experiencing Homelessness
Provide guidance to homeless youth so they can protect themselves and others from COVID-19.
четверг, 17 декабря 2020 г.
Especially neurotic people feel worse emotionally during the coronavirus crisis
New research finds that during the coronavirus crisis, neurotic people experience more negative emotions in their everyday lives, are more unstable emotionally and worry more about their health.
Study reports drop in lung cancer screening, rise in malignancy during COVID-19 surge
Reporting on how deferred care worsened outcomes for lung cancer patients when the COVID-19 pandemic first surged in the spring of 2020, researchers explained that they have identified a framework that could help people with serious health conditions keep up their appointments during the current surge.
COVID-19 escalated armed conflicts in several war-torn countries
A new study finds that armed conflict activities increased in five countries during the first wave of the coronavirus (COVID-19) pandemic.
Interim SARS-CoV-2 Testing Guidelines for Patients in Outpatient Hemodialysis Facilities
Testing Guidelines for patients undergoing outpatient hemodialysis
Genes could be key to new COVID-19 treatments, study finds
Genes involved in two molecular processes -- antiviral immunity and lung inflammation -- were pinpointed in new research. The breakthrough will help doctors understand how COVID-19 damages lungs at a molecular level.
How has the COVID-19 pandemic affected measles vaccination rates?
Researchers evaluated changes in measles vaccination rates from before the pandemic to this summer, when return for clinical care was encouraged. Finding a steep and lasting decline, the researchers are making efforts to improve timely vaccination and provide safe catch-up opportunities to children in their pediatric primary care network.
Coronavirus spread during dental procedures could be reduced with slower drill rotation
Researchers have found that careful selection and operation of dental drills can minimize the spread of COVID-19 through aerosols.
Reliable COVID-19 test could reduce virus spread
A unique test that targets three viral genes to increase reliability could cut COVID-19 detection time to 20 minutes, according to a new study.
Things to Know about the COVID-19 Pandemic
Five things that people need to know about COVID-19, including how to slow the spread, know their risk, protect themselves, what to do when sick, how to get testing, and what the symptoms are.
Stress and Coping
The COVID-19 outbreak may be stressful for people and may cause strong emotions in adults and children. Find ways you and your family can reduce stress.
Men over 50 have same success with vasectomy reversal outcomes as younger men
In good news for older men, a new study shows that men over 50 who undergo a vasectomy reversal had the same rate of pregnancy with their partners as their younger counterparts.
Oral contraceptive pills protect against ovarian and endometrial cancer
A comprehensive study involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use.
COVID-19 Forecasts: Deaths
CDC works with partners to bring together weekly forecasts for COVID-19 deaths in one place. These forecasts have been developed independently and shared publicly. It is important to bring these forecasts together to help understand how they compare with each other and how much uncertainty there is about what may happen in the upcoming four weeks.
Previous COVID-19 Forecasts: Cases
Forecasts show national and state level cumulative reported and predicted deaths since the beginning of the pandemic. CDC is working with partners to bring together weekly COVID-19 forecasts in one place.
среда, 16 декабря 2020 г.
Understanding mRNA COVID-19 Vaccines
mRNA vaccines are a new type of vaccine to protect against infectious diseases. To trigger an immune response, many vaccines put a weakened or inactivated germ into our bodies. Not mRNA vaccines. Instead, they teach our cells how to make a protein-or even just a piece of a protein-that triggers an immune response inside our bodies. That immune response, which produces antibodies, is what protects us from getting infected if the real virus enters our bodies.
Potential treatment approach kills lymphoma while sparing healthy cells
Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.
Experimental vaccine can counter dangerous effects of synthetic cannabinoids
Made in clandestine laboratories and sold widely across the United States, the diverse class of drugs known as synthetic cannabinoids presents a growing public health threat. In a new study, scientists have devised a way to deactivate these designer drugs after they've been administered -- offering a potential path for treating addiction and overdose.
Researchers identify neurons that control nausea-like responses in mice
Researchers have identified neurons that regulate nausea-like responses in mice. When these neurons are experimentally turned on, nausea-like responses can be activated regardless of exposure to nausea-triggering substances. Without these neurons, nausea-like responses to poisons are lost. The results shed light on the sensation of nausea and present new targets for the design of improved, more precise antinausea medications.
Driving force behind cellular 'protein factories' identified
Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neuron disease.
Novel biomarkers predict the development of incident heart failure
Researchers have discovered several new biomarkers that are associated with incident heart failure. In a new study, several inflammatory biomarkers and cell energy metabolites were linked to an increased risk of incident heart failure.
Researchers expose power of enzyme on key immune cells
Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells. These findings could result in further studies into a target for asthma and allergies, and fundamental work exploring the formation of immunity itself.
Maternal diet during lactation shapes functional abilities of milk bacteria
The mother's diet while breastfeeding can shape the profile of human milk oligosaccharides (HMO), a type of complex carbohydrate in the mother's milk. Changing the HMOs, which are food and fodder for healthy microbes, in turn modifies the functional abilities of the milk microbiome.
New guideline supports behavioral, psychological treatments for insomnia
A new clinical practice guideline establishing recommendations for the use of behavioral and psychological treatments for chronic insomnia disorder in adults has been published.
Contact Tracing for COVID-19
This section provides steps and consideration that jurisdictions can use to develop a protocol for the tracing of close contacts.
Turning sweat against itself with a metal-free antiperspirant
Body odor is an unpleasant smell, produced when bacteria living on the skin break down the proteins in sweat. To avoid stinking, some people apply antiperspirants that clog sweat ducts with foreign materials, such as metals, to slow perspiration. As a step toward a more natural solution, researchers have turned sweat against itself using an evaporation-based approach in which the salts in sweat create a gel-like plug.
Despite decrease in recent years, rate of sledding-related injuries still concerning
A new study found that 220,488 patients were treated in U.S. emergency departments for injuries related to sledding from 2008 through 2017. Nearly 70% of these patients were children age 19 years and younger.
New salmonella proteins discovered
Only one small protein needs to be missing and salmonellae are no longer infectious. This was discovered in a study in which the pathogens were re-analysed using bioinformatics.
Considerations for Events and Gatherings
Learn how to plan various size gatherings during COVID-19 to enhance the protection of individuals and communities.
How hope can make you happier with your lot in life
New research finds that that having hope for the future can make you happier with your lot - and protect you from risky behaviors such as drinking and gambling.
Publications about COVID-19 for Laboratories
Publications from CDC lab professionals during the 2019 novel coronavirus outbreak.
Oh so simple: Eight genes enough to convert mouse stem cells into oocyte-like cells
By activating just eight genes for transcription factors, researchers have directly converted mouse stem cells into oocyte-like cells that mature and can even be fertilized like egg cells. In addition to giving new insight into egg cell development, the research may lead to a simple route for generating large amounts of oocyte cytoplasm for use in reproductive biology and medicine.
The human helpers of SARS-CoV-2
Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate. Scientists have examined the corresponding genes of the helper proteins in a large study.
New insights into Fragile X syndrome and the fetal brain
Researchers have revealed further insight into the fetal development of our brain and the potential causes of Fragile X syndrome (FSX).
New study links cadmium to more severe flu, pneumonia infections
High levels of cadmium, a chemical found in cigarettes and in contaminated vegetables, are associated with higher death rates in patients with influenza or pneumonia -- and may increase the severity of COVID-19 and other respiratory viruses, according to a new study.
CDC's Diagnostic Multiplex Assay for Flu and COVID-19 and Supplies
CDC's multiplex assay simultaneously detects influenza A virus, influenza B virus, and SARS-CoV-2, the virus that causes COVID-19.
Three pillars of mental health: Good sleep, exercise, raw fruits and veggies
Getting good quality sleep, exercising, and eating more raw fruits and vegetables predicts better mental health and well-being in young adults, a study has found.
Lipid identified in human breast milk may play important role in early childhood weight
A lipid metabolite called 12,13-diHOME is in human breast milk. The authors of the study propose that 12,13-diHOME, as well as linked pathway metabolites from breast milk, have a protective effect against obesity development in offspring. They also suggest that a single bout of maternal exercise may boost levels of the metabolite in breast milk and that may translate into benefits for offspring in terms of healthy growth and development.
The DNA regions in our brain that contribute to make us human
With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar. Understanding the biological features that make us human is part of a fascinating and intensely debated line of research. Researchers have developed a new approach to pinpoint, for the first time, adaptive human-specific changes in the way genes are regulated in the brain.
Type of sugar used to sweeten sheep milk kefir may improve consumer acceptance
The study of human emotions can be used to gauge the sensory acceptance of dairy products. A possible route to increase worldwide consumption of sheep milk kefir may be to improve its sensory acceptance, which can be a determining factor for its inclusion in daily diets. Scientists studied the effects of kefir sweetened with five different sugars on sensory acceptance and emotional profile in regular consumers of fermented dairy products.
Nearly half of young drivers are resuming driving just weeks after sustaining a concussion
Researchers found that nearly half of adolescents who sought specialty care for a concussion were back to driving when asked approximately two weeks after the injury, even though few had returned to exercise and sports.
COVID-19 preprint data rapidly influenced critical care practice
In a new research letter, researchers examine whether preprint data on the use of the corticosteroid dexamethasone influenced clinical practice in treating COVID-19 critical care patients throughout Australia.
An unexpected role for the brain's immune cells
A team has uncovered that microglial cells constantly survey the brain to prevent spontaneous seizures. These findings could offer a new way to intervene in Alzheimer's disease, epilepsy, and autism.
вторник, 15 декабря 2020 г.
An avocado a day keeps your gut microbes happy, study shows
Eating avocado as part of your daily diet can help improve gut health, a new study shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or 'gut.'
Poverty linked to higher risk of COVID-19 death, study suggests
People in the poorest areas are more likely to be affected by severe COVID-19 -- and to die from the disease -- than those in more affluent districts, according to a study of critical care units.
Air Travel Toolkit for Airline Partners
Communication Toolkit for Airlines to inform Travelers and Crew
Road Travel Toolkit for Transportation Partners
Communication Toolkit for Transportation Partners to Inform Road Travelers
Drug may boost vaccine responses in older adults
A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a new study shows.
RNA basic building block produced biocatalytically for the first time
Researchers succeed in the first enzyme-driven biocatalytic synthesis of nucleic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics.
Study IDs four things that make people feel good about using chatbots
A recent study has identified four factors that predict user satisfaction with customer service chatbots. The study also found that a positive chatbot experience was associated with customer loyalty, highlighting the potential importance of the findings to corporate brands.
Undruggable diseases gain a new RNA drug-discovery tool
A new RNA-targeting tool enables scientists to tackle difficult molecular recognition problems to aid drug discovery for incurable diseases.
Type and abundance of mouth bacteria linked to lung cancer risk in non-smokers
The type and abundance of bacteria found in the mouth may be linked to lung cancer risk in non-smokers. Fewer species and high numbers of particular types of bacteria seem to be linked to heightened risk, the findings indicate.
Genes play a role in common knee injury
It has long been known that the choice of shoe, surface and type of sport can all be contributing factors when someone suffers an anterior cruciate ligament rupture. Researchers have now observed that genes also play a decisive role.
Operational Considerations for Schools
Schools play an important role in educating students about disease prevention within their homes and communities. Many children and adolescents rely on key services provided by schools, such as school meal programs. Schools are considered safe havens for children who might be experiencing various forms of abuse or violence. This document provides suggestions for mitigating risks for COVID-19 transmission in schools in low-resource, international settings
Digital trackers for mental health not yet fit for purpose
Digital tracking of people with mental health conditions has the power to transform medical diagnostics and treatment, but its claims need careful scrutiny, says an expert in digital analytics.
Employees: How to Cope with Job Stress and Build Resilience During the COVID-19 Pandemic
Learn how to deal with and manage job stress during COVID-19.
Data-driven discovery of biomarkers pave way for improved diagnosis of contact allergy
With the help of algorithms, researchers have identified markers that can differentiate between irritant eczema and contact allergy, two skin reactions that look similar but require different treatment.
New insights about depression
New research reveals new insights about risk factors for depression based on data from a landmark longitudinal study focused on heart disease.
Research dispels fears human stem cells contain cancer-causing mutations
Pioneering new research has made a pivotal breakthrough that dispel concerns that human stem cells could contain cancer-causing mutations.
How to Select, Wear, and Clean Your Mask
COVID-19 spreads mainly from person to person through respiratory droplets produced when an infected person coughs, sneezes, or talks. These droplets can land in the mouths or noses of people who are nearby or possibly be inhaled into the lungs.
понедельник, 14 декабря 2020 г.
High blood pressure at any age, no matter how long you have it, may speed cognitive decline
Memory, concentration and other cognitive functions decline faster among middle-aged and older adults who have high blood pressure than those who do not. Even seemingly slight blood pressure elevation during middle and older age is linked to a faster decline in cognition.
Apathy could predict onset of dementia years before other symptoms
Apathy -- a lack of interest or motivation -- could predict the onset of some forms of dementia many years before symptoms start, offering a 'window of opportunity' to treat the disease at an early stage, according to new research.
A human gene placed in fruit flies reveals details about a human developmental disorder
Meier-Gorlin syndrome, or MGS, is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities. One mutation causing MGS, first reported in 2017, is a Lysine 23 to Glutamic acid (K23E) substitution in the gene for Orc6. Researchers have now put that mutant human gene into fruit flies to probe the function of Orc6 K23E.
Emerging from the fog: Little understood post-stroke cognitive issues are verified
For the first time, researchers have measured the physical evidence of diminished neural processing within the brain after a stroke.
Endothelial cell targeting could help fight COVID-19 symptoms, study shows
For COVID-19 patients with serious lung disease, targeting endothelial cells -- cells that comprise the blood vessel wall which regulate oxygen exchange between airways and the bloodstream -- may be a novel approach restoring normal lung function.
UV-emitting LED lights found to kill coronavirus
Researchers have shown that the coronavirus can be killed efficiently, quickly, and cheaply using ultraviolet (UV) light-emitting diodes (UV-LEDs). They believe that the UV-LED technology will soon be available for private and commercial use.
Compound derived from thunder god vine could help pancreatic cancer patients
The results of a pre-clinical study suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.
Robotic exoskeleton training improves walking in adolescents with acquired brain injury
Gait training using robotic exoskeletons improved motor function in adolescents and young adults with acquired brain injury.
Screening K-12 Students for Symptoms of COVID-19: Limitations and Considerations
Provides guidance to K-12 schools on how to screen for COVID-19 symptoms as part of reopening schools in fall 2020.
The Importance of COVID-19 Vaccination for Healthcare Personnel
Based on recommendations from the Advisory Committee on Immunization Practices (ACIP), an independent panel of medical and public health experts, CDC recommends healthcare personnel be among those offered the first doses of COVID-19 vaccines. Healthcare personnel include all paid and unpaid persons serving in healthcare settings who have the potential for direct or indirect exposure to patients or infectious materials.
How our brains know when something's different
Scientists discovered how a set of high frequency brain waves may help us unconsciously know when something's different by comparing memories of the past with present experiences.
Carrots are healthy, but active enzyme unlocks full benefits
Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you need an active enzyme to produce this vitamin.
Like adults, children by age 3 prefer seeing fractal patterns
By the time children are 3 years old they already have an adult-like preference for visual fractal patterns commonly seen in nature, according to researchers.
tRNA fragments are involved in post-stroke immune reactions
Following a stroke, the immune system triggers an inflammatory reaction that can either overshoot or turn into an immune deficiency. Now, a team of researchers has shown that tRNA fragments play a role in this immune reaction. Fragments of tRNAs, which transport amino acids during protein synthesis ('transfer RNA'), were long merely considered cellular waste. The researcher's aim: To find new target structures for therapeutics.
Challenges of fusing robotics and neuroscience
Combining neuroscience and robotic research has gained impressive results in the rehabilitation of paraplegic patients. A research team was able to show that exoskeleton training not only helped patients to walk, but also stimulated their healing process. With these findings in mind, a professor wants to take the fusion of robotics and neuroscience to the next level.
Strong social support decreases mental health problems in young adults
Early adulthood, a transitional life stage marked by major changes in social roles and responsibilities, can bring with it an increase of mental health problems.
Why 'lab-made' proteins have unusually high temperature stability
Efforts to enhance the ability of proteins to resist breaking down, or 'denaturing', at high temperatures is one of the hottest topics in biotech. Researchers have now identified some of the principles behind how this works, potentially opening up a raft of industrial applications for designer proteins.
воскресенье, 13 декабря 2020 г.
Rewiring stroke survivors brains could alleviate depression
Researchers have made a major breakthrough in the treatment of depression after stroke, using a high frequency brain stimulation device to improve low moods.
New analysis method for predicting the risks and effects of immunotherapy
In a new study, researchers have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukemia. This has awakened hopes that this analysis method could pave the way for important breakthroughs in immunotherapy research and treatment.
Artificial visual system of record-low energy consumption for the next generation of AI
Researchers have built an ultralow-power consumption artificial visual system to mimic the human brain, which successfully performed data-intensive cognitive tasks. Their experiment results could provide a promising device system for the next generation of artificial intelligence (AI) applications.
Different forms of sugar impact hunger-suppressing hormones in young adults
Drinks with sucrose compared to glucose may cause young adults to produce lower levels of appetite-regulating hormones, according to a new study.
Using CRISPR, new technique makes it easy to map genetic networks
Scientists have developed an easy way to genetically profile a cell, including human cells, and rapidly determine all DNA sequences in the genome that regulate expression of a specific gene. This can help track down upstream genes that regulate disease genes, and potentially find new drug targets. The technique involves 'CRISPRing' the entire genome while giving each CRISPR guide RNA a unique barcode. Deep sequencing of pooled cells uniquely identifies control genes.
Preschool program linked with better social and emotional skills years later
A preschool enrichment program helps boost social and emotional skills that still have positive effects years later during middle and high school, according to a new study.
Natural environmental conditions facilitate the uptake of microplastics into living cells
The environment is polluted by microplastics worldwide. A research team has now discovered that microplastic particles find their way into living cells more easily if they were exposed to natural aquatic environments, i.e. fresh water and seawater. Biomolecules occurring in the water are deposited on the microplastic surfaces, which promote the internalization of the particles into cells.
Bosses need appreciation, too
'Tis the season to be grateful, even for your boss, according to a recent A new study suggests that when supervisors feel appreciated, it gives them a boost of energy and optimism. In the end, that's good for employees and the organization's bottom line.
When it comes to feeling pain, touch or an itch, location matters
When you touch a hot stove, your hand reflexively pulls away; if you miss a rung on a ladder, you instinctively catch yourself. Both motions take a fraction of a second and require no forethought. Now, researchers have mapped the physical organization of cells in the spinal cord that help mediate these and similar critical 'sensorimotor reflexes.'
A potential therapy for one of the leading causes of heart disease
After 15 years of unrelenting work, a team of scientists has discovered a potential drug candidate for heart valve disease that works in both human cells and animals and is ready to move toward a clinical trial.
New and unexplored dimension in the study of protein-protein interactions
Cells accumulate glutamate and related molecules under stress, and so formation of high-order protein assemblies under these conditions has important biological implications. Specifically, this would represent a mechanism by which the presence of stressor compounds in the cell could control DNA replication.
Increased social media use linked to developing depression
Young adults who increased their use of social media were significantly more likely to develop depression within six months, according to a new national study.
10 Things Healthcare Professionals Need to Know about U.S. COVID-19 Vaccination Plans
Learn the 10 things healthcare professionals need to know about where U.S. COVID-19 vaccination planning currently stands.
When Vaccine is Limited, Who Gets Vaccinated First?
Because the supply of COVID-19 vaccine in the United States is expected to be limited at first, CDC recommends that initial supplies of COVID-19 vaccine be allocated to healthcare personnel and long-term care facility residents. CDC made this recommendation on December 3, 2020, and based it on recommendations from the Advisory Committee on Immunization Practices (ACIP), an independent panel of medical and public health experts.
What to Expect at Your Appointment to Get Vaccinated for COVID-19
Because COVID-19 is a new disease with new vaccines, you may have questions about what happens before, during, and after your appointment to get vaccinated. These tips will help you know what to expect when you get vaccinated, what information your provider will give you, and resources you can use to monitor your health after you are vaccinated.
Importance of COVID-19 Vaccination for Residents of Long-term Care Facilities
Vaccinating LTCF residents will save lives. Making sure LTCF residents can receive COVID-19 vaccination as soon as vaccines are available will help save the lives of those who are most at risk of dying from COVID-19. According to ACIP's recommendations, long-term care facility residents include adults who reside in facilities that provide a range of services, including medical and personal care, to persons who are unable to live independently. The communal nature of LTCFs and the population served (generally older adults often with underlying medical conditions) puts facility residents at increased risk of infection and severe illness from COVID-19
What to Expect after Getting a COVID-19 Vaccine
COVID-19 vaccination will help protect you from getting COVID-19. You may have some side effects, which are a normal sign that your body is building protection. These side effects may affect your ability to do daily activities, but they should go away in a few days.
Different COVID-19 Vaccines
Overview of what you should know about the different COVID-19 vaccines, including vaccine types and how they work to provide protection against COVID-19, which vaccines have been authorized and recommended in the United States, and which are in Phase 3 clinical trials.
Older Adults
Older adults, 65 years and older, are at higher risk for severe illness. COVID-19 is a new disease and we are learning more about it every day.
Information for Healthcare Professionals about Coronavirus (COVID-19)
Resources for Healthcare Professionals Caring for COVID-19 Patients
Post Vaccine Considerations for Healthcare Personnel
Considerations for Long-Term Care Residents following COVID-19 Vaccination.
Post Vaccine Considerations for Residents
Considerations for Long-Term Care Residents following COVID-19 Vaccination.
Nursing Homes and Long-Term Care Facilities
Information about COVID-19 in Nursing Homes and Long-Term Care Facilities
суббота, 12 декабря 2020 г.
Robots could replace real therapy dogs
Robotic animals could be the 'pawfect' replacement for our real-life furry friends, a new study has found.
Kids gain weight when new convenience stores open nearby
A new study found that changes in the food environment around low-income and high-ethnic/racial minority populations over time impact childhood obesity. Increased availability of small grocery stores selling a selection of healthy items in close proximity to children's homes improves their weight status over time, whereas increased availability of convenience stores selling predominantly unhealthy foods is likely to be detrimental.
Predicting heart disease from the skin
Researchers find that the genetic underpinnings of a skin disorder at birth indicate future heart problems.
Toxin provides clues to long-term effects of diarrhea caused by E. coli
A study has found that a toxin produced by E. coli changes intestinal cells to benefit itself, an ability that could provide a clue to why the bacteria have been linked to nutritional problems such as malnutrition and stunted growth.
Insecure livelihoods hindering efforts to combat anti-microbial resistance globally
Patients living in precarious circumstances are less likely to use antibiotics appropriately according to a new study, suggesting that efforts to improve conditions for those with little security in their livelihoods could have an unexpected benefit in helping to tackle antimicrobial resistance globally.
Frequently Asked Questions about COVID-19 Vaccination
Answers to commonly asked questions about COVID-19 vaccines, including vaccine cost, availability, and types.
How CDC Is Making COVID-19 Vaccine Recommendations
Learn about the CDC's COVID-19 vaccine recommendation process and the goals and principles guiding decisions if there is a limited supply at first.
8 Things to Know about Vaccine Planning
Learn the 8 things you need to know about where U.S. COVID-19 vaccination plans since a vaccine may become available before the end of the year.
Community Mitigation (Non-US Settings)
Suggestions for individuals, partners, and ministries of health to mitigate COVID-19 transmission in low-resource environments and considerations associated with each measure.
пятница, 11 декабря 2020 г.
Vaccines
Learn about COVID-19 vaccine planning, how vaccine recommendations will be made, and the work going into ensuring the safety of COVID-19 vaccines.
Toolkit for Community and Faith-Based Organizations
Guidance and tools to help community and faith-based organizations make decisions, protect their employees, volunteers, and members, and communicate with their communities.
What makes hard workouts so effective
High-intensity interval training strengthens the heart even more than moderate exercise does. Now researchers have found several answers to what makes hard workouts so effective.
Brains work harder while processing descriptions of motion in other languages
Different languages describe motion differently, according to distinct lexical rules. And though we may not consciously notice those rules, we follow them -- and researchers have found they affect how our brains perceive and process descriptions of physical movement.
Gut microbiota plays a role in brain function and mood regulation
Depression is a mental disorder that affects more than 264 million people of all ages worldwide. Understanding its mechanisms is vital for the development of effective therapeutic strategies. Scientists recently conducted a study showing that an imbalance in the gut bacterial community can cause a reduction in some metabolites, resulting in depressive-like behaviors. These findings show that a healthy gut microbiota contributes to normal brain function.
The pressure sensor of the venus flytrap
The display of a smartphone reacts to finger pressure. The carnivorous Venus flytrap, on the other hand, even notices when a lightweight like a fly lands on it. Special genes make this possible.
Persistence of Zika virus in the brain causes long-term problems in mice
The Zika virus can remain in mouse brain for extended periods, leading to long-term neurological and behavioral consequences, according to a new study.
Promising treatment for premenstrual dysphoric disorder, PMDD
The mental symptoms of premenstrual dysphoric disorder improve following treatment with a progesterone receptor modulator. The mechanism of action of the study drug provides insights into the potential molecular mechanisms underlying this disorder and its treatment.
Five-minute EEG recordings: A key to the symptoms of Parkinson's
Pathological changes related to the disability of Parkinson's patients can already be detected in signals from the scalp without the need to open the skull.
New guidelines for treating the complications of brain tumors
Experts have now compiled international guidelines and standards for the treatment of complications of brain tumors.
New biomarker candidate for amyotrophic lateral sclerosis
A research team has developed a diagnostic tool for the rare neurological disease amyotrophic lateral sclerosis (ALS). The study used the patented immuno-infrared sensor to analyze folding changes of proteins in the cerebrospinal fluid (CSF) of ALS patients after specific binding.
Toolkit for Shared and Congregate Housing
COVID-19 guidance and tools to help owners, administrators, or operators of shared housing facilities make decisions, protect, and communicate with residents, staff, and public health officials.
Hydrogels with fine-toothed molecular combs may make enduring glucose-monitoring implants
Scientists reported they have designed a hydrogel membrane that may be used to house optical glucose sensing materials, toward building a biosensor for monitoring sugar levels in diabetics.
COVID-19 Contact Tracing Communications Toolkit for Health Departments
This toolkit will help health departments develop their communications with communities about COVID-19 contact tracing.
Test your heart health by climbing stairs
Climbing four flights of stairs in less than a minute indicates good heart health, according to new research.
Scientists build whole functioning thymus from human cells
Researchers have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold. Their work is an important step towards being able to build artificial thymi which could be used as transplants.
Ability to predict C-diff mortality nearly doubled with new guidelines
Updated national guidelines for treating infections caused by the deadly superbug Clostridioides difficile (C. diff) have been examined and approved.
Within a hair's breadth -- forensic identification of single dyed hair strand now possible
A single strand of hair in a crime scene contains many clues that can help identify a perpetrator. In a recent study, scientists have combined two modern techniques, called surface-enhanced Raman spectroscopy and X-ray fluorescence, to distinguish between different colors in individual hair strands. Both these techniques are almost non-destructive and can be conducted with portable devices, making this a promising way to get supportive evidence in forensic investigations.
Winter Holidays
Winter holiday gatherings with family and friends are fun but can increase the chances of getting or spreading COVID-19 or the flu. Follow these tips to make your winter holidays safer.
четверг, 10 декабря 2020 г.
Diet modifications - including more wine and cheese - may help reduce cognitive decline
The foods we eat may have a direct impact on our cognitive acuity in our later years, according to new research. The study is the first of its kind to connect specific foods with cognitive decline. The findings show cheese protected against age-related cognitive problems and red wine was related to improvements in cognitive function.
Blocking protein restores strength, endurance in old mice
A single protein is a master regulator of mouse muscle function during aging, a new study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.
Embryonic development in a petri dish
By growing mouse stem cells in a special gel, a research team succeeded to grow structures similar to parts of an embryo. The trunk-like structures develop the precursors for neural, bone, cartilage and muscle tissues from cellular clumps within five days. This could allow the investigation of the effects of pharmacological agents more effectively in the future -- and on a scale that would not be possible in living organisms.
New algorithm will prevent misidentification of cancer cells
Researchers have developed a computer algorithm that can identify differences in cancer cell lines based on microscopic images, a unique development towards ending misidentification of cells in laboratories.
Ferrets, cats and civets most susceptible to coronavirus infection after humans
An analysis of ten different species finds that humans -- followed by ferrets and, to a lesser extent cats, civets and dogs -- are the most susceptible animals to SARS-CoV-2 infection.
Human egg cells are imperfect surprisingly often
More than 7% of human oocytes contain at least one exchangeless chromosome pair, demonstrating a remarkably high level of meiotic recombination failure, finds a new study. The findings suggest that right from the get-go of human egg cell development, a striking proportion of oocytes are predestined to be chromosomally abnormal. But the frequency of exchangeless chromosomes is not affected by maternal age.
A gene from ancient bacteria helps ticks spread Lyme disease
One reason ticks spread Lyme disease so well goes back to a unique evolutionary event. Researchers discovered that an antibacterial enzyme in ticks, Dae2, protects them from bacteria found on human skin, while still allowing them to harbor Borrelia burgdorferi, the bacterium that causes Lyme disease. Ticks acquired the gene for this enzyme 40 million years ago from an unknown species of ancient bacteria.
Inhaled vaccine induces fast, strong immune response in mice and non-human primates
Researchers demonstrate in a new study that a phage-based inhalation delivery system for vaccines generates potent antibody responses in mice and non-human primates, without causing lung damage. The findings suggest that a safe and effective lung delivery system could one day be used for vaccines and therapeutics against respiratory diseases.
Health Equity
Systemic health and social inequities have put people from racial and ethnic minority groups at increased risk from COVID-19. Take steps to reduce health disparities.
Operational Considerations for Adapting a Contact Tracing Program to Respond to the COVID-19 Pandemic
Contact tracing is a key component of controlling transmission of infectious diseases. This document is for CDC country offices, ministries of health, sub-national public health authorities, and other implementing partners in non-US settings. While select adaptations may be relevant for any jurisdiction, the document focuses on adaptations that might be especially useful in low- and middle-income countries.
Social Media Toolkit
Provides messages and graphics to help ensure current, correct messaging from a trusted source, create collateral materials, and share resources regarding COVID-19.
Natural antibiotics produced in wounds increase sleep and survival after injury
When wounded, our body sets off a complex immune response. As part of it, the wound produces small antimicrobial molecules to fight off the pathogens locally. Researchers have found that these natural antibiotics can also act as long-range molecular messengers.
Considerations for Use of SARS-CoV-2 Antigen Testing in Nursing Homes
SARS-CoV-2 Antigen Testing in Nursing Homes
CDC's Diagnostic Test for COVID-19 Only and Supplies
How to Get CDC's COVID-19 Diagnostic Test and Supplies
Using light, red blood cells and a honey bee peptide to deliver therapeutic proteins
Protein therapies are often more potent and selective toward their biochemical targets than other types of drugs, particularly small molecules. However, proteins are also more likely to be quickly degraded by enzymes or cleared from blood by the kidneys, which has limited their clinical use. Now, researchers have engineered red blood cell (RBC) carriers that release therapeutic proteins when stimulated by light, with the help of a honey bee peptide.
Exercise may protect bone health after weight loss surgery
Although weight loss surgery is a highly effective treatment for obesity, it can be detrimental to bone health. A new study suggests that exercise may help address this shortcoming.
The use of wild mammals in traditional medicine
Investigators identified 565 mammalian species that have been used to source products used in traditional medicine around the world, especially in Asia, Africa, and Latin America.
среда, 9 декабря 2020 г.
Previous Forecasts of Total Deaths
Forecasts show national and state level cumulative reported and predicted deaths since the beginning of the pandemic.
COVID-19 Forecasts: Deaths
CDC works with partners to bring together weekly forecasts for COVID-19 deaths in one place. These forecasts have been developed independently and shared publicly. It is important to bring these forecasts together to help understand how they compare with each other and how much uncertainty there is about what may happen in the upcoming four weeks.
Researchers develop rapid genomics strategy to trace coronavirus
A team of researchers is pioneering the use of a fast genomic sequencing technology to help determine the source of hard-to-trace coronavirus cases.
New compound related to psychedelic ibogaine could treat addiction, depression
A non-hallucinogenic version of the psychedelic drug ibogaine, with potential for treating addiction, depression and other psychiatric disorders, has been developed by researchers.
Youth depression tied to higher risk of 66 diseases and premature death
Depressed children and teenagers have an increased risk of suffering from premature death and a wide range of illnesses later in life. That is according to a large observational study. The findings highlight the need to look for other potential diseases following childhood or adolescent depression. Other psychiatric conditions, such as anxiety and substance misuse, can explain part of the association.
Study connects diabetes, air pollution to interstitial lung disease
People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate. These findings are especially important today in the midst of the COVID-19 pandemic, where there is a heightened concern for the convergence of health effects from air pollution and SARS-CoV-2 in susceptible populations.
Wielding a gun makes a shooter perceive others as wielding a gun, too
Nearly a decade ago, cognitive psychologist Jessica Witt wondered if the mere act of wielding a firearm could bias someone to perceive another person as wielding one, too -- and more importantly, if such a bias could be scientifically measured. A series of experiments later, Witt and her research team concluded, yes and yes. The team has recently published a new set of experiments further underscoring what they call the 'gun embodiment effect'.
Previous COVID-19 Forecasts: Hospitalizations
Learn about COVID-19 forecasts and modeling for new hospitalizations.
COVID-19 Forecasts: Hospitalizations
Learn about COVID-19 forecasts and modeling for new hospitalizations.
Toolkit for People 15 to 17
This Toolkit provides web links, social media, posters and other COVID-19 related resources for people 15 to 17.
After You Travel
Depending on your travel history, you will be asked to stay home for a period of 14 days from the time you left an area with widespread or ongoing community spread.
Toolkit for Retirement Communities
COVID-19 guidance and tools to help retirement communities make decisions, protect their residents and staff, and communicate with their communities.
Focus on human factor in designing systems
A new study has found one of the challenges in designing systems that involve people interacting with technology is to tackle the human trait of overconfidence.
Toolkit for Older Adults and People at Higher Risk
Guidance and tools to help older adults and other people at higher risk protect themselves and their families. These resources can also help people who work with populations at higher risk make decisions, protect themselves and others, and communicate with their communities.
Battling COVID-19 using UV light
Researchers have found a possible breakthrough in how to manage COVID-19, as well as future viruses. It involves using polymer and oligomer materials activated with UV light in order to kill microbes on surfaces.
How blood and wealth can predict future disability
Research shows that blood tests for biomarkers such as cholesterol and inflammation can predict disability in five years. Researchers studied blood biomarkers of 5,286 participants involved in the UK Household Longitudinal Study - and found that biological health can predict disability and healthcare demand in five years' time. They also found that people on higher-incomes were more likely to seek GP appointments and outpatient treatments for their medical problems.
Several U.S. populations and regions exposed to high arsenic concentrations in drinking water
A national study of public water systems found that arsenic levels were not uniform across the U.S., even after implementation of the latest national regulatory standard. In the first study of differences in public drinking water arsenic exposures by geographic subgroups, researchers confirmed that community water systems reliant on groundwater, serving smaller populations located in the Southwest, and Hispanic communities were more likely to continue exceeding the national maximum containment level, raising environmental justice concerns.
Evolution may be to blame for high risk of advanced cancers in humans
Researchers discovered that most people no longer produce the Siglec-12 protein, but some of those who do are at twice the risk for advanced cancer.
Breast cancer survivors are less likely to get pregnant, but often have healthy babies and good long-term health
A large meta-analysis of breast cancer survivors of childbearing age indicated that they are less likely than the general public to get pregnant, and they face higher risk of certain complications such as preterm labor. However, most survivors who do get pregnant deliver healthy babies and have no adverse effects on their long-term survival, according to new data.
Significant increase in depression seen among children during first UK lockdown
The first lockdown led to a significant increase in symptoms of depression among children, highlighting the unintended consequences of school closures, according to a new study.
Stress and Coping
The COVID-19 outbreak may be stressful for people and may cause strong emotions in adults and children. Find ways you and your family can reduce stress.
Tomatoes offer affordable source of Parkinson's disease drug
Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.
Key driver of the spread of cancer to the brain
Approximately 200,000 cancer patients are diagnosed with brain metastases each year, yet few treatment options exist because the mechanisms that allow cancer to spread to the brain remain unclear. However, a study offers hope for the development of future therapies by showing how a poorly understood gene known as YTHDF3 plays a significant role in the process.
Using targeted microbubbles to administer toxic cancer drugs
New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumor using antibodies. Microbubbles are small manufactured spheres half the size of a red blood cell - and scientists believe they can be used to transport drugs to highly specific locations within the body.
Monitoring and Evaluating Mitigation Strategies in Child Care, K-12 Schools, and Institutions of Higher Education
As institutions of higher education (IHE), K-12 schools, and child care programs reopen or stay open for in-person instruction, it is important to monitor and evaluate COVID-19 mitigation strategies. These resources provide logic models that show the connection between activities and outcomes, example evaluation questions, indicators, data sources and other tools that evaluators and administrators of educational and public health institutions can use to monitor and evaluate the implementation and impact of COVID-19 mitigation strategies in these settings.
Using targeted microbubbles to administer toxic cancer drugs
New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumor using antibodies. Microbubbles are small manufactured spheres half the size of a red blood cell - and scientists believe they can be used to transport drugs to highly specific locations within the body.
FAQs for Correctional and Detention Facilities
FAQs for administrators, staff, people who are incarcerated, families
Prevent Getting Sick
Here is what you can do to prepare your family in case COVID-19 spreads in your community.
вторник, 8 декабря 2020 г.
Environmental impacts of the COVID-19 pandemic, as observed from space
COVID-19 has changed the way we live and work, as various health and safety restrictions keep more of us at home more often. The resulting changes to our behavior are already impacting the environment around us in myriad ways, according to comparisons of remote sensing data before and during the pandemic collected by NASA, U.S. Geological Survey (USGS), and ESA (European Space Agency) Earth-observing satellites and others.
Racial microaggressions contribute to disparities in STEM education
Careers in science, technology, engineering, and mathematics (STEM) are one of the fastest-growing areas of work in the United States, yet racial and gender disparities remain in STEM occupations. A recent study examining reasons for such disparities shows the overall racial climate on a college campus -- informed by experiences of racial microaggressions -- is a contributing factor in the lack of representation of students of color in STEM education programs.
Scientists shed new light on how lung bacteria defend against pneumonia
New insight on how bacteria in the lungs protect against invading pathogens has been published.
How poor oral hygiene may result in metabolic syndrome
Researchers have identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body.
Visual short-term memory is more complex than previously assumed
Contrary to previous assumptions, visual short-term memory is not merely based on one kind of information about an object, such as only its colour or only its name. Rather, several types of information can be retained simultaneously in short-term memory. Using complex EEG analyses and deep neural networks, researchers have discovered that short-term memory is more complex than previously assumed.
New findings shed light on the repair of UV-induced DNA damage
A repair system in our cells fixes DNA damage caused by exposure to ultraviolet (UV) light from the sun, however the detailed process behind this is not fully understood. An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system in recognizing and repairing UV-damaged DNA. This new discovery will contribute towards illuminating the onset mechanisms of diseases such as skin cancer.
'SCOUT' helps researchers find, quantify significant differences among organoids
Unbiased, high-throughput 'pipeline' system clears, labels, images and analyzes organoids to improve their utility for understanding development and diseases such as Zika infection.
Cases, Data, and Surveillance
CDC is aggressively responding to the global outbreak of COVID-19 and preparing for the potential of community spread in the United States.
Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Disease (COVID-19)
Clinicians, discover how you can best care for your hospitalized patients with a confirmed infection caused by novel coronavirus 2019 (COVID-19).
Risk of serious complications during knee replacement 73% higher when a tourniquet is used
The risk of developing serious complications following a knee replacement could be up to 73% higher when a tourniquet is used, compared to surgery without a tourniquet. Serious complications during knee replacement surgery are rare. However, researchers found that 5.9% of patients whose operations involved a tourniquet had serious complications needing additional health care, compared to 2.9% in those operated on without a tourniquet.
Magnetic bacteria as micropumps
Scientists use magnetic bacteria to control liquids at the micro level. They are already thinking about using them in the human bloodstream for precision delivery of cancer drugs to a tumor.
Toolkit for K-12 Schools
Toolkit to help keep K-12 school students and teachers safe during COVID-19 outbreak.
FAQs for Wildland Firefighters
Find answers to frequently asked questions from wildland firefighters regarding COVID-19.
Eyebuy: Sweeping glances can 'cost you money'
When Christmas shopping, customers should keep their eyes under control. As a study shows, visual attention can be strongly influenced during shopping with very simple interventions. The researchers report that unplanned purchases can even double as a result.
Current treatment period may be too short to remove competitive advantage of transgender athletes
Transgender women elite athletes may need more than the recommended year of feminising hormone therapy to remove the competitive advantage conferred by testosterone, suggests new research.
Teen dislike of physical appearance strong predictor of depression in early adulthood
Teens who are unhappy with their physical appearance are at significantly heightened risk of depression by the time they reach early adulthood.
Scientists discover how COVID-19 virus causes multiple organ failure in mice
Researchers have created a version of COVID-19 in mice that shows how the disease damages organs other than the lungs. Using their model, the scientists discovered that the SARS-CoV-2 virus can shut down energy production in cells of the heart, kidneys, spleen and other organs.
понедельник, 7 декабря 2020 г.
Why some people may become seriously ill from meningococcal bacteria
Researchers have come one step closer toward understanding why some people become seriously ill or die from a common bacterium that leaves most people unharmed. The researchers linked RNA mutations within the bacterium Neisseria meningitidis to invasive meningococcal disease, marking the first time a non-coding RNA in a bacterium has been linked to disease progression.
Deep rooted: Mother's empathy linked to 'epigenetic' changes to the oxytocin gene
Parenting behavior is deeply linked to the ability to empathize with one's children. Thus, to better understand why certain parents react to certain situations in a certain way, it is crucial to gain insight into how empathy is shaped. Scientists have now shed light on the interconnectedness among the oxytocin gene, brain structure, and maternal empathy.
Novel anti-craving mechanism discovered to treat cocaine relapse
Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder. Specifically, GLP-1R agonists, which are FDA-approved for treating diabetes and obesity, have been shown to reduce voluntary drug taking and seeking in preclinical models of cocaine used disorder.
Pupils can learn more effectively through stories than activities
Storytelling -- the oldest form of teaching -- is the most effective way of teaching primary school children about evolution, say researchers.
How do we separate the factual from the possible? New research shows how our brain responds to both
Our brains respond to language expressing facts differently than they do to words conveying possibility, a team of neuroscientists has found. Its work offers new insights into the impact word choice has on how we make distinctions between what's real vs. what's merely possible.
We're watching the world go blind, researchers say
Researchers say eye care accessibility around the globe isn't keeping up with an aging population, posing challenges for eye care professionals over the next 30 years.
Paper-based electrochemical sensor can detect COVID-19 in less than five minutes
Researchers have developed a rapid, ultrasensitive test using a paper-based electrochemical sensor that can detect the presence of the virus in less than five minutes. It uses a graphene biosensor and is adaptable to other viruses.
Machine learning identifies new brain network signature of major depression
Using machine learning, researchers have identified novel, distinct patterns of coordinated activity between different parts of the brain in people with major depressive disorder -- even when different protocols are used to detect these brain networks.
Synthetic llama antibodies rescue doomed proteins inside cells
Researchers created a new technology using synthetic llama antibodies to protect endangered proteins inside cells. The technology could treat dozens of diseases.
Notification of Exposure: A Contact Tracer's Guide for COVID-19
A Contact Tracer's Guide for COVID-19 focuses on communication strategies for contact interviews and provides suggested language for each topic area covered in an interview.
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